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PDBsum entry 1vb6

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protein ligands Protein-protein interface(s) links
Signaling protein PDB id
1vb6
Jmol
Contents
Protein chains
114 a.a. *
Ligands
HEM
HEM-OXY
Waters ×315
* Residue conservation analysis
PDB id:
1vb6
Name: Signaling protein
Title: Crystal structure of the heme pas sensor domain of ec dos (o bound form)
Structure: Heme pas sensor protein. Chain: a, b. Fragment: heme pas domain. Engineered: yes
Source: Escherichia coli. Organism_taxid: 83333. Strain: k12. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Biol. unit: Dimer (from PQS)
Resolution:
1.56Å     R-factor:   0.214     R-free:   0.232
Authors: H.Kurokawa,M.Watanabe,I.Sagami,B.Mikami,T.Shimizu
Key ref: H.Kurokawa et al. Structure of oxygen-Bound form of a heme pas domain of EC dos. To be published, .
Date:
24-Feb-04     Release date:   19-Apr-05    
PROCHECK
Go to PROCHECK summary
 Headers
 References

Protein chains
Pfam   ArchSchema ?
P76129  (DOSP_ECOLI) -  Oxygen sensor protein DosP
Seq:
Struc:
 
Seq:
Struc:
799 a.a.
114 a.a.
Key:    PfamA domain  Secondary structure  CATH domain

 Enzyme reactions 
   Enzyme class: E.C.3.1.4.52  - Cyclic-guanylate-specific phosphodiesterase.
[IntEnz]   [ExPASy]   [KEGG]   [BRENDA]
      Reaction: Cyclic di-3',5'-guanylate + H2O = 5'-phosphoguanylyl(3'->5')guanosine
Cyclic di-3',5'-guanylate
+ H(2)O
= 5'-phosphoguanylyl(3'->5')guanosine
      Cofactor: Heme; Mg(2+); Mn(2+)
Heme
Bound ligand (Het Group name = HEM) matches with 95.45% similarity
Mg(2+)
Mn(2+)
Molecule diagrams generated from .mol files obtained from the KEGG ftp site
 Gene Ontology (GO) functional annotation 
  GO annot!
  Biological process     signal transduction   1 term 
  Biochemical function     signal transducer activity     1 term  

 

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