Dbfetch
LOCUS NM_001259769 6349 bp mRNA linear INV 26-DEC-2023 DEFINITION Drosophila melanogaster transmembrane channel-like, transcript variant D (Tmc), mRNA. ACCESSION NM_001259769 VERSION NM_001259769.3 DBLINK BioProject: PRJNA164 BioSample: SAMN02803731 KEYWORDS RefSeq. SOURCE Drosophila melanogaster (fruit fly) ORGANISM Drosophila melanogaster Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora. REFERENCE 1 (bases 1 to 6349) AUTHORS Matthews,B.B., Dos Santos,G., Crosby,M.A., Emmert,D.B., St Pierre,S.E., Gramates,L.S., Zhou,P., Schroeder,A.J., Falls,K., Strelets,V., Russo,S.M. and Gelbart,W.M. CONSRTM FlyBase Consortium TITLE Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data JOURNAL G3 (Bethesda) 5 (8), 1721-1736 (2015) PUBMED 26109357 REMARK Publication Status: Online-Only REFERENCE 2 (bases 1 to 6349) AUTHORS Crosby,M.A., Gramates,L.S., Dos Santos,G., Matthews,B.B., St Pierre,S.E., Zhou,P., Schroeder,A.J., Falls,K., Emmert,D.B., Russo,S.M. and Gelbart,W.M. CONSRTM FlyBase Consortium TITLE Gene Model Annotations for Drosophila melanogaster: The Rule-Benders JOURNAL G3 (Bethesda) 5 (8), 1737-1749 (2015) PUBMED 26109356 REMARK Publication Status: Online-Only REFERENCE 3 (bases 1 to 6349) AUTHORS Hoskins,R.A., Carlson,J.W., Wan,K.H., Park,S., Mendez,I., Galle,S.E., Booth,B.W., Pfeiffer,B.D., George,R.A., Svirskas,R., Krzywinski,M., Schein,J., Accardo,M.C., Damia,E., Messina,G., Mendez-Lago,M., de Pablos,B., Demakova,O.V., Andreyeva,E.N., Boldyreva,L.V., Marra,M., Carvalho,A.B., Dimitri,P., Villasante,A., Zhimulev,I.F., Rubin,G.M., Karpen,G.H. and Celniker,S.E. TITLE The Release 6 reference sequence of the Drosophila melanogaster genome JOURNAL Genome Res 25 (3), 445-458 (2015) PUBMED 25589440 REFERENCE 4 (bases 1 to 6349) AUTHORS Hoskins,R.A., Carlson,J.W., Kennedy,C., Acevedo,D., Evans-Holm,M., Frise,E., Wan,K.H., Park,S., Mendez-Lago,M., Rossi,F., Villasante,A., Dimitri,P., Karpen,G.H. and Celniker,S.E. TITLE Sequence finishing and mapping of Drosophila melanogaster heterochromatin JOURNAL Science 316 (5831), 1625-1628 (2007) PUBMED 17569867 REFERENCE 5 (bases 1 to 6349) AUTHORS Smith,C.D., Shu,S., Mungall,C.J. and Karpen,G.H. TITLE The Release 5.1 annotation of Drosophila melanogaster heterochromatin JOURNAL Science 316 (5831), 1586-1591 (2007) PUBMED 17569856 REMARK Erratum:[Science. 2007 Sep 7;317(5843):1325] REFERENCE 6 (bases 1 to 6349) AUTHORS Quesneville,H., Bergman,C.M., Andrieu,O., Autard,D., Nouaud,D., Ashburner,M. and Anxolabehere,D. TITLE Combined evidence annotation of transposable elements in genome sequences JOURNAL PLoS Comput Biol 1 (2), 166-175 (2005) PUBMED 16110336 REFERENCE 7 (bases 1 to 6349) AUTHORS Hoskins,R.A., Smith,C.D., Carlson,J.W., Carvalho,A.B., Halpern,A., Kaminker,J.S., Kennedy,C., Mungall,C.J., Sullivan,B.A., Sutton,G.G., Yasuhara,J.C., Wakimoto,B.T., Myers,E.W., Celniker,S.E., Rubin,G.M. and Karpen,G.H. TITLE Heterochromatic sequences in a Drosophila whole-genome shotgun assembly JOURNAL Genome Biol 3 (12), RESEARCH0085 (2002) PUBMED 12537574 REFERENCE 8 (bases 1 to 6349) AUTHORS Kaminker,J.S., Bergman,C.M., Kronmiller,B., Carlson,J., Svirskas,R., Patel,S., Frise,E., Wheeler,D.A., Lewis,S.E., Rubin,G.M., Ashburner,M. and Celniker,S.E. TITLE The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective JOURNAL Genome Biol 3 (12), RESEARCH0084 (2002) PUBMED 12537573 REFERENCE 9 (bases 1 to 6349) AUTHORS Misra,S., Crosby,M.A., Mungall,C.J., Matthews,B.B., Campbell,K.S., Hradecky,P., Huang,Y., Kaminker,J.S., Millburn,G.H., Prochnik,S.E., Smith,C.D., Tupy,J.L., Whitfied,E.J., Bayraktaroglu,L., Berman,B.P., Bettencourt,B.R., Celniker,S.E., de Grey,A.D., Drysdale,R.A., Harris,N.L., Richter,J., Russo,S., Schroeder,A.J., Shu,S.Q., Stapleton,M., Yamada,C., Ashburner,M., Gelbart,W.M., Rubin,G.M. and Lewis,S.E. TITLE Annotation of the Drosophila melanogaster euchromatic genome: a systematic review JOURNAL Genome Biol 3 (12), RESEARCH0083 (2002) PUBMED 12537572 REFERENCE 10 (bases 1 to 6349) AUTHORS Celniker,S.E., Wheeler,D.A., Kronmiller,B., Carlson,J.W., Halpern,A., Patel,S., Adams,M., Champe,M., Dugan,S.P., Frise,E., Hodgson,A., George,R.A., Hoskins,R.A., Laverty,T., Muzny,D.M., Nelson,C.R., Pacleb,J.M., Park,S., Pfeiffer,B.D., Richards,S., Sodergren,E.J., Svirskas,R., Tabor,P.E., Wan,K., Stapleton,M., Sutton,G.G., Venter,C., Weinstock,G., Scherer,S.E., Myers,E.W., Gibbs,R.A. and Rubin,G.M. TITLE Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence JOURNAL Genome Biol 3 (12), RESEARCH0079 (2002) PUBMED 12537568 REFERENCE 11 (bases 1 to 6349) AUTHORS Adams,M.D., Celniker,S.E., Holt,R.A., Evans,C.A., Gocayne,J.D., Amanatides,P.G., Scherer,S.E., Li,P.W., Hoskins,R.A., Galle,R.F., George,R.A., Lewis,S.E., Richards,S., Ashburner,M., Henderson,S.N., Sutton,G.G., Wortman,J.R., Yandell,M.D., Zhang,Q., Chen,L.X., Brandon,R.C., Rogers,Y.H., Blazej,R.G., Champe,M., Pfeiffer,B.D., Wan,K.H., Doyle,C., Baxter,E.G., Helt,G., Nelson,C.R., Gabor,G.L., Abril,J.F., Agbayani,A., An,H.J., Andrews-Pfannkoch,C., Baldwin,D., Ballew,R.M., Basu,A., Baxendale,J., Bayraktaroglu,L., Beasley,E.M., Beeson,K.Y., Benos,P.V., Berman,B.P., Bhandari,D., Bolshakov,S., Borkova,D., Botchan,M.R., Bouck,J., Brokstein,P., Brottier,P., Burtis,K.C., Busam,D.A., Butler,H., Cadieu,E., Center,A., Chandra,I., Cherry,J.M., Cawley,S., Dahlke,C., Davenport,L.B., Davies,P., de Pablos,B., Delcher,A., Deng,Z., Mays,A.D., Dew,I., Dietz,S.M., Dodson,K., Doup,L.E., Downes,M., Dugan-Rocha,S., Dunkov,B.C., Dunn,P., Durbin,K.J., Evangelista,C.C., Ferraz,C., Ferriera,S., Fleischmann,W., Fosler,C., Gabrielian,A.E., Garg,N.S., Gelbart,W.M., Glasser,K., Glodek,A., Gong,F., Gorrell,J.H., Gu,Z., Guan,P., Harris,M., Harris,N.L., Harvey,D., Heiman,T.J., Hernandez,J.R., Houck,J., Hostin,D., Houston,K.A., Howland,T.J., Wei,M.H., Ibegwam,C., Jalali,M., Kalush,F., Karpen,G.H., Ke,Z., Kennison,J.A., Ketchum,K.A., Kimmel,B.E., Kodira,C.D., Kraft,C., Kravitz,S., Kulp,D., Lai,Z., Lasko,P., Lei,Y., Levitsky,A.A., Li,J., Li,Z., Liang,Y., Lin,X., Liu,X., Mattei,B., McIntosh,T.C., McLeod,M.P., McPherson,D., Merkulov,G., Milshina,N.V., Mobarry,C., Morris,J., Moshrefi,A., Mount,S.M., Moy,M., Murphy,B., Murphy,L., Muzny,D.M., Nelson,D.L., Nelson,D.R., Nelson,K.A., Nixon,K., Nusskern,D.R., Pacleb,J.M., Palazzolo,M., Pittman,G.S., Pan,S., Pollard,J., Puri,V., Reese,M.G., Reinert,K., Remington,K., Saunders,R.D., Scheeler,F., Shen,H., Shue,B.C., Siden-Kiamos,I., Simpson,M., Skupski,M.P., Smith,T., Spier,E., Spradling,A.C., Stapleton,M., Strong,R., Sun,E., Svirskas,R., Tector,C., Turner,R., Venter,E., Wang,A.H., Wang,X., Wang,Z.Y., Wassarman,D.A., Weinstock,G.M., Weissenbach,J., Williams,S.M., WoodageT, Worley,K.C., Wu,D., Yang,S., Yao,Q.A., Ye,J., Yeh,R.F., Zaveri,J.S., Zhan,M., Zhang,G., Zhao,Q., Zheng,L., Zheng,X.H., Zhong,F.N., Zhong,W., Zhou,X., Zhu,S., Zhu,X., Smith,H.O., Gibbs,R.A., Myers,E.W., Rubin,G.M. and Venter,J.C. TITLE The genome sequence of Drosophila melanogaster JOURNAL Science 287 (5461), 2185-2195 (2000) PUBMED 10731132 REFERENCE 12 (bases 1 to 6349) AUTHORS Celniker,S., Carlson,J., Wan,K., Pfeiffer,B., Frise,E., George,R., Hoskins,R., Stapleton,M., Pacleb,J., Park,S., Svirskas,R., Smith,E., Yu,C. and Rubin,G. CONSRTM Berkeley Drosophila Genome Project TITLE Drosophila melanogaster release 4 sequence JOURNAL Unpublished REFERENCE 13 (bases 1 to 6349) CONSRTM NCBI Genome Project TITLE Direct Submission JOURNAL Submitted (20-DEC-2023) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA REFERENCE 14 (bases 1 to 6349) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (13-DEC-2023) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 15 (bases 1 to 6349) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (10-NOV-2022) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 16 (bases 1 to 6349) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (19-OCT-2022) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 17 (bases 1 to 6349) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (20-APR-2020) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 18 (bases 1 to 6349) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (22-APR-2019) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 19 (bases 1 to 6349) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (24-MAY-2018) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 20 (bases 1 to 6349) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (07-DEC-2016) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 21 (bases 1 to 6349) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (07-OCT-2015) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 22 (bases 1 to 6349) AUTHORS Celniker,S., Carlson,J., Kennedy,C., Wan,K., Frise,E., Hoskins,R., Park,S., Svirskas,R. and Karpen,G. TITLE Direct Submission JOURNAL Submitted (10-AUG-2006) Berkeley Drosophila Genome Project, Lawrence Berkeley National Laboratory, One #Cyclotron RoadOne Cyclotron Road, MS 64-121, Berkeley, CA 94720, USA REMARK Direct Submission REFERENCE 23 (bases 1 to 6349) AUTHORS Celniker,S., Carlson,J., Wan,K., Frise,E., Hoskins,R., Park,S., Svirskas,R. and Rubin,G. TITLE Direct Submission JOURNAL Submitted (10-AUG-2006) Berkeley Drosophila Genome Project, Lawrence Berkeley National Laboratory, One Cyclotron Road, MS 64-121, Berkeley, CA 94720, USA REMARK Direct Submission REFERENCE 24 (bases 1 to 6349) AUTHORS Smith,C.D., Shu,S., Mungall,C.J. and Karpen,G.H. CONSRTM Drosophila Heterochromatin Genome Project TITLE Direct Submission JOURNAL Submitted (01-AUG-2006) Drosophila Heterochromatin Genome Project, Ernest Orlando Lawrence Berkeley National Laboratory, 1 Cyclotron Road, Mailstop 64-121, Berkeley, CA 94720, USA REFERENCE 25 (bases 1 to 6349) AUTHORS Adams,M.D., Celniker,S.E., Gibbs,R.A., Rubin,G.M. and Venter,C.J. TITLE Direct Submission JOURNAL Submitted (21-MAR-2000) Celera Genomics, 45 West Gude Drive, Rockville, MD 20850, USA COMMENT REVIEWED REFSEQ: This record has been curated by FlyBase. This record is derived from an annotated genomic sequence (NT_037436). On Oct 19, 2015 this sequence version replaced NM_001259769.2. ##Genome-Annotation-Data-START## Annotation Provider :: FlyBase Annotation Status :: Full annotation Annotation Version :: Release 6.54 URL :: http://flybase.org ##Genome-Annotation-Data-END## FEATURES Location/Qualifiers source 1..6349 /organism="Drosophila melanogaster" /mol_type="mRNA" /db_xref="taxon:7227" /chromosome="3L" /genotype="y[1]; Gr22b[1] Gr22d[1] cn[1] CG33964[R4.2] bw[1] sp[1]; LysC[1] MstProx[1] GstD5[1] Rh6[1]" gene 1..6349 /gene="Tmc" /locus_tag="Dmel_CG46121" /old_locus_tag="Dmel_CG14177" /old_locus_tag="Dmel_CG3280" /gene_synonym="CG14177; CG3280; CG46121; Dmel\CG46121; DmTMC; dTmc; Tic; tmc; TMC; Tmc-L" /note="Transmembrane channel-like" /map="67C2-67C2" /db_xref="FLYBASE:FBgn0267796" /db_xref="GeneID:26067066" CDS 354..6152 /gene="Tmc" /locus_tag="Dmel_CG46121" /old_locus_tag="Dmel_CG14177" /old_locus_tag="Dmel_CG3280" /gene_synonym="CG14177; CG3280; CG46121; Dmel\CG46121; DmTMC; dTmc; Tic; tmc; TMC; Tmc-L" /note="CG46121 gene product from transcript CG46121-RD; CG46121-PD; Tmc-PD; transmembrane channel-like" /codon_start=1 /product="transmembrane channel-like, isoform D" /protein_id="NP_001246698.1" /db_xref="FLYBASE:FBpp0312605" /db_xref="GeneID:26067066" /db_xref="FLYBASE:FBgn0267796" /translation="MQSSADAKREFYKGQRGRRAASQEDHRSYELNDFPLQNQSSDAE SCHQEPHFAHQRSPGIGFDEDGGGGDIDDEESYTISVSAIMQRRASVRGYRGKRGSRS SRRASSPMDHVLDSVERRRSSVYTTSSEEGTNQESTQEQIFENIRLHKEVIQSVKLQP WPIRKKLKLVRQAKTYVARHEGALQERFAMSRSTRDLWARFKILMAARWRHWKRETAS FLTVLIPWELRIKEIESHFGSGVASYFTFLRWLMWVNIMIAIPLVAFVIGPEYFATKH GETDPRKRMSDPEARVAGNLFTFWEFEGYLKYSPMFYGYYSSTSGISTSGYKLPLAYF LTAVLVYIYSFVATLRKMAENSRNSKLSSKDDECVFSWKLFTGWDFMIGHAETAHNRI ASVVVGFKEALLEEAEKKKDNRNWRVILQRILVNILVMGLLGLSGATVVLLVNHSEDL AKHDNWLSRNAVNVTMTLLSFFLPMIFEALGLFENWHPRQQLRLQLARIMILNMLNLY SLMFSFIYKINSKEKPLQMLKLENETNTMELKNLLSSIEALRAMTPTTSLYGESTSDG LFDDSTSTATWGEDGGGLFSTTAAAALISTTVQRLKCYNMTVKCSKLRRNIISGKHLA TTLMVLNLTTPAMVPPTLPTTLPTTFPTTLPTTLPTTLPTALPTTLPTTLPTTLPSTL ATTTATTSSIWSTTEETSPTTTTTSPWTTLPPSTTTTEATTTTERATTTTEATSTTTL KITTAEINSTLSDTTKPLGKSIDTEIPNSTTNSATLSTIPATLNTTNLPLNSTTKLTT TTSTEKPQGEDNFIYTTGEDEGSYDYGSDSTSDAPDNNSYSDITDYSSEPSEIEDFDE QESTDQADDPLAKVLEQLDENETKGRRKRALAESPFFTSKYSRRHRNESAVSAGQPRE TTESVNATPSRWPFNWASFRQTTPRTTTTRRVPSGILTKEEWERLRRLRGRITTTTST STTSTTTRRPRWRYRTTTTELTSTTEEESSTTESSTDSSSPGSTTNAFDSSSSTTEED EYTTTEGSENRPYYVGYVDISEMGSTIYYDGDSEFLEECVITICPKGDDFFGSTTESP DSTTQSSDSKQLTTVKLTPLERKQKRLKEVQLAIKQIQTNLTTMCWETSLGQELSKVI VFDGLMSIVAPLCIDFLRALFVRYVNQNWCWDMEKTFPQYGDFKIAENILTLINNQGQ VWMGIFFSPGLVLINLVKLMIMMYFRSWIVLTCNVPHEVVFKASKSNNFYLSLLLTML FLCVLPVGYAIVWLRPSWHCGPFSEYNRIAEFITNTTRNALPKQLHEPLDYLTSSSTV IPLLLLLILIIYYLVSLTGALREANQDLRTQLQKEREEERKKIFKVPEVKQAEPTATT LTNRWRKVLEASSPVTPTQPPDFDTEEYKNQARKELISRIMKKALRKGSATSDEDSFV RRDDDDTDTEHQDSLPHDEEAKDKRFGLSRLQQIRRTRKPSLVDIVQIAKQERARAGS IVAGTSSSGTGNFPIKETHPKSRFKVEKHERKDRGSMKDKKDTRHRQSPQQQQQPPPY ESPKDNEHDPDTNSRIVSASLLRRHKEQAEGEEPPTTPDAPQTPNSPVEPVEQALEES TPETPTLAKSKFHIVDEKKPPPHEVEDKPLPTPKESGSGGGSLGKFKFRKHKFKSNNV AAVKPEPEVFKFDERSVERSSDVPATHAAEYLNNEPSGTEEQDRSLPSPTPSQGQGHH QRQLSVLSRQGRKKIGNLLALVREAVNLKKDDVEQAGSDESPGPTTPTYLAYTPPPPP SVLSSVSSSTALEMPPTPEPESPTPSAPLHFGSSTSSRAPSKPPKPPMVPASATAPTA TMDDLEELDTAGPITFPRRSDSHRRRTMRQDSQSSIWSDNIPTITISTTGSDECIVDA AAPQNGLPDPRSASPEPTVNIIRIDIENEHEK" ORIGIN 1 cagtctgcgc acaaggctgc tccaaagcgc ttcggcttat aactggctaa atcgggagca 61 aaaagtgcta gcttgtccat taaagggatt ttctttgagg gcactagaag agatgtaaca 121 cataaattgc acagcagtga aattaataaa taagcactta acagcgaagg tcattccgca 181 cgcaaagagt accagtgtga tttgagtaat tagctgtccc ggaacagcac ttgaaaatta 241 gttgagttaa gctgctgccc atccattcgt agaacaactc gggagtcaca tcgcctcatc 301 aactctctgt gacctgggca ccgccatgcg acttggatag aggtggctgg caaatgcaga 361 gcagcgccga tgccaagagg gaattctaca aaggacagcg aggcaggaga gctgcgtcac 421 aggaggacca cagatcctac gaactgaacg atttcccatt gcaaaaccag agcagcgacg 481 ccgagagttg ccaccaggag cctcactttg cccaccagcg ttcgcctgga atcggattcg 541 acgaggatgg cggcggtggc gacattgacg atgaggagag ctacacaatt tccgtatcgg 601 caataatgca gagacgtgcc agtgtgcgcg gctatcgggg caaacgcggc agccggagtt 661 cgcgacgtgc atccagtccc atggatcacg ttctggacag tgtggagcga cgacgctcca 721 gtgtctatac gacaagttca gaggagggca ccaatcagga gtcaacgcaa gagcaaatct 781 ttgagaacat ccgcctgcac aaggaggtca tacagtcggt gaagctacag ccatggccca 841 tccgcaagaa gctcaagttg gtgcggcagg ccaaaacata tgtggcacgc cacgagggcg 901 cgctccagga gcgcttcgcc atgtcacgca gcaccagaga cttgtgggcg aggtttaaaa 961 ttttaatggc ggcacgatgg cgacactgga aacgtgagac ggccagcttc cttaccgtcc 1021 tcattccctg ggagctgcgc atcaaggaaa tcgaatcaca cttcggctcc ggcgtagcct 1081 cctactttac attcctgcga tggcttatgt gggtcaatat catgattgcc attccgctgg 1141 tcgccttcgt cattggcccc gagtactttg ccacaaagca cggcgaaacg gatcccagga 1201 aaaggatgtc cgacccggag gctcgggtgg ccggcaatct tttcacgttc tgggagttcg 1261 agggatacct gaaatattca cctatgtttt atggatacta ttcaagcaca tccggcatta 1321 gcacgtccgg atataagctt cccttagcct atttccttac cgccgttctg gtctacatct 1381 acagctttgt ggccacgttg aggaaaatgg cggaaaactc gcgcaactca aaactttcct 1441 cgaaggacga cgagtgcgtc ttctcgtgga agctcttcac cggctgggac tttatgattg 1501 gacacgcgga aacggcgcac aatcgcatcg catccgtggt cgtgggcttc aaggaggcac 1561 tgctggagga agcggagaaa aagaaggata atcgcaactg gcgggtcata ctccagagga 1621 tactggtcaa tatactggtg atggggctgc tgggcttgtc gggcgctacg gtcgtgctgc 1681 tggttaatca ctctgaggat ttggccaagc atgacaactg gctgagtcgc aatgcggtga 1741 acgtgaccat gaccctgctc tccttcttcc tgcccatgat attcgaggca ctgggtctgt 1801 tcgagaactg gcatcccagg cagcagctgc gtttgcaatt ggctcgcatt atgatcctga 1861 acatgttaaa cttgtactcg ctgatgttct ccttcatcta caagatcaac agcaaggaga 1921 aaccgctaca gatgttgaaa ttggagaacg aaacaaacac catggagcta aagaatctac 1981 ttagttcaat tgaggctctg agggccatga cacccacgac atcgctatat ggtgaaagta 2041 cttcggatgg gctattcgat gactctacat caacggcaac ttggggtgag gatggtggtg 2101 gcctcttttc gaccacagcg gctgctgcct taatctccac caccgtgcag cgtctcaagt 2161 gttacaacat gactgtaaaa tgctcaaagc tgcggcgcaa catcatcagt ggcaagcact 2221 tggccaccac tctgatggtt ctcaacctga caacaccagc catggtgcca ccaactttgc 2281 caaccacatt gcccaccaca tttcccacca cattgcccac cacattaccc actacattac 2341 ctacagcatt gcctaccaca ttgcccacca cattgcctac tacattgccc tccacattag 2401 ccaccacaac ggcgacgact tcaagtattt ggtcaaccac agaggaaaca tctccgacaa 2461 ctacaacgac atcaccttgg accacgttac cgccctcgac aacaaccact gaggcaacca 2521 caacgactga aagagccacc acaaccacag aagcaacgag cacaaccaca ctgaagatca 2581 ccactgccga aataaatagt acactatcag atactacaaa acccctggga aaatctattg 2641 atactgaaat acccaactca acaacgaatt ctgccacttt gagcacaata ccagccactt 2701 taaacaccac taatttaccc ctgaacagca ccaccaaact aactacaacc acatccacgg 2761 agaagcccca gggagaggat aactttatct acaccaccgg agaagatgag ggctcctacg 2821 attatggcag tgattccaca tcagacgctc cggataataa tagctactcc gatataacgg 2881 attactcttc ggaaccgtcg gaaattgaag atttcgatga acaggaaagc acggatcagg 2941 cggacgatcc actggccaaa gtattggagc agctcgatga aaatgagacg aagggacgca 3001 ggaaaagggc attggccgaa tcaccattct ttaccagcaa gtacagcagg cgacatcgca 3061 atgaatccgc tgtctcagct ggacaaccac gagaaaccac tgaatcggtg aatgccacac 3121 ccagtcggtg gccatttaat tgggcatctt ttaggcaaac cacaccgaga accaccacaa 3181 caagaagagt tcccagtgga attctaacca aggaggaatg ggaaagactc agacgactta 3241 ggggcaggat taccacaact accagtacgt ccaccaccag cacaaccaca agaagaccca 3301 ggtggagata tcgaaccacg actaccgaac ttaccagcac caccgaggaa gaatcctcca 3361 caacggagag ttccactgat tcatcgagtc cagggagcac taccaatgcc ttcgacagca 3421 gcagtagcac caccgaagaa gatgaataca ccaccacgga gggatcggag aatagaccct 3481 actatgtggg ctacgtggac atatcggaaa tgggaagtac tatctactac gatggagata 3541 gtgaatttct ggaggagtgt gtgattacca tttgccccaa gggcgatgac ttttttggca 3601 gcaccactga aagtccggat agcaccaccc agagcagcga ctccaagcag ctaaccacag 3661 tgaagctcac tccgctggag cggaagcaga agcgtttgaa ggaagtgcag ctggcgatta 3721 agcaaataca aaccaatctg acgaccatgt gctgggagac ctccttgggc caggagctct 3781 ccaaagtcat cgttttcgat gggctgatgt ccattgtggc gccgctgtgc atcgactttc 3841 tgcgcgccct cttcgtccgg tatgtcaatc aaaactggtg ctgggacatg gagaagacct 3901 ttccccagta cggtgacttc aagatagccg agaacatcct gacgttgatt aataaccagg 3961 gccaagtgtg gatgggcata ttcttctcgc cgggcctggt gcttatcaac ctggtcaaat 4021 tgatgatcat gatgtacttc cgttcgtgga tagtgctcac ctgcaatgtg ccgcatgagg 4081 tggtgttcaa ggcctccaag tcgaacaact tctacctatc gctgctgttg accatgctgt 4141 tcctttgtgt cctgcccgtg ggctatgcga ttgtgtggct gcgtccttcc tggcattgtg 4201 gacccttctc ggagtacaac aggatagctg agttcattac caacaccacg aggaatgctc 4261 tgccaaaaca actccacgaa cccctggact atctgacctc ctcgagcact gtgattccat 4321 tgcttctgct tcttatcctt attatatact acctggtttc gctaactggc gctctacgcg 4381 aagccaacca ggatttgcgc acccaactcc agaaggaacg cgaggaggag cgcaagaaga 4441 tctttaaggt gccggaggtc aaacaagcgg aaccaacggc caccacgctg acaaatcgct 4501 ggcgcaaagt actcgaggcc agctctccgg tgacacccac ccaaccaccc gatttcgata 4561 cggaggagta caagaatcaa gcccggaaag agctaatctc acgcatcatg aagaaggcgt 4621 tgcgcaaggg atccgccacg tcggatgagg attcgtttgt gcggcgcgac gacgatgaca 4681 cggacaccga gcatcaggac tccctgcccc acgacgagga ggccaaggac aagcggttcg 4741 gcctgtcgcg attgcagcaa atccggcgta cccgcaaacc atcgctggtg gacatcgttc 4801 agattgccaa gcaggagcgg gcacgggcgg gatccattgt ggccggaaca agctcctctg 4861 gaactggcaa ttttcccata aaggagaccc atccaaagag ccgcttcaaa gtggagaaac 4921 atgagcgcaa ggataggggc agcatgaagg ataaaaagga caccaggcac agacagtcgc 4981 cacagcagca gcaacagccg ccgccctatg aatcgcccaa ggacaatgaa catgatccgg 5041 atacaaattc aagaattgtc agcgccagtt tgctgaggcg ccacaaggag caggcggagg 5101 gagaggaacc acccactacc cccgacgcac cacaaacacc caactcgcca gtagagcccg 5161 tggaacaggc gctcgaggaa tccacacccg aaactcccac gctggccaaa agcaaattcc 5221 acatagttga tgaaaaaaaa cccccgccgc atgaagtgga agataaaccc ttgccgacac 5281 ccaaggagag tggcagtggc ggtggaagtt tgggcaagtt caagttccgt aagcacaaat 5341 tcaagtcaaa taatgtggct gccgtcaagc cggagccaga ggtgttcaag tttgacgagc 5401 ggagtgtgga aaggagttcg gatgtaccgg caactcacgc cgcagagtac ctaaacaacg 5461 agccatccgg cactgaggag caggatagga gtctgccatc acccactccc agccagggtc 5521 agggtcacca ccagcggcaa ttgtctgtgc tttcccggca gggtcgcaag aagatcggca 5581 acctgttggc cctggttcgt gaagccgtca atctcaaaaa ggacgatgtg gagcaggcgg 5641 gctcggatga gtcgccgggt cccacaacgc ccacctactt ggcctacaca ccgccaccac 5701 caccatcagt attgtccagc gtgtccagtt cgacggcctt ggaaatgcca cctactccgg 5761 aaccggaatc tccaacgccc agtgcaccac tgcactttgg cagcagcaca tcgtctcgtg 5821 cgccttccaa gccaccaaag cctccaatgg ttcccgcatc cgccactgct ccaacggcca 5881 ccatggatga cctggaggaa ctggacacag ccggtcctat tacatttccc aggcgcagcg 5941 attcccatcg ccgtcgcact atgagacagg attcacagag ctccatttgg tcggataata 6001 tacccactat tactataagc accaccggca gcgatgagtg cattgtggac gcagctgctc 6061 cacaaaatgg gcttcccgac ccgcggagtg cttccccgga gcccacggtc aacattataa 6121 ggattgacat tgaaaatgag catgagaaat gatgtaccaa gcgaagaagt gccttgaaca 6181 ccagattgtc ttcttgaata aacatattag cattcttcct acttcactta ctatttagct 6241 tgaatcttgt tcttcagaat ataaaaagaa acctttcgat ccttacgaaa taatgatgtt 6301 tcattcatta gcttatttcc gtaataaata aaaataaacc actctaaat //