Dbfetch
ID OX175561; SV 1; linear; genomic DNA; STD; HUM; 11639 BP. XX AC OX175561; XX PR Project:PRJEB53990; XX DT 07-JUL-2022 (Rel. 144, Created) DT 14-APR-2023 (Rel. 144, Last updated, Version 3) XX DE Homo sapiens, MICA gene for MHC Class I chain-related gene, cell line DE DKMS-LSL_ID20694462_MICA_1, allele MICA*018:new XX KW . XX OS Homo sapiens (human) OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; OC Homo. XX RN [1] RA Albrecht V., Schmidt H. A., Klussmeier A., Lange V., Putke K.; RT ; RL Submitted (05-JUL-2022) to the INSDC. RL DKMS LIFE SCIENCE LAB, Research & Development, St. Petersburger Str. 2, RL Saxony, 01069 Dresden, Germany XX DR MD5; 0379ece1e158248e94ed6995cf43db64. XX FH Key Location/Qualifiers FH FT source 1..11639 FT /organism="Homo sapiens" FT /mol_type="genomic DNA" FT /cell_line="DKMS-LSL_ID20694462_MICA_1" FT /db_xref="taxon:9606" FT exon 1..86 FT /gene="MICA" FT /allele="MICA*018:new" FT /number=1 FT CDS join(17..86,7028..7282,7557..7844,8432..8710,8811..8942, FT 11494..11621) FT /codon_start=1 FT /transl_table=1 FT /gene="MICA" FT /allele="MICA*018:new" FT /product="MHC Class I chain-related gene" FT /function="antigen presenting molecule" FT /protein_id="CAH8699381.1" FT /translation="MGLGPVFLLLAGIFPFAPPGAAAEPHSLRYNLTVLSWDGSVQSGF FT LTEVHLDGQPFLRCDRQKCRAKPQGQWAEDVLGNKTWDRETRDLTGNGKDLRMTLAHIK FT DQKEGLHSLQEIRVCEIHEDNSTRSSQHFYYDGELFLSQNLETEEWTMPQSSRAQTLAM FT NVRNFLKEDAMKTKTHYHAMHADCLQELRRYLKSGVVLRRTVPPMVNVTRSEASEGNIT FT VTCRASGFYPWNITLSWRQDGVSLSHDTQQWGDVLPDGNGTYQTWVATRICQGEEQRFT FT CYMEHSGNHSTHPVPSGKVLMLQSHWQTFHVSAVAAAAIFVIIIFYVRCCKKKTSAAEG FT PELVSLQVLDQHPVGTSDHRDATQLGFQPLMSDLGSTGSTEGT" FT intron 87..7027 FT /gene="MICA" FT /allele="MICA*018:new" FT /number=1 FT exon 7028..7282 FT /gene="MICA" FT /allele="MICA*018:new" FT /number=2 FT intron 7283..7556 FT /gene="MICA" FT /allele="MICA*018:new" FT /number=2 FT exon 7557..7844 FT /gene="MICA" FT /allele="MICA*018:new" FT /number=3 FT intron 7845..8431 FT /gene="MICA" FT /allele="MICA*018:new" FT /number=3 FT exon 8432..8710 FT /gene="MICA" FT /allele="MICA*018:new" FT /number=4 FT intron 8711..8810 FT /gene="MICA" FT /allele="MICA*018:new" FT /number=4 FT exon 8811..8942 FT /gene="MICA" FT /allele="MICA*018:new" FT /number=5 FT intron 8943..11493 FT /gene="MICA" FT /allele="MICA*018:new" FT /number=5 FT exon 11494..11639 FT /gene="MICA" FT /allele="MICA*018:new" FT /number=6 XX SQ Sequence 11639 BP; 2382 A; 2971 C; 2798 G; 3488 T; 0 other; tggcgacgtc ggggccatgg ggctgggccc ggtcttcctg cttctggctg gcatcttccc 60 ttttgcacct ccgggagctg ctgctggtga gtggcgttcc tggcggtcct cggcggagcg 120 ggagcagtgg gacgtttccg ggggtcgggt gggtagcggc gagcgctgtg cggtcagggc 180 ggggctcctg tgccctgtcg gtggcgcagg gagctggacg cggcccgtta ccgccacact 240 tcagccctgc ttccccgtca cttttcagtc ctcctcggga tcgcgcatca cctgcacttt 300 ctggtctcct cctgctcttt ctctcctcgc gtctcctccg cttcctctca cttttcggac 360 aaaccagtcc ttctgaggcc catgggttcc cgggctgcct ccggggctgc tcctgtgaat 420 ggcattcgag tgcccttcca gcgcggccac tgaagcagcc acaacccccg gtgcttgggg 480 cggctctcag gtccctgaag tcctgtcctc tcccggagcc gacgtgttct cagctcctgg 540 gccgcagctc ctggagtagg ggccctcctt tctcgggacc cggaggtggt gcttcctgct 600 gctgtgggga ctgtgggggg tcctgactct caagctgagg ggttggagtc tgcaggctcc 660 gggcagagga ttcttcctgc gacttctctc atccccagct cattctcccc tcgcctctgg 720 ctccgagggt cctctcctct ctctcatccc acccctacta atgaccagtg atctaaggac 780 accagattcc ctctcacctc ctccctgccc atctcagggc ccgctgagtc cttttgccct 840 cccagctccc tgctacccct tcctgtgtgc tgttctctga tccatttcta gggtgtcctc 900 tgccctcatc ccctgtcccc gccaccgaag gtccctcctg caccccttat gggcctttcc 960 tacaagcagc cttcacccag tgctgcccct atgcctcccc gttcccaaat gtccctgact 1020 ctaactttct ggtgctgcct tttatccggg ggggtcttcc ctccatccca ctcccctcca 1080 gacccccaag gggaaccctg atgctaatgg cagttgggcc ttaggcaggg cgcagggcag 1140 cgcagatgcc ccctcccctc cagtgcagat gcctgctctg gaccctgcct cattgtggcc 1200 ccttccccac tccttcatcc tcagcctcac cctcttgagg accccaccct ccagcccaca 1260 ggtgctggac catccctccc tggtccctcc gcccctctcc accttgggac cttgtgctgc 1320 tcctatctct tgcccagctg ccttgggccc tcagcacgtt ctcatctttc agtgggaaag 1380 tgggagtgct ggagcatatg acagtgctga gcatctttcc caagccccac cctcccccag 1440 agcaccctcc cctcctgtcc tcaccctacc ccaagttctc ccacagtcac tcctgcccca 1500 tgctcatgcc gccctccagt tcttgctctg cccatctccc ctccccaacc cagacctaaa 1560 acaggctgtt gggccaactg ttccttgacc ttccttcttt tcttttggtt ccttgacccc 1620 agtgggctct cactccccac accgcatatc taaaatctgt tttgcctgct cttggggtgc 1680 cactgctccc cctccagcat tactcctttt ggcaggtcct tcctcaggct gagaatctcc 1740 ccctctacct tggttttctc tctctggcca gcacccccac cccttgcttt gtttttaatt 1800 tttaactttt gtttgggtac gtagtagata tatatgtata tatttatggg gtacatggga 1860 tattttcaca caggcctaca atatgtaata atcacatcag ggtaaatggg ttatatcaca 1920 acaagcattt atcctttctt tgtgctacaa acaatcccat tatgctcttt cagttatttt 1980 taaatgtaca ataaattatt gttgactgta ctcaccctgc tgtgctatct actagatctt 2040 attcattcta attatatttt tgtacccatt attaaccatc cctgctcccc cactccccac 2100 tacccttctc agcctctggt aatcatcatt ctattgtctc tccccatgag gtccattgtt 2160 ttaaattttg gctgccacaa ataagtgaga acatgcaaag tttgtctgtc tgggcctggg 2220 gcttatttca cttcacagga tgacctccag ttctttgcaa atgacacgat ggctgaatag 2280 ttctccacat acacatgtac accacatttt ctttatccat gcgtctgttg atggacactt 2340 agattgcttg cagatcttgg ctactttgaa tagtgctgca ataaacatgg aaaagtagat 2400 agctctttaa tataccgatt tcctttcttt ggagtatatg cctaacagtg ggagtgctgg 2460 agcatatgac agctctattg tatttttagt ttttggaaga acctccacat tgtttcccat 2520 agtggttgta ctagtttacg ttcccaccaa cagtgtacat cctcaccagc attccttatt 2580 tctacatcct cgccagcatt ccttattgcc tgtcttctgg ataaaagcca gtttatctgg 2640 ggtgggatgt tatctcgtag gagttttgat ttgccttcat ctgttgacga atgatgttga 2700 gcaccttttc atatacctgt ttgccattta tatgtcttct tttgagaaat gactattcag 2760 atcttttctc atttttaaat tggattatta tatttttttt cctatagttg ttcgagctcc 2820 ttatatgttt cagttactga tcctttgtca gatgaatagt ttgaaaatat tttctcccat 2880 tcttggatgg tctcttcatt ttgtttattg tttcctttgc tgtgcagaag cctttttact 2940 tgatatgatc ccatttatgc aattttactt tggttacctg tgcttgtggg gtattacttt 3000 aaaaatcttt gcccagtcca atatcctaga gagtttcccc aatgttttct tgtatagttt 3060 catagtttga ggtcatagat ttacatcttt aatccacttt gatttgattt ttgtatatgg 3120 tgaaagacag ggtctagttt cattcttctg cataaggata tctagtttcc ccagcaccat 3180 ttttgaagag actctccttt gccaatgtgt gttcttggta cctttgttgg aaatgagttt 3240 actgtagatg tatggaattg tttctgggtt ctctattctg tttcattggt ctgtgtgtct 3300 gtttttatgc cagtatcatg ctgttttggt tactgtagct ctgtagtata atttgaagtc 3360 agataatgtg attcctctag ttttgttcat tttgctcagg atagctttat ctattctggt 3420 ttttttgtgg ttccatatgt attttaggat tatttttatt atttctgtga agaatgtcat 3480 tagtgttttg atagggattg cattgaatct gtagattact ttgggtagta tggatatttc 3540 aacaaaactg attcttccaa tccatgaacg tggactatct tttccatttt ttgtgtcctt 3600 caattttttg catcagtgtt ttttgttttt ggtttttgag atggagtttc actcttgttg 3660 cccaggctag aatgcaaggg tgtgatcttg gctcaccgca acctccgcct cccaggttca 3720 agctattctt ctgcctcagc ctcccaagta gctgggatta caggcatgtg ccactgtgcc 3780 tggctaattt tctattttta ttagagatgg ggtttctcta tgttggccag gctagtcttg 3840 aactcctgac ctcaggtgat ccacctgcct cggcctccca aagtgctggg attacaggca 3900 tgagccacca cgcccagcca catcactgtt ttatagtttt tattggagag gtctttcact 3960 tcttcagtta ggtttattcc tcagtatttt attttatttg tagctattgt aaatgggatt 4020 cgtttcttga tttctttttc agattatttg ctgttagcac tgatttttgc atgttgattt 4080 tgtatcctgc aactttactg aatttgttct tcagttctaa tggttttttg gtggagtctt 4140 taggtttttc caaatatcag accacatgat ctgcaaacaa ggataatttg acttcttctt 4200 ttccagtttt aatgcccttt ctttctttct cctgtctgat tgctctagtt aggatctgca 4260 gtactgtgtt gcataactgt ggtaaaatta gtcatccttg tcttattcca gatcttagag 4320 aaaaggcttt cagttttccc ccattcagta tgttactagc tgtgagtttg tcatatatgg 4380 cttttattat attgaggtct gttccttgta tacttagttt tttgagagtt tttatcatga 4440 agggatgttg aatttatcaa atgctttttc agtatcaatt gaatgatact ggcttttgtc 4500 ctttattctg ttgatatgac gtattacatt gattgatttg tgtatgttaa atcatccttg 4560 catacctgga atacattcca cttgctcata aagaatgatc ttttttaatg tattgttgaa 4620 tgtggtttgc tagtatttcc ttgacgattt ttgcatcggt gttcatcagg gatataggcc 4680 tgtagttttc ttttttatga tgtgtctttg cctggttttt gtatcaggat attcctggct 4740 ttgtaaaatg agtttggaag tattccctcc tcctctattt ttcagaacag tttgaatagg 4800 actgacatat gttgttcttt aaaagtttaa ttgtggtaaa ttatacatta cataaatttt 4860 actgttttaa ccacttttaa gtgtatactc ggtggcatta gatacattca catttttgtg 4920 caacccaaaa ctctgtgccc attaatcggt aactccccat tcctccctac ctctggcccc 4980 tggtaaccac cattctactt tttgtttcta tgaatttgac cactctaggt acctcattta 5040 agcagaatca tgtaatgttt gtctttttgt ttctggctta tttcacttat aatatttttg 5100 aggttcggtg ggcacagtgg ctcacgcctg gatttccagc actttgggag gctgaagcag 5160 gtggatcacc tgagtttcgg agttcgaaac cagcctggcc aacatggtga aaccccatct 5220 ctactaaaaa taataaaagt tagccgggcg tgatggcggg tgcctgtaat cccaactact 5280 tgggaggctg aggcaggaga atcgcttgaa tccgggaagt ggaggttgca gtgagctgag 5340 atcaggccac tgcactccag cctgggcaac aagagtgaaa ttccatctcc aaaaaaaaaa 5400 aataagacaa taataataat aatatttttg aggttcatcc aagttgtagt atgggtcaga 5460 atttcattcc ttttaaggat ggataatact cattatatgt atgtaccaca tcttggttat 5520 ccatccctca gacaacggac acttgggtta cttctacctt ttggatattg gcaaatattt 5580 catttccttt gggtatatat ttatttcctt tgggtatttc ttttgggtat atatccagaa 5640 atagaagcag tacacagggg cttcattttc tctgtctctt tgccaacctt gctctgtgtg 5700 tgtgtgtgtg tgtgtgtgtg tgtgtgtgtg tgtgtgtagg tgtgtgataa cagccatcct 5760 gattggtttc aggtggcatc tcattgtggt ttggatttcc attttcctaa tgagtgctga 5820 tattgagcat cttttcatgt gtttgttgat catttgtaat tttctttgaa gaattggcca 5880 tttaagtctt ttgcccattt tttcccccac atagcttctc atggctactt tgcccatttt 5940 ttagtgggtt gactgttttt gttgtttttg tcagactttt ttatatattc tggaaactaa 6000 tctcttatca gatatatgac ttgcaatatt tatttcattt cggggttgat tgctttttca 6060 ctctgattgt gccctttgat gcatagatgt tttgaatttt catcagtcta ctttgtcagt 6120 tctttctatt ctatctgtgc tttggtgtca tatccatgaa agcactgtca aatcctatgt 6180 catgaacatt atccccaatg tttgcttcta agaaattttt aggttttagt tcttgagtgt 6240 agagtttagg tctttgattc attttgagtt aatttttgta tatagtgcaa attaagagtc 6300 caattttatt ttaacacccc ctgcccccag aactatttgc tgaaaagatc aactgactct 6360 ttgtcacctg ctcaccccag tggacactag ctgttccatc caattgctgt cctggggcct 6420 tgtcatgcca ctcttccact ttgaacccaa gcccacaccg ttgctcccct ctgggatact 6480 gaccccacta taaacttctc tggggctaca accttcctac cccttgtgcc tcatgaccac 6540 cccctccctt gtccccacca tgcccatgat gagtctcttc tcgaggcagc tccccttgcc 6600 tccatctcac cctcacctat gcaccacagc cacactggac atgggtccct ctgagcctga 6660 gtcccttccc attcccacca tcccctctgg caagaccttc cttccaccac cttcatgctc 6720 ctccctcgcc cctgcagggc agcctctccc cttggcccct attcccttag ggggcttgtg 6780 gccacccagt ccttgcacct ggcctacaag tttgccatct tcattccccc ttcttctgtt 6840 catcagcccc ctcctctatc ctcccaccct cacagttttc tttgtatatg aaatcctcgt 6900 tcttgtccct ttgcccgtgt gcatttcctg cctcctcagg aaggttggga cagcagacct 6960 gtgtgttaaa catcaatgtg aagttatttc caggaagaag tttcacctgt gatttcctct 7020 tccccagagc cccacagtct tcgttataac ctcacggtgc tgtcctggga tggatctgtg 7080 cagtcagggt ttctcactga ggtacatctg gatggtcagc ccttcctgcg ctgtgacagg 7140 cagaaatgca gggcaaagcc ccagggacag tgggcagaag atgtcctggg aaataagaca 7200 tgggacagag agaccagaga cttgacaggg aacggaaagg acctcaggat gaccctggct 7260 catatcaagg accagaaaga aggtgagagt cggcaggggc aagagtgact ggagaggcct 7320 tttccagaaa agttaggggc agagagcagg gacctgtctc ttcccactgg atctggctca 7380 ggctgggggt gaggaatggg ggtcagtgga actcagcagg gtggtgagcc ggcactcagc 7440 ccacacaggg aggcatggag gagggccagg gaggcgtacc ccctgggctg agttcctcac 7500 ttgggtggaa aggtgatggg ttcgggaatg gagaagtcac tgctgggtgg gggcaggctt 7560 gcattccctc caggagatta gggtctgtga gatccatgaa gacaacagca ccaggagctc 7620 ccagcatttc tactacgatg gggagctctt cctctcccaa aacctggaga ctgaggaatg 7680 gacaatgccc cagtcctcca gagctcagac cttggccatg aacgtcagga atttcttgaa 7740 ggaagatgcc atgaagacca agacacacta tcacgctatg catgcagact gcctgcagga 7800 actacggcga tatctaaaat ccggcgtagt cctgaggaga acaggtaccg acgctggcca 7860 ggggctctcc tctccctcca attctgctag agttgcctca cctcccagat gtgtccaggg 7920 aaaccctccc tgtgctatgg atgaaggcat ttcctgttgg cacatcgtgt cctgattttc 7980 ctctattgtt agagccactg gataaagaca gtgggtcagg gactggacca tccagtgttg 8040 taatcagggc aagtagagga ccctccgaca gaatcctgag cctggggtgg gtgtcaggca 8100 ggagaggaag gcttcagggc cagggctgcc ccctctgcct cccagcctgc ccatcctgga 8160 gagttccctc ctggccccac aacccaggag tccacccctg acatccccct cctcagcatc 8220 aatgtgggga tcccagagcc tgaggccaca gtcccatggc ccatcctcct gccagcctgg 8280 aagaactggg ccccagagtg aggacagact tgcaggtcag gggtcccaga gggcttcagc 8340 cagagtgaga acagtgaaga gaaacagccc tgttcctctc ccctccttag aggggagcag 8400 ggcttcactg gctctgccct ttcttctcca gtgcccccca tggtgaatgt cacccgcagc 8460 gaggcctcag agggcaacat taccgtgaca tgcagggctt ctggcttcta tccctggaat 8520 atcacactga gctggcgtca ggatggggta tctttgagcc acgacaccca gcagtggggg 8580 gatgtcctgc ctgatgggaa tggaacctac cagacctggg tggccaccag gatttgccaa 8640 ggagaggagc agaggttcac ctgctacatg gaacacagcg ggaatcacag cactcaccct 8700 gtgccctctg gtgagcctag ggtgaccctg gagagggtca ggccagggta gggacagcag 8760 ggatggctgt ggctctctgc ccagtgtata acaagtccct tttttttcag ggaaagtgct 8820 gatgcttcag agtcattggc agacattcca tgtttctgct gttgctgctg ctgctatttt 8880 tgttattatt attttctatg tccgttgttg taagaagaaa acatcagctg cagagggtcc 8940 aggtgagaaa agcgggcagt ttctggagat ggtaaggccc ctgtctgggc agtagggtcc 9000 cctcattgct cctgcaaaga taggcatgtt ggtgacaagg cttctgtaac aggggatgaa 9060 agttggggaa tttgggaagg gaatgggggc agcatctcca tctacaccta taagtgctgc 9120 ccaagcgagg gtcaaacgcc cagctgtggc atcttcctgc tgcaggtgag gagtgggcag 9180 cagggagggc tgcggcgcct gctctgtccc catcccggtc tctgtgtctc ttggactcac 9240 tagggcgcat ccaggtgggg tgagctggga atcacgtgct gaatgctgag gacctggatg 9300 atcacggcct cagagggagc aaatagtaaa ggcagctgtg atctggggag ggccagaaac 9360 tggagaggaa tctgaggaga ggcggtgccc ctattccctt cctctctgca tccctctccc 9420 ctgtttctcc agccatcggg gcggacaccg agaaaaagac ctatgaggcc cagcctgggg 9480 gccctgcctg tttagccctt tggagacccc ttgtaacagg gagggtcctg agcacacatg 9540 gccatctctg tccacttttc agctccccat gcacctcctc caggagcttt cttggggttg 9600 tcgtgtcctc tgcaccattc gaggccctac tctttccagg ttcccacagc ctggcctccc 9660 tgagtttctt gcagatgaga tggatgagta gataagcaga tgtccctggg ccatttgagg 9720 agtggggccc agcccctcat cagggcagct gtggtccctg ttttcatcct acctccgagt 9780 gttttcttct ccagtccctg agggacacag tcctcagggc ccatgttttt ggggctttaa 9840 tctgtgctct gtggcctcac cttgccctcc ctgagccaat ttccctttct aaaggtggtc 9900 actgcctggt aagtttggag taagggacgg tcagaatcat ttcccctaca gtcaggttgt 9960 ttgatggggg atgaaaagag acagcaggaa gttttgtgtt tctgcaaaga cagaagcagt 10020 tcaggggaca gtaagaggct ggggtgtcca ggagggtgtg tctggcagta gggtcgctgg 10080 tttctcatcc ttgaacctaa ttgcactgtc agtcggcccc tcaggcctga gcagatggga 10140 aggtttgtcc cctgccctgc agtaagaggg ccctgtccag gaggcaccca caacaggggc 10200 agtgcaggtc tgtggtcgct cctgctctca cctgtggtgt ctcccgtaga gggattatca 10260 gttctggttc cctgtgggca ggaatggttt cctcataggt cactggagtt ttggccagga 10320 aaagagtatg aagttcatgt gccagtttct caaaattcct gctttcaatg ttgatgtcaa 10380 gcaaagatat tcgtaatttc agctctataa tcttaatagg atttcctcta atattgtaaa 10440 gcatcttata tgaaacagga acacaaattt ctcaaaattc ctgcgatgtc caataaagat 10500 tttcataatt tcggctctcc aatcttaata ggatttccta atactgtaaa gcatattaaa 10560 tgaaacagga actcaaattt ggagccccct ctccaggagg ttctgtgtgg agatggtggc 10620 tgtggcagtg gcagttccca ggtgcagagg gtgggcagag gcagcctcag gctaaggggt 10680 ctcccctact ccacatggag aaaatccctt gtaggttgca agggcagtgg ccgggtggaa 10740 tccctgctag ggacagagca ggaaggcctc gccgcctcac caagcagcag ccctggggtg 10800 gagctgcgtt tccagggtta agcggaccag gcaggagcag tggttactca acagcaggtc 10860 acaggcttgg gttgtgaggg tcaggagagg ccaggcctcc tcgagcaagg tgggggtccc 10920 agggtcaggt caggtgcaga tcctgtggca gccacgtctt tccatgctgg gcctgctggg 10980 ccccccaggc tttctgatgg ggtccccagt taggagctgc ctgctcaggg ctgggagggg 11040 aggagcgctg agctgcagat agagggcaga gcccacagtg ggcagggcct gccctggtgt 11100 gtaggtgcct ctgcaggaga ggagggcctg gggactgaga gcaagggtca gggcctctct 11160 ttgaggaggc ctctcactgt aacaggactg gtcaggcctg agaggaggtc actgggttcc 11220 ctcttgggtc ttgtccttta gtcttggggc cctttccctc cctgcacgat gagtggtggg 11280 cacagggcag gggctgatgt tgatggagtg atgggaggga actggtaggg gctgggaaaa 11340 gcaaggaggg aggaagaaaa aagtgggggc ctcatcttcc ctcagagaaa gggcgaatct 11400 ggttttggag caactgaaga gagaaaagtc cccagggaat aaacacaaca ctgcacccag 11460 tggagcattt acccgtttcc ctcttttctc cagagctcgt gagcctgcag gtcctggatc 11520 aacacccagt tgggacgagt gaccacaggg atgccacaca gctcggattt cagcctctga 11580 tgtcagatct tgggtccact ggctccactg agggcaccta gactctacag ccaggcagc 11639 //