Dbfetch
LOCUS NM_136272 5055 bp mRNA linear INV 26-DEC-2023 DEFINITION Drosophila melanogaster adenylate cyclase 3, transcript variant A (Ac3), mRNA. ACCESSION NM_136272 VERSION NM_136272.3 DBLINK BioProject: PRJNA164 BioSample: SAMN02803731 KEYWORDS RefSeq. SOURCE Drosophila melanogaster (fruit fly) ORGANISM Drosophila melanogaster Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora. REFERENCE 1 (bases 1 to 5055) AUTHORS Matthews,B.B., Dos Santos,G., Crosby,M.A., Emmert,D.B., St Pierre,S.E., Gramates,L.S., Zhou,P., Schroeder,A.J., Falls,K., Strelets,V., Russo,S.M. and Gelbart,W.M. CONSRTM FlyBase Consortium TITLE Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data JOURNAL G3 (Bethesda) 5 (8), 1721-1736 (2015) PUBMED 26109357 REMARK Publication Status: Online-Only REFERENCE 2 (bases 1 to 5055) AUTHORS Crosby,M.A., Gramates,L.S., Dos Santos,G., Matthews,B.B., St Pierre,S.E., Zhou,P., Schroeder,A.J., Falls,K., Emmert,D.B., Russo,S.M. and Gelbart,W.M. CONSRTM FlyBase Consortium TITLE Gene Model Annotations for Drosophila melanogaster: The Rule-Benders JOURNAL G3 (Bethesda) 5 (8), 1737-1749 (2015) PUBMED 26109356 REMARK Publication Status: Online-Only REFERENCE 3 (bases 1 to 5055) AUTHORS Hoskins,R.A., Carlson,J.W., Wan,K.H., Park,S., Mendez,I., Galle,S.E., Booth,B.W., Pfeiffer,B.D., George,R.A., Svirskas,R., Krzywinski,M., Schein,J., Accardo,M.C., Damia,E., Messina,G., Mendez-Lago,M., de Pablos,B., Demakova,O.V., Andreyeva,E.N., Boldyreva,L.V., Marra,M., Carvalho,A.B., Dimitri,P., Villasante,A., Zhimulev,I.F., Rubin,G.M., Karpen,G.H. and Celniker,S.E. TITLE The Release 6 reference sequence of the Drosophila melanogaster genome JOURNAL Genome Res 25 (3), 445-458 (2015) PUBMED 25589440 REFERENCE 4 (bases 1 to 5055) AUTHORS Hoskins,R.A., Carlson,J.W., Kennedy,C., Acevedo,D., Evans-Holm,M., Frise,E., Wan,K.H., Park,S., Mendez-Lago,M., Rossi,F., Villasante,A., Dimitri,P., Karpen,G.H. and Celniker,S.E. TITLE Sequence finishing and mapping of Drosophila melanogaster heterochromatin JOURNAL Science 316 (5831), 1625-1628 (2007) PUBMED 17569867 REFERENCE 5 (bases 1 to 5055) AUTHORS Smith,C.D., Shu,S., Mungall,C.J. and Karpen,G.H. TITLE The Release 5.1 annotation of Drosophila melanogaster heterochromatin JOURNAL Science 316 (5831), 1586-1591 (2007) PUBMED 17569856 REMARK Erratum:[Science. 2007 Sep 7;317(5843):1325] REFERENCE 6 (bases 1 to 5055) AUTHORS Quesneville,H., Bergman,C.M., Andrieu,O., Autard,D., Nouaud,D., Ashburner,M. and Anxolabehere,D. TITLE Combined evidence annotation of transposable elements in genome sequences JOURNAL PLoS Comput Biol 1 (2), 166-175 (2005) PUBMED 16110336 REFERENCE 7 (bases 1 to 5055) AUTHORS Hoskins,R.A., Smith,C.D., Carlson,J.W., Carvalho,A.B., Halpern,A., Kaminker,J.S., Kennedy,C., Mungall,C.J., Sullivan,B.A., Sutton,G.G., Yasuhara,J.C., Wakimoto,B.T., Myers,E.W., Celniker,S.E., Rubin,G.M. and Karpen,G.H. TITLE Heterochromatic sequences in a Drosophila whole-genome shotgun assembly JOURNAL Genome Biol 3 (12), RESEARCH0085 (2002) PUBMED 12537574 REFERENCE 8 (bases 1 to 5055) AUTHORS Kaminker,J.S., Bergman,C.M., Kronmiller,B., Carlson,J., Svirskas,R., Patel,S., Frise,E., Wheeler,D.A., Lewis,S.E., Rubin,G.M., Ashburner,M. and Celniker,S.E. TITLE The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective JOURNAL Genome Biol 3 (12), RESEARCH0084 (2002) PUBMED 12537573 REFERENCE 9 (bases 1 to 5055) AUTHORS Misra,S., Crosby,M.A., Mungall,C.J., Matthews,B.B., Campbell,K.S., Hradecky,P., Huang,Y., Kaminker,J.S., Millburn,G.H., Prochnik,S.E., Smith,C.D., Tupy,J.L., Whitfied,E.J., Bayraktaroglu,L., Berman,B.P., Bettencourt,B.R., Celniker,S.E., de Grey,A.D., Drysdale,R.A., Harris,N.L., Richter,J., Russo,S., Schroeder,A.J., Shu,S.Q., Stapleton,M., Yamada,C., Ashburner,M., Gelbart,W.M., Rubin,G.M. and Lewis,S.E. TITLE Annotation of the Drosophila melanogaster euchromatic genome: a systematic review JOURNAL Genome Biol 3 (12), RESEARCH0083 (2002) PUBMED 12537572 REFERENCE 10 (bases 1 to 5055) AUTHORS Celniker,S.E., Wheeler,D.A., Kronmiller,B., Carlson,J.W., Halpern,A., Patel,S., Adams,M., Champe,M., Dugan,S.P., Frise,E., Hodgson,A., George,R.A., Hoskins,R.A., Laverty,T., Muzny,D.M., Nelson,C.R., Pacleb,J.M., Park,S., Pfeiffer,B.D., Richards,S., Sodergren,E.J., Svirskas,R., Tabor,P.E., Wan,K., Stapleton,M., Sutton,G.G., Venter,C., Weinstock,G., Scherer,S.E., Myers,E.W., Gibbs,R.A. and Rubin,G.M. TITLE Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence JOURNAL Genome Biol 3 (12), RESEARCH0079 (2002) PUBMED 12537568 REFERENCE 11 (bases 1 to 5055) AUTHORS Adams,M.D., Celniker,S.E., Holt,R.A., Evans,C.A., Gocayne,J.D., Amanatides,P.G., Scherer,S.E., Li,P.W., Hoskins,R.A., Galle,R.F., George,R.A., Lewis,S.E., Richards,S., Ashburner,M., Henderson,S.N., Sutton,G.G., Wortman,J.R., Yandell,M.D., Zhang,Q., Chen,L.X., Brandon,R.C., Rogers,Y.H., Blazej,R.G., Champe,M., Pfeiffer,B.D., Wan,K.H., Doyle,C., Baxter,E.G., Helt,G., Nelson,C.R., Gabor,G.L., Abril,J.F., Agbayani,A., An,H.J., Andrews-Pfannkoch,C., Baldwin,D., Ballew,R.M., Basu,A., Baxendale,J., Bayraktaroglu,L., Beasley,E.M., Beeson,K.Y., Benos,P.V., Berman,B.P., Bhandari,D., Bolshakov,S., Borkova,D., Botchan,M.R., Bouck,J., Brokstein,P., Brottier,P., Burtis,K.C., Busam,D.A., Butler,H., Cadieu,E., Center,A., Chandra,I., Cherry,J.M., Cawley,S., Dahlke,C., Davenport,L.B., Davies,P., de Pablos,B., Delcher,A., Deng,Z., Mays,A.D., Dew,I., Dietz,S.M., Dodson,K., Doup,L.E., Downes,M., Dugan-Rocha,S., Dunkov,B.C., Dunn,P., Durbin,K.J., Evangelista,C.C., Ferraz,C., Ferriera,S., Fleischmann,W., Fosler,C., Gabrielian,A.E., Garg,N.S., Gelbart,W.M., Glasser,K., Glodek,A., Gong,F., Gorrell,J.H., Gu,Z., Guan,P., Harris,M., Harris,N.L., Harvey,D., Heiman,T.J., Hernandez,J.R., Houck,J., Hostin,D., Houston,K.A., Howland,T.J., Wei,M.H., Ibegwam,C., Jalali,M., Kalush,F., Karpen,G.H., Ke,Z., Kennison,J.A., Ketchum,K.A., Kimmel,B.E., Kodira,C.D., Kraft,C., Kravitz,S., Kulp,D., Lai,Z., Lasko,P., Lei,Y., Levitsky,A.A., Li,J., Li,Z., Liang,Y., Lin,X., Liu,X., Mattei,B., McIntosh,T.C., McLeod,M.P., McPherson,D., Merkulov,G., Milshina,N.V., Mobarry,C., Morris,J., Moshrefi,A., Mount,S.M., Moy,M., Murphy,B., Murphy,L., Muzny,D.M., Nelson,D.L., Nelson,D.R., Nelson,K.A., Nixon,K., Nusskern,D.R., Pacleb,J.M., Palazzolo,M., Pittman,G.S., Pan,S., Pollard,J., Puri,V., Reese,M.G., Reinert,K., Remington,K., Saunders,R.D., Scheeler,F., Shen,H., Shue,B.C., Siden-Kiamos,I., Simpson,M., Skupski,M.P., Smith,T., Spier,E., Spradling,A.C., Stapleton,M., Strong,R., Sun,E., Svirskas,R., Tector,C., Turner,R., Venter,E., Wang,A.H., Wang,X., Wang,Z.Y., Wassarman,D.A., Weinstock,G.M., Weissenbach,J., Williams,S.M., WoodageT, Worley,K.C., Wu,D., Yang,S., Yao,Q.A., Ye,J., Yeh,R.F., Zaveri,J.S., Zhan,M., Zhang,G., Zhao,Q., Zheng,L., Zheng,X.H., Zhong,F.N., Zhong,W., Zhou,X., Zhu,S., Zhu,X., Smith,H.O., Gibbs,R.A., Myers,E.W., Rubin,G.M. and Venter,J.C. TITLE The genome sequence of Drosophila melanogaster JOURNAL Science 287 (5461), 2185-2195 (2000) PUBMED 10731132 REFERENCE 12 (bases 1 to 5055) AUTHORS Celniker,S., Carlson,J., Wan,K., Pfeiffer,B., Frise,E., George,R., Hoskins,R., Stapleton,M., Pacleb,J., Park,S., Svirskas,R., Smith,E., Yu,C. and Rubin,G. CONSRTM Berkeley Drosophila Genome Project TITLE Drosophila melanogaster release 4 sequence JOURNAL Unpublished REFERENCE 13 (bases 1 to 5055) CONSRTM NCBI Genome Project TITLE Direct Submission JOURNAL Submitted (20-DEC-2023) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA REFERENCE 14 (bases 1 to 5055) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (13-DEC-2023) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 15 (bases 1 to 5055) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (10-NOV-2022) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 16 (bases 1 to 5055) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (19-OCT-2022) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 17 (bases 1 to 5055) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (20-APR-2020) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 18 (bases 1 to 5055) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (22-APR-2019) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 19 (bases 1 to 5055) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (24-MAY-2018) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 20 (bases 1 to 5055) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (07-DEC-2016) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 21 (bases 1 to 5055) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (07-OCT-2015) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 22 (bases 1 to 5055) AUTHORS Celniker,S., Carlson,J., Kennedy,C., Wan,K., Frise,E., Hoskins,R., Park,S., Svirskas,R. and Karpen,G. TITLE Direct Submission JOURNAL Submitted (10-AUG-2006) Berkeley Drosophila Genome Project, Lawrence Berkeley National Laboratory, One #Cyclotron RoadOne Cyclotron Road, MS 64-121, Berkeley, CA 94720, USA REMARK Direct Submission REFERENCE 23 (bases 1 to 5055) AUTHORS Celniker,S., Carlson,J., Wan,K., Frise,E., Hoskins,R., Park,S., Svirskas,R. and Rubin,G. TITLE Direct Submission JOURNAL Submitted (10-AUG-2006) Berkeley Drosophila Genome Project, Lawrence Berkeley National Laboratory, One Cyclotron Road, MS 64-121, Berkeley, CA 94720, USA REMARK Direct Submission REFERENCE 24 (bases 1 to 5055) AUTHORS Smith,C.D., Shu,S., Mungall,C.J. and Karpen,G.H. CONSRTM Drosophila Heterochromatin Genome Project TITLE Direct Submission JOURNAL Submitted (01-AUG-2006) Drosophila Heterochromatin Genome Project, Ernest Orlando Lawrence Berkeley National Laboratory, 1 Cyclotron Road, Mailstop 64-121, Berkeley, CA 94720, USA REFERENCE 25 (bases 1 to 5055) AUTHORS Adams,M.D., Celniker,S.E., Gibbs,R.A., Rubin,G.M. and Venter,C.J. TITLE Direct Submission JOURNAL Submitted (21-MAR-2000) Celera Genomics, 45 West Gude Drive, Rockville, MD 20850, USA COMMENT REVIEWED REFSEQ: This record has been curated by FlyBase. This record is derived from an annotated genomic sequence (NT_033779). On Jan 16, 2013 this sequence version replaced NM_136272.2. ##Genome-Annotation-Data-START## Annotation Provider :: FlyBase Annotation Status :: Full annotation Annotation Version :: Release 6.54 URL :: http://flybase.org ##Genome-Annotation-Data-END## FEATURES Location/Qualifiers source 1..5055 /organism="Drosophila melanogaster" /mol_type="mRNA" /db_xref="taxon:7227" /chromosome="2L" /genotype="y[1]; Gr22b[1] Gr22d[1] cn[1] CG33964[R4.2] bw[1] sp[1]; LysC[1] MstProx[1] GstD5[1] Rh6[1]" gene 1..5055 /gene="Ac3" /locus_tag="Dmel_CG1506" /gene_synonym="AC 3; ac3; AC3; CG1506; DAC3; DAC39E; dADCY3; Dmel\CG1506" /note="Adenylate cyclase 3" /map="39E3-39E3" /db_xref="FLYBASE:FBgn0023416" /db_xref="GeneID:35419" CDS 413..3916 /gene="Ac3" /locus_tag="Dmel_CG1506" /gene_synonym="AC 3; ac3; AC3; CG1506; DAC3; DAC39E; dADCY3; Dmel\CG1506" /EC_number="4.6.-.-" /EC_number="4.6.1.1" /note="CG1506 gene product from transcript CG1506-RA; CG1506-PA; Ac3-PA; adenylate cyclase 3" /codon_start=1 /product="adenylate cyclase 3, isoform A" /protein_id="NP_610116.2" /db_xref="FLYBASE:FBpp0085252" /db_xref="GeneID:35419" /db_xref="FLYBASE:FBgn0023416" /translation="MEANLENGQKTIASTSKSHSQRQTTSRRRQNDSDVAGGVGITGG GVVILPQHVLNELYHNYSIKQRRSGLKWFVFAAALFNIWTIGIPWDQSAPTRVINCCM LLAYLALTALLHIGRRSDKPALRRFHQILLIIVPRALWLLSILHFTVYVILQPSFSPR DLLGWAILLNFLVYVTLPLQLIFLGLSIGCITYFICLSLPVGYSHWDSLLSNQLAANA VLIATAALIGLLYYFMGEAKQKRAFLEAKKSLEVKMVIEEQSAEQERLLLSVLPKHVA IKMREDLGSSSSEAFKKIYMSRHENVSILYADIVGFTAISSTYSAQDLVKMLNELFAR FDRLAEKYQQLRIKILGDCYYCISGAPDERPDHAVLCVHMGLSMVKAIKYVQQKANSP VDMRVGIHTGAVLAGILGQRQWQFDVYSKDVELANKMESSGKAGRVHISDKTLAFLNG EFEVEAAFGEKREELLRIAGLKTYFITKVVKAFASPCAKKINETQAEIAHPNPNGSTT DIVSDEDDNDATLDDEELLAQNSVSNGHQIGIAVTADEEEQVKLENFKQRLKDELVTR DGHENLTKDTNIFLRFKNPQLEQLYAVYREPYSSLPLLAALLVQCIDVLYSYLVLPRS TLHFINIAAPLVPIAMLVVISLAESFSGMLPKFFVDVSKRFNDITFVRELAAIIIALT IGFSNVIDMFFFVTFVRTEHIVSESEFNVTASLESDINLVVEGMVTAEHLLPASFVEQ MRDAVPTERVLYPSYLSNFGVLILIAIAVIAQLTHLTKILLLLSIAALHCYFNIFIMQ DLYALEDDFEHQPIISTRYAASGLLLVAALALSTLARHMDHEDRVIFKWKTEVAEQKE TANDMRQRNEALVYNVLPVHVAEHFMKNTKRSHDDLYSQSYAEVGVLFASMPNFSDFY SEETVNNQGLECLRFLNEVISDFDALLELPQFQDIIKIKTIGSTYMAASGINVQRTVR NDAPITERWSHLAILVEFALELKHALQSINEQSFNHFVLKMGINHGPITAGVIGARKP HYDIWGNTVNVASRMESTGKAGAIQVTEETCNILRLFGYTFLQRGLVAVKGKGQLMTF YLQGKSQSSAEPVASGVVVLNGQDSSAVESTSELEASDIKMPLLKMNGPEQSLEIDQD RSLRNDSAGQESVAECQSLLE" ORIGIN 1 agtcaagttt atcggggcgg cttagtttag tcgaaggata ttgctcggtg tcttgcgtgc 61 aaacttgcta gcagaaaaaa tttaacacat cgaaaaagca aataaccagc atagcaaact 121 tccattacgg caataaatgt gcggtacagc catatgcagg acgcttccgc agtgcattta 181 atttgagtgg acggaggatg caccgataag tgtcaagatt acttgcttat actttgtccc 241 tgtatttcga ttttgccttg cagtgcttcg attcagacaa gtgaactatt ttatgttctt 301 gtcacattac aaacaaataa accaaggaca tggtgtcgct ttattactaa accacaaata 361 cgaaataagc tctccgaaca acgaataaca tcctagaagt tagacaaacg agatggaagc 421 aaatttggag aacggtcaga aaacgatcgc ctcgacaagc aaatcgcatt cgcagcgtca 481 aacaacatct cgacggcggc aaaacgacag cgatgtggcc ggaggcgtgg gaatcaccgg 541 tgggggagtc gtcattttgc cgcagcacgt gcttaacgaa ctctaccaca actactccat 601 caaacaacgc cgcagtggat tgaagtggtt tgtctttgcg gccgcgttgt ttaacatatg 661 gaccatcgga attccctggg atcagtcggc ccctacgaga gtgatcaact gttgtatgct 721 gttagcttac ttggcattga cagcgctcct tcatattgga cgccgttctg ataaaccggc 781 actgaggcgc ttccaccaaa tactcctgat tattgtgcca cgggcactgt ggctattaag 841 cattcttcat tttaccgttt atgttattct gcagcctagt ttttctccaa gggacctact 901 tggctgggcc atccttctaa atttcttggt ctatgtgacg ctgccattac agctgatttt 961 tcttggtctg tcgattggat gtatcacata tttcatttgc ctcagtctcc ctgttggtta 1021 ttctcactgg gactcgctgc tctcgaacca attagcggct aatgcagttt tgatagccac 1081 ggcagcgctg ataggccttt tgtactactt tatgggtgag gccaagcaga aacgagcctt 1141 tctcgaggcc aaaaagagcc ttgaagttaa aatggtcata gaggaacagt cggccgaaca 1201 ggagcgtctg ctattgtctg tgctgccaaa gcatgtggct attaagatgc gggaagattt 1261 gggatcatcc agttccgagg cttttaaaaa aatttacatg agtcggcacg agaatgtaag 1321 cattctatat gcggatatcg ttggctttac cgccatctcc tccacatata gtgcgcaaga 1381 tttggtaaaa atgcttaacg agctctttgc acgtttcgac agacttgctg agaaatatca 1441 acaattgcgc attaagattc ttggcgattg ctactactgt attagcggtg cccctgatga 1501 gcgtccagat cacgccgtcc tgtgtgtgca catgggactc tccatggtga aggccattaa 1561 gtatgtgcag cagaaggcca actcacctgt tgacatgcga gtaggcattc acactggagc 1621 cgtgctcgct ggaattcttg ggcagcgaca gtggcagttt gatgtttact ctaaggacgt 1681 agagctggct aataaaatgg aatcgagcgg aaaggctgga cgcgttcaca tttcggacaa 1741 aacgcttgcc tttctgaacg gcgaattcga agtggaggcc gcctttggag agaaacgaga 1801 ggagttgttg cgtattgctg ggctaaagac gtattttatc accaaagtag ttaaagcgtt 1861 tgcatcgcca tgtgccaaaa aaataaatga aacccaggct gaaattgcac accccaatcc 1921 taatggatcg acgaccgata ttgtatcaga tgaagatgac aacgatgcca cattagacga 1981 cgaagagctc ctggcgcaga attctgtatc caatggacac caaataggga ttgcagtgac 2041 tgcagatgaa gaggagcagg tgaaattgga gaactttaaa caacgactga aagatgagct 2101 ggtaacgcgc gacggacatg aaaacctaac caaggacact aacatattct tgcgcttcaa 2161 aaacccccag ctggagcaac tgtatgccgt atatagagag ccgtacagtt cacttccact 2221 tcttgccgct cttctagtgc agtgcattga tgtgctgtac tcatacttag ttctcccgag 2281 atctacactc cacttcatta atatagctgc tccgttggtg ccgatcgcaa tgctggtagt 2341 gatcagcctt gccgagagct ttagcggcat gctgcccaag ttttttgtag atgtcagcaa 2401 gcgcttcaat gacataacct ttgttcgcga gctggcagcc ataattattg cactcaccat 2461 tggcttcagt aacgtaatcg acatgttctt tttcgtcacc ttcgtgcgta ccgagcatat 2521 tgtgagtgaa agcgagttca atgtaacggc tagcctagaa agcgatataa acttggtggt 2581 ggaggggatg gtcaccgcag agcacctact tcccgcatcg tttgtggaac aaatgcgaga 2641 tgctgtgcct acggaacgag ttctgtatcc gtcctactta agtaacttcg gagtactcat 2701 attaattgcg attgccgtga ttgcccaact tactcatctc acaaagattt tgctactatt 2761 gtccattgca gctctgcatt gctatttcaa tatattcatc atgcaggatc tttatgctct 2821 agaggatgat ttcgaacatc aacctattat atctacgcga tatgccgctt caggactttt 2881 gcttgtggct gctctggcgt taagcacctt ggcaagacac atggaccacg aggatagggt 2941 aatattcaag tggaaaaccg aggtggctga gcaaaaggag accgcaaacg acatgaggca 3001 gcgaaatgag gctttggtct acaatgtctt acctgttcat gtggcagagc acttcatgaa 3061 gaacactaaa cgctctcatg atgatcttta ttcccagagc tatgctgaag tgggcgtatt 3121 atttgccagc atgccgaact tttctgattt ctattccgaa gaaacagtaa acaaccaggg 3181 cttggaatgt ttacgttttc tcaatgaggt catctcagat tttgatgcat tgttggagct 3241 gccacaattc caagacatca tcaaaataaa aactattggt tcgacatata tggctgccag 3301 tgggataaat gtgcaaagga ctgtccgaaa tgacgcccca attacagaac ggtggtctca 3361 cttagcgatt ttggtggagt tcgcactgga actgaagcac gcattgcaaa gcatcaacga 3421 gcagtcgttt aaccacttcg tccttaagat ggggatcaat catggaccga tcacggctgg 3481 cgttattggc gcacgtaaac cgcattacga catctggggt aatacggtga atgtggcatc 3541 gcgaatggaa agcacaggaa aggcgggcgc cattcaggtc acggaagaga cgtgcaatat 3601 tttacggctc tttggttaca ccttccttca gcgtggcctg gtagcggtca agggaaaagg 3661 acagctgatg acattttatc tgcagggtaa gtcccagtcg agtgctgaac cggtagcatc 3721 cggcgtagtc gtgctcaatg ggcaggattc atctgctgta gaatccacaa gcgaactgga 3781 ggcctcagac attaaaatgc ccttgctgaa gatgaatggc ccagagcaat cgttggaaat 3841 cgaccaagat cgaagcttaa gaaatgacag tgctggccaa gagagtgtgg cagaatgtca 3901 gtctttgcta gaatagtaag cttgtcatat ttatgatttt cattctttgt gaacatttag 3961 gatgagtgga tgtgtatgcg tgtgagtggc cgtgttaaaa aaacaagagt taactatttt 4021 gaagaaatta tttttgcaat aagttaggtt ttgcctcagt gttcgtgtga tattccatgc 4081 aagatgatta ataaaataaa taagcaaaat tcgaaattag ttaacataat agatttgctt 4141 ttgtaaactg tgtacctaaa acaagaaata tatctatctt ctaagtatat ttttgtatgt 4201 ttagtatttt cagttattct aaaccatagt tcgtttaaaa aaatttgaca ttttcgaagc 4261 tctgtaatat ttaagtgatt cgctttgcag ctaattgatg tgcagattag catctcaatg 4321 tgtaaaatat atatatccgc attatagtta aaaccaaaat tacgatataa ataacattgc 4381 agttatagaa atatagaatt tatattagtt gagagtccaa atcccaccat atacaactaa 4441 aacccacgtg tcagtccaaa ttgagaacaa aagatactac aattaattag taaaaaagta 4501 ttaaatataa aaatggaaat gaaatcaaag aacaaaaata taatccttag aatgcgttct 4561 tggacgtcgt caaccaacat tataccttca tatatataga aatatttaaa ttaaaacaaa 4621 cttattagca ttgcatgctt tttaaaacat tgcaacgaat tttagcaaac aaacgaaatt 4681 aattatcaaa agttgcaaaa taaacaagga acttgaccta aaatcttttg aatgcgtttg 4741 tccatcagtt tttttttact gcattatgta agttttgctt tgatggttta aggcatgaca 4801 atcaagatga ataaacacta tacaaatgat tgggttagct cgaaattcca cagtttaaaa 4861 acactatgaa ctatttttaa aacatacatt ttattgaatg attttagaag attgggtcgt 4921 tgtgttggtt tcttcatgga accttaatgt gaaataaggt tttatttcat taaatataaa 4981 ttaactaaga tataaattat ttaaaaccta ccaaatatag caaattttag agaaataaat 5041 aaaattattt aagac //