PDBsum entry: 3bub

Hydrolase

PDB-id: 3bub

Contents

Description

Header details

Header records

PROCHECK

Protein chain

1016 a.a. *

Ligands

NAG

MPD ×3

Metal ions

_ZN

Waters ×1493

* Residue conservation analysis

Tools

Clefts Calculation

PDB id:

3bub

Name:

Hydrolase

Title:

Golgi alpha-mannosidase ii with an empty active site

Structure:

Alpha-mannosidase 2. Chain: a. Fragment: catalytic domain. Unp residues 76-1108. Synonym: alpha-mannosidase ii, mannosyl-oligosaccharide 1, 3-1,6-alpha-mannosidase, man ii, golgi alpha-mannosidase ii, aman ii. Engineered: yes

Source:

Drosophila melanogaster. Fruit fly. Gene: alpha-man-ii, gmii. Expressed in: drosophila melanogaster.

UniProt:

Q24451 (MAN2_DROME)

Seq:

Struc:

Seq:

Struc:

Seq:

Struc:

Seq:

Struc:

Seq:

1108 a.a.

Struc:

1016 a.a.*

Key:	PfamA domain	PfamB domain
Secondary structure	CATH domain

* PDB and UniProt seqs differ at 1 residue position (black cross)

Enzyme class:

E.C.3.2.1.114   [IntEnz]   [ExPASy]   [KEGG]   [BRENDA]

Reaction:

Hydrolysis of the terminal 1,3- and 1,6-linked alpha-D-mannose residues in the mannosyl-oligosaccharide Man(5)(GlcNAc)(3).

Pathway:

Mannosyl-glycoprotein N-acetylglucosaminyltransferases

Resolution:

1.38Å

R-factor:

0.180

R-free:

0.204

Authors:

D.A.Kuntz,D.R.Rose

Date:

02-Jan-08

Release date:

01-Jul-08

Related entries:

1hty
dgmii + tris
1hww
dgmii + swainsonine
1hxk
dgmii + deoxymannojirimicin
1ps2
dgmii + kifunensine
1qwn
dgmii + 5fluoro-gulosylfluoride
... plus others (see Header records)

Quick_links

Procheck

Clefts

Surface