PDBsum entry 2kv2

Gene regulation

PDB id: 2kv2

Contents

Protein chain

85 a.a. *

* Residue conservation analysis

PDB id:

2kv2

Name:

Gene regulation

Title:

Solution structure of the human blm hrdc domain

Structure:

Bloom syndrome protein. Chain: a. Fragment: hrdc domain, unp residues 1210-1294. Synonym: blm, recq protein-like 3, DNA helicase, recq-like type 2, recq2. Engineered: yes

Source:

Homo sapiens. Human. Organism_taxid: 9606. Gene: blm. Expressed in: escherichia coli. Expression_system_taxid: 562.

NMR struc:

20 models

Authors:

Y.M.Kim,B.-S.Choi

Key ref:

Y.M.Kim and B.S.Choi (2010). Structure and function of the regulatory HRDC domain from human Bloom syndrome protein. Nucleic Acids Res, 38, 7764-7777. PubMed id: 20639533

Date:

04-Mar-10 Release date: 15-Dec-10

Protein chain

P54132  (BLM_HUMAN) -  RecQ-like DNA helicase BLM from Homo sapiens

Seq: 1417 a.a.

Struc: 85 a.a.

Enzyme reactions

• Enzyme class: E.C.3.6.4.12 - Dna helicase.
• Reaction: ATP + H2O = ADP + phosphate + H⁺

Molecule diagrams generated from .mol files obtained from the KEGG ftp site

reference

Nucleic Acids Res 38:7764-7777 (2010)

PubMed id: 20639533

Structure and function of the regulatory HRDC domain from human Bloom syndrome protein.

Y.M.Kim, B.S.Choi.

ABSTRACT

No abstract given.