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PDBsum entry 3vf0

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protein ligands Protein-protein interface(s) links
Cell adhesion/protein binding PDB id
3vf0
Jmol
Contents
Protein chains
178 a.a.
283 a.a.
Ligands
EPE
GOL ×13
Waters ×254
PDB id:
3vf0
Name: Cell adhesion/protein binding
Title: Raver1 in complex with metavinculin l954 deletion mutant
Structure: Vinculin. Chain: a. Synonym: metavinculin. Engineered: yes. Ribonucleoprotein ptb-binding 1. Chain: b. Synonym: protein raver-1. Engineered: yes
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: vcl. Expressed in: escherichia coli. Expression_system_taxid: 511693. Gene: kiaa1978, raver1.
Resolution:
2.54Å     R-factor:   0.170     R-free:   0.205
Authors: J.H.Lee,C.Vonrhein,G.Bricogne,T.Izard
Key ref: J.H.Lee et al. (2012). The metavinculin tail domain directs constitutive interactions with raver1 and vinculin RNA. J Mol Biol, 422, 697-704. PubMed id: 22709580 DOI: 10.1016/j.jmb.2012.06.015
Date:
09-Jan-12     Release date:   25-Jul-12    
PROCHECK
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 Headers
 References

Protein chain
Pfam   ArchSchema ?
P18206  (VINC_HUMAN) -  Vinculin
Seq:
Struc:
 
Seq:
Struc:
 
Seq:
Struc:
1134 a.a.
178 a.a.
Protein chain
Pfam   ArchSchema ?
Q8IY67  (RAVR1_HUMAN) -  Ribonucleoprotein PTB-binding 1
Seq:
Struc:
 
Seq:
Struc:
606 a.a.
283 a.a.*
Key:    PfamA domain  Secondary structure  CATH domain
* PDB and UniProt seqs differ at 2 residue positions (black crosses)

 Gene Ontology (GO) functional annotation 
  GO annot!
  Cellular component     actin cytoskeleton   1 term 
  Biological process     cell adhesion   1 term 
  Biochemical function     structural molecule activity     3 terms  

 

 
DOI no: 10.1016/j.jmb.2012.06.015 J Mol Biol 422:697-704 (2012)
PubMed id: 22709580  
 
 
The metavinculin tail domain directs constitutive interactions with raver1 and vinculin RNA.
J.H.Lee, E.S.Rangarajan, C.Vonrhein, G.Bricogne, T.Izard.
 
  ABSTRACT  
 
No abstract given.