PDBsum entry 3vf0

Cell adhesion/protein binding

PDB id: 3vf0

Contents

Protein chains

178 a.a.

283 a.a.

Ligands

EPE

GOL ×13

Waters ×254

PDB id:

3vf0

Name:

Cell adhesion/protein binding

Title:

Raver1 in complex with metavinculin l954 deletion mutant

Structure:

Vinculin. Chain: a. Synonym: metavinculin. Engineered: yes. Ribonucleoprotein ptb-binding 1. Chain: b. Synonym: protein raver-1. Engineered: yes

Source:

Homo sapiens. Human. Organism_taxid: 9606. Gene: vcl. Expressed in: escherichia coli. Expression_system_taxid: 511693. Gene: kiaa1978, raver1.

Resolution:

2.54Å R-factor: 0.170 R-free: 0.205

Authors:

J.H.Lee,C.Vonrhein,G.Bricogne,T.Izard

Key ref:

J.H.Lee et al. (2012). The metavinculin tail domain directs constitutive interactions with raver1 and vinculin RNA. J Mol Biol, 422, 697-704. PubMed id: 22709580

Date:

09-Jan-12 Release date: 25-Jul-12

Protein chain

P18206  (VINC_HUMAN) -  Vinculin from Homo sapiens

Seq: 1134 a.a.

Struc: 178 a.a.

Protein chain

Q8IY67  (RAVR1_HUMAN) -  Ribonucleoprotein PTB-binding 1 from Homo sapiens

Seq: 606 a.a.

Struc: 283 a.a.*

* PDB and UniProt seqs differ at 2 residue positions (black crosses)

J Mol Biol 422:697-704 (2012)

PubMed id: 22709580

The metavinculin tail domain directs constitutive interactions with raver1 and vinculin RNA.

J.H.Lee, E.S.Rangarajan, C.Vonrhein, G.Bricogne, T.Izard.

ABSTRACT

No abstract given.