Dbfetch
ID OV725489; SV 1; linear; genomic DNA; STD; HUM; 10904 BP. XX AC OV725489; XX PR Project:PRJEB50369; XX DT 14-MAR-2023 (Rel. 144, Created) DT 15-MAR-2023 (Rel. 144, Last updated, Version 1) XX DE Homo sapiens, HLA-DRB1 gene for MHC class II antigen, cell line DE DKMS-LSL_ID19577934_DRB1_1, allele HLA-DRB1*15:new XX KW . XX OS Homo sapiens (human) OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; OC Homo. XX RN [1] RA Albrecht V., Schmidt H. A., Klussmeier A., Lange V., Putke K.; RT ; RL Submitted (24-JAN-2022) to the INSDC. RL DKMS LIFE SCIENCE LAB, Research & Development, St. Petersburger Str. 2, RL Saxony, 01069 Dresden, Germany XX DR MD5; fa4850bb54791f1f088269ee9bb2fc5a. XX FH Key Location/Qualifiers FH FT source 1..10904 FT /organism="Homo sapiens" FT /mol_type="genomic DNA" FT /cell_line="DKMS-LSL_ID19577934_DRB1_1" FT /db_xref="taxon:9606" FT exon 1..151 FT /gene="HLA-DRB1" FT /allele="HLA-DRB1*15:new" FT /number=1 FT CDS join(52..151,5416..5685,7956..8237,8938..9048,9524..9547, FT 10690..10703) FT /codon_start=1 FT /transl_table=1 FT /gene="HLA-DRB1" FT /allele="HLA-DRB1*15:new" FT /product="MHC class II antigen" FT /function="antigen presenting molecule" FT /protein_id="CAH1408504.1" FT /translation="MVCLKLPGGSCMTALTVTLMVLSSPLALSGDTRPRFLWQPKRECH FT FFNGTERVRFLDRYFYNQEESVRFDSDVGEFRAVTELGRPDAEYWNSQKDILEQARAAV FT DTYCRHNYGVVESFTVQRRVQPKVTVYPSKTQPLQHHNLLVCSVSGFYPGSIVVRWFLN FT GQEEKAGMVSTGLIQNGDWTFQTLVMLETVPRSGEVYTCQVEHPSVTSPLTVEWRARSE FT SAQSKMLSGVGGFVLGLLFLGAGLFIYFRNQKGHSGLQPTGFLS" FT intron 152..5415 FT /gene="HLA-DRB1" FT /allele="HLA-DRB1*15:new" FT /number=1 FT exon 5416..5685 FT /gene="HLA-DRB1" FT /allele="HLA-DRB1*15:new" FT /number=2 FT intron 5686..7955 FT /gene="HLA-DRB1" FT /allele="HLA-DRB1*15:new" FT /number=2 FT exon 7956..8237 FT /gene="HLA-DRB1" FT /allele="HLA-DRB1*15:new" FT /number=3 FT intron 8238..8937 FT /gene="HLA-DRB1" FT /allele="HLA-DRB1*15:new" FT /number=3 FT exon 8938..9048 FT /gene="HLA-DRB1" FT /allele="HLA-DRB1*15:new" FT /number=4 FT intron 9049..9523 FT /gene="HLA-DRB1" FT /allele="HLA-DRB1*15:new" FT /number=4 FT exon 9524..9547 FT /gene="HLA-DRB1" FT /allele="HLA-DRB1*15:new" FT /number=5 FT intron 9548..10689 FT /gene="HLA-DRB1" FT /allele="HLA-DRB1*15:new" FT /number=5 FT exon 10690..10904 FT /gene="HLA-DRB1" FT /allele="HLA-DRB1*15:new" FT /number=6 XX SQ Sequence 10904 BP; 2845 A; 2193 C; 2646 G; 3220 T; 0 other; gagtgagact tgcctgcttc tctggcccct ggtcctgtcc tgttctccag catggtgtgt 60 ctgaagctcc ctggaggctc ctgcatgaca gcgctgacag tgacactgat ggtgctgagc 120 tccccactgg ctttgtctgg ggacacccga cgtaagtgca cattgcgggt gctgagctac 180 tatggggtgg ggaaaatagg gagttttgtt aacattgtgc ccaggccatg tcccttaaga 240 aattgtgacg ttttcttcag agattgccca tctttatcat tggatcccaa attatttcct 300 ccataaaagg agcttgggta cttgccctct tcatgagact tgtgtaaggg gcctttgcac 360 aaatcatttc ttttcaaatc tccaccaata aaacctttgc atcacatgtc ctcagggtct 420 ttagaggatt tagaaataag gattctaaaa taaattcccc atacagcact tccctttatt 480 atgttgactt atgtcagaca aaaggaggtt cttactgaaa attttgtggg agtcaaggga 540 attcaaaggg tctctcctag acgatccagt gttaggttcc ccacaggacc tttggtgttg 600 gccatagtcc tcatatgtga ggatggaccc agtggcctcc ccattatctc ctttcttttc 660 ttgctgaact ccaatgttta taaggcctgt atccctgtag tgtatgtagg ttctctgaca 720 gaagttatac ttagtgctct tcctttcttg tggggaaaag tccctggaac tgaagctgag 780 attgttaata cttggagtca ccttacagat acagagcatt tatgaggtat tctttggtgc 840 ctaaagaact taaggcatcc tctgaaaaac tagcccaggt tcgtgttcat tatgaatctt 900 ttttaacctt tctgtacttg tttctcttgc atctcctatg tgctctaact agacatgaca 960 gaagagattt aactaatgta taaattatat gaaattctat tttttaagtc aaaaataatc 1020 aactatcaga aatttaataa tgttcaaact atatactctg tgtggggtta ccgagatgat 1080 gtgaacattg ttcacgtctc atagggctga aagtcaatgg gcaagtcttg ggaactcatt 1140 gtcttactgg ggtcttgtcc taaatttcct aggttcaccc atcatgccct cagctttcct 1200 taactagcca tgtctgctta cctcttcctc cagtttctat ttttccccag ctatgttgtc 1260 atcatttcca gaaatctcta aagcttgcac agaaccttag cactatgaga ttcattgaaa 1320 gagacttttt ttctcttttt gaggtagggc ctggctctgt cacccagtct atagctcagt 1380 ggtgtgatcg aggctcactg caacctctgc cacttatgct caagtgatcc tccctcctca 1440 ggctccagag tagctgggaa tacaggcagg caaccacgcc cagctaattt ttgtaatttt 1500 ggtagacatg agattttgcc atgttgccca ggctggtctt gaactgctgg actcaagcaa 1560 tcctcctgcc ttggcctccc aacatgctag gattatagat gtgagacact gtgcccaggc 1620 aaaagagatg actcttaata aaaaaatttc ctttttctta aatcactgtt tctttatctg 1680 tgaattcttc ttccaactag aaggaggaga aaaaagaagt ttgcctgtat ttatcactgg 1740 gaggagaagg ggtctagtgt gacattaaaa tgaaagagtg ctggagcttg agccccttct 1800 tgctttccag gatccctaca gtgatcagtt cccataccct ggtttattca tgtaaaccac 1860 acttattttt ctcagcagct actctttact gggctccatt ctaggttcaa atcattctat 1920 ttgattaagt tagagagcgt ccctactctc atggaagtta cacaagagta gaggagacag 1980 acactaaccc aataagcatt taacaaagaa gataatgtta gagagtcata gtgcactgaa 2040 gaaaagacat caggtttgtg aaaaagagag acatggattc acctacttta gttcatatgt 2100 tagggagctc cacctgagaa agtgacattc agctgagaca acaaaataag tagacagtcg 2160 tgaagatcta agggatgaaa gttccaggga gaccgaatcg ggggaaagcc ctgatgtgtt 2220 aaattatgtg gagggagaga aagaaagcta gaggggctga tgtatagaaa gcaaggaaat 2280 ggagaggcag aagatgaggg taggacacag agaggaattc aggagcctca tcattatagg 2340 ctctgatgtc cacagtaaaa aaaaattaaa ttttattatt tatttatttg tttgtttatt 2400 ttattttatt ttgtgatgga gtctctctct gttgcccagg ctagattgct gtggcacaat 2460 ctcggctcac tgcaacctcc gcctcctggg ttcaagcgat tctcctgcct cagcctcccg 2520 attagctggg gccacaggcg catgccacca cacctggcta attttttgta tttttagtag 2580 ggatagggtt tcaccgtgtt agccaggatg gtctcgatct cctgacctcg tgatccgccc 2640 gccttggcct cccaaagtgc tgggattaca ggcgtgagcc actgcgcccg gcctatattc 2700 aatgtttaaa actaattcta gctactctgt ggggattgga ttgttggggt tcactagtgg 2760 ttaggaagac tatttaggag cacagcaggg aattcttcag ggaaaacagg tttgtggctt 2820 catggagtgc attagtgata aagatggtga aaaagataaa gtggacagac ttggcatgta 2880 tttttgctta gcttgttaat gaattactgt aaagggggta gaacaatcaa gcttattcct 2940 aaggattttc ttttgacaaa taaatgggtg gtagtgttgt ttattgagat aggaaaaact 3000 atgggaggaa atgatttgaa gtgggtggtt tgaaataaaa gttttgttta aatatgagat 3060 gattgattga catttatgtg gagaaatccg aaggtcaatg gcatttaaga gactcatggt 3120 gaggccaggg cttcaggtat ttatgttggc agcagcaata cgtgtagtgt gttaaattcc 3180 agggcgtgga agaggataca tagggagatg gattgtgtga agaaaaaaga acagggcaca 3240 ggccagcaaa gggggctgag aaagagccca aggatgctgg agaaaaacca agagaacatc 3300 atgtgtgtaa gtccaggaaa atagattatt ttcaaggaga agggagaggc caattgtggt 3360 gagtaccact aagaggaggg gcaagtgaga atatgataga gaagcaagtg ctgggtttgg 3420 tggagtcgat atttgcagtc aatggagcat ccaggtagga aactggattg gaccatttga 3480 agagtgagta aaagtgagga cgaggttaag gttgactgtt ttgagtagag agcttcaggg 3540 aaggattgtt ctctgggttc agggagccag ctgaacctaa aggaaaaggc taaagaagct 3600 gaagagaagg aggaggacct gtgaaccaga gatgctcagt cattattagc gaggaaatac 3660 ggagagcccc tgtgtgcagt ggtgactact catgcaaaat gtcacacagc caatatttaa 3720 cacagccagt atttcacaca gccaatattt attagtgaca tagcatatac cagttattac 3780 tctaggtcat gagaatggag tgataaataa aatgaatcca gtcgccatca ctatatgcca 3840 tgtaacattt tgcaatgact gtgtatcagg cctatgaatt tcagtattca atttcaataa 3900 tgatcctgtt gtatctgtgg tatttaaaaa catatacatc tctggaatct aaaattgaga 3960 ggttataagt aacacccagt attacaaatt tagtgctgga aatcagattg cagtttaaat 4020 ctgagcatat agaaagtccg tttcttctat gtcagcagat gctttttgtg tgaggtttag 4080 gtatactgca ttatttgaca taaaccagtg tttctgccct atgtcttcag aatgacaatt 4140 ctttatgaaa ctaatagaag aacagaagac aattgcaaaa tcatgatgaa gatactaatt 4200 gctttagaat taaggaatac aaaaaataat atgagctgca gttataggat cagaaaagtt 4260 aaaatgggaa tgtattcgag tgtttattat gtgatcagtg ctaagaagtg tcatcattta 4320 attttacact taacggtaat cctgtgagga ttacgctatt attaaatgca tttgatagat 4380 tacaaaaagg cttatggttg gtaaaaattg acccaagtag aagagatcgt gtttttattc 4440 aggttttctg attatagagt ttgagagttt gaccatcatt agtgagtagt gactatattg 4500 tgtctgaatt attgacacaa tttctgatat tcatatgtac caggctgttt cttagagtgg 4560 ggacagaaat gcaagggctg ctagttctga tgtataggag aaactttcat tcattttgca 4620 tttatcattt taaacgttgt atatgtctat ctgggcatgt gttcaagaac acaaggaagt 4680 attaaatcac tccttcttct gaggtttgac tagcaagttg ggctagagtt acaaataaaa 4740 tacaggttcc tagtgaaatc tgaatttcag atacacaacc ataatttatt ggaaatccaa 4800 atttaactgg gaatcttcta ttattctctg ctctagaacg ccacacttct gatatttctc 4860 attgctgtct aagctcttgt gtgtttggtt tttggccatc gctttcactg ctctttaagc 4920 tcccccagag gagtggagag gtctgttttc cctcgtttgg attcctagag gcagcgcagg 4980 cctggcacaa ggtcatcact aaggaagtgt tcacagggtg aacgcggtgg gtgctgttga 5040 aggtaccggt aaagcgtgtg ggatgagagg agcagagagt gtctttgggg ctcccaggag 5100 gaggcggcgc gggctgcggt gctgggcgga tcctcctcca gctcctgctt ggaggtctcc 5160 agaacaggct ggaggcaggg agggggtccc aaaagcctgg ggatgagaag gggttttccc 5220 gcatggtccc ccaggccccc gttcgcctca ggaagacgga ggatgagctc ctgggctgca 5280 ggtggtgggc gttgcgggtg gggccggtta aggttccagc gcccgcaccc cgctcaggga 5340 gccccggatg gtggcgtcgc tgtccgtgtc ttctcaggag gccgccctgt gaccggatgg 5400 ttcgtgtccc cacagcacgt ttcctgtggc agcctaagag ggagtgtcat ttcttcaatg 5460 ggacggagcg ggtgcggttc ctggacagat acttctataa ccaggaggag tccgtgcgct 5520 tcgacagcga cgtgggggag ttccgggcgg tgacggagct ggggcggcct gacgctgagt 5580 actggaacag ccagaaggac atcctggagc aggcgcgggc cgcggtggac acctactgca 5640 gacacaacta cggggttgtg gagagcttca cagtgcagcg gcgaggtgag catggccgcg 5700 ggcggggcct gagtccccgt gagctgggaa tctgagtgtg tgtgtgtgtg tgtgtgtgtg 5760 tgtgtgtgtg tgtgtgagag agagacagag agagacagag agaggaagag agagagagag 5820 cgccatctgt gagcatttag aatcctctca gtccggagca agcagttctg agagcacagg 5880 tgtgtgtgta aagtgtggat ttgtctgtgt ctgtgtgtct gttgtgggag gggaggcagg 5940 agggggctgt ttcttatcct tggagacctc tgtggggagg tgacaaggga ggtgggtgct 6000 gggggctgga gagagaggag accttgatta tctcggtcct tagagatgca gggaagggaa 6060 atgtaaggtg tgtgtggttg gggtgaaggt ttaggggagg actgctgagg ggtaaggcag 6120 gtttgggata atgtgaggag gccagttcca gactctccct ggcatacacc cttcgtgtaa 6180 tctctgaatt aaaagtgtgt gctgtttgtt tgtaaaagca atagattaat ttctagagga 6240 actgagtaga cctctgaggc acctctgaag cttctttaga tctaaatttc ttcctagttt 6300 tttgtttttt tcagtgtgta tatttttaca tagtagaaat gactgtgaaa ctaacttttt 6360 gaattaaagt tttgacacgg ttactatttt attataatgc tggtagtttt ctagtagtta 6420 catattattc ttttatatat aatatttgtg acacaactca cctcactttc ccgtttgttg 6480 acctttatta tgacattcac cagaagttga aattgtgtgt ttctggttaa tttttaattt 6540 atatttttta tttgtaattc ctttgaatta ttttgcccta tttattggcc gattataatt 6600 attgctctaa gaattcccta ttgtatttgg taggtaatgg acaatgatct acggtctaat 6660 atcttgaggg cttagtattt ttctcagtga ctttctgcgt tctttgtact ataagattat 6720 taacacttta ttgatatttg atccagcatt tgctccagtt tgtggtttgt atgtggattt 6780 tgaaaattct tttccatgtt aagaatttga acatttttat ttaataaaat atattgcaac 6840 atttttatta atgatctaca atccatctga aatctgccat tttgtggcat tgttgtctcc 6900 aggtttctcc ttacttctaa aaaaatagtt gtatttattg agagtatgct agtgtcgggg 6960 attttcctgg gcataagcac cccaagtaac gagtcccaga cactgcctta atccaaatgt 7020 gattctggaa agaaaaatca ttttacaatg ataggcctaa taataattat gcttgtgttg 7080 cacgggagat gcattgatca gctaaatgta aatataagaa ctttcaaaac ttaaatgacg 7140 ttccctaatc cttctctctg cttcaggact catgcttttc taggaaagta aaaatttgga 7200 gaatcatttc tgtctgtccc accttcccag gggcagaaca atttctgttg tgttctaagg 7260 tgtgagtgca tgggagtagt attcctaaaa ttcatacttg gtttcctcat gtacccaact 7320 ctgtcccttt atctatgcat attgctttaa atcatatttt tctgtcaagg tgtacaagga 7380 tgataaatag gtgccaagtg gagcactcaa gtgtgatgag tgccctcaca gtggaatgga 7440 gtgagaagct ttctgacctc ataaactgaa ggctatcttc agtcattgtt ttatatattt 7500 tacgtgcatt aatcctcata taaccccaag aggtaaatta gtataattat ccttcattgt 7560 aggtgacaaa gttgagacac agaagaatca aaaaactctt ccaggatcaa ccagtaaaag 7620 gcagaccttg gattcgaacc aggcaacctg gctcaaatat cagttttaat tactacactc 7680 tgtactttcc aagatttgta aacagtttga caatgcatgc cgatttaaaa ctatgaagaa 7740 acaaacacaa tttttcacaa cacctctcaa atctaatggg tcctcactgt caagattaaa 7800 ttccaggctg atgacactgt aaggtcacat ggccagctgt gctataggcc tggtcaaggc 7860 cagagcctgg gtttgcagag aagcagacac acagccaaac caggagactt actctgtctt 7920 cctgactcat tccctctacg ttgtttttct cctagtccaa cctaaggtga ctgtatatcc 7980 ttcaaagacc cagcccctgc agcaccacaa cctcctggtc tgctctgtga gtggtttcta 8040 tccaggcagc attgtagtca ggtggttcct gaacggccag gaagagaagg ctgggatggt 8100 gtccacaggc ctgatccaga atggagactg gaccttccag accctggtga tgctggaaac 8160 agttcctcga agtggagagg tttacacctg ccaagtggag cacccaagcg tgacaagccc 8220 tctcacagtg gaatggagtg agcagctttc tgacttccta aatttctcac ccactaagaa 8280 ggggaccgtg ctaatccctg agtgtcaggt tcctcctctc ccacatccta ttttaatttg 8340 ctccatgttc tcatctccat cagcacaggt cactgggggt agccctgtag gtgtttctag 8400 aaacacctgt acctcctgga gaagcagtct cgcctgccag gcgggagaga ctgtccctct 8460 tttgaacctc cccatgattt tgcaggtcag ggtcacccac tctcccaggc tccaggccct 8520 gcctctgggt ctgagactga gtttctggtg ctgttgctct gagttatttt ttgtgatctg 8580 ggaagaggag aagtgtaggg gcctacctga catgagggga gtccaatctc agccctgctt 8640 tttattagct ttgtcactct agacaaacta cttatcctca ttgagtctca ggctttctgt 8700 ggatcagatg ttgaacttgt gccttacatc aaggctgtaa tatttgaatg agtttgatgt 8760 ctgaacgtcg taactgttca gtgtaatttg aaatcctttt tttctcctga aatggctagt 8820 tattttagtt cttgtgaggc agctttctgc cccattttca aagctctaaa tcttagagtc 8880 tcaagtaaaa aggttcaatt tggaataaac atcactaaac ctggcttcct ctctcaggag 8940 cacggtctga atctgcacag agcaagatgc tgagtggagt cgggggcttt gtgctgggcc 9000 tgctcttcct tggggccggg ctgttcatct acttcaggaa tcagaaaggt gaggagcctt 9060 tgggagctgg ctctctccat aggcttttct ggaggaggaa ctatggcttt gctgaggtta 9120 gttctcagta tatgagtggc cctgaataaa gcctttcttt ccccaaacgg ctctaatgtc 9180 ctgctaatcc agaaatcatc agtgcatggt tactatgtga aagcataata gcttgtggcc 9240 tgcagagacg agaggaaggt taacaagtag gggtcctttg gtttgagatc ctggagcaaa 9300 ttaaggaaga gccactaagg ctaatggaat tacactggat cctgtgacag acacttcagg 9360 cttcatgggt cacatggtct gtttctgctc ctttctgccc tggttggtgt gggttgtggt 9420 gttagagaaa tctcaggtgg gagatctggg gctgggacat tgtgttggag gacagatttg 9480 cttcaataac ttttaagtgt atatcttttc ctctttttcc caggacactc tggacttcag 9540 ccaacaggta atacctttta atcctctttt agaaacagac acagtttccc tagtgagagg 9600 tgaagccagc tggacttctg ggtggggtgg ggacttggag aacttttctt acaagaggtt 9660 tttttttgtt tttttttttt tttttttttt tgagacggag tctcgctctg tcgcccaggc 9720 tggagtgcag tggcgggatc tcggctcact gcaagctccg cctcccgggt tcacgccatt 9780 ctcctgcctc agcctcccaa gtagctggga ctacaggcgc ccgccactac gcccggctaa 9840 ttttttgtat ttttagtaga gacggggttt caccgtttta gccaggatgg tctcgatctc 9900 ctgacctcgt gatccgcccg cctcggcctc ccaaagtgct gggattacag gcgtgagcca 9960 ccgcgcccgg cctacaagag gtttctaaat gcaccaatca gtgctttgta aaaacacacc 10020 aataggttct ctgtggctag ctggatgttt gtaaaatgga ccaattcgca ctctgtaaaa 10080 tagaccaatc agcactcttt aaaatggacc aatcagcact tttaaaatgg gccaatcacc 10140 actctttaaa atggaccaat cagcactctt taaaatggac caatctgcag gacatgggca 10200 gggacaaata caggaataaa agctggccac cccaaccagc agtggcaacc cactcaggtc 10260 ctcttccctg ctgtggaagt tttgttcttt tgatcttcac aataaatctt gctgctgccc 10320 actctttgga tccctgccgc ctttaagagc tgtaacactc actgtgaagg tctgcaggaa 10380 gtcagcgaga ccacaaaccc accggaagga acaaactcag gacacaccag aatgatggta 10440 gaggtgataa ggcatgagac agaaataata ggaaagactt tggatccaaa tttctgatca 10500 ggcaatttac accaaaattc ctcctctcca cttagaaaag gtgtgctctg cgggactatt 10560 ggctcagggg agactcagga acttcttttt cttcttcctg cagtgctctc atctgagccc 10620 ttgaaagagg ggaaaagaaa ctgttagtag agccaggttg aaaacaacac tctcctctgt 10680 cttttgcagg attcctgagc tgaaatgcag atgaccacat tcaaggaaga actttctgcc 10740 ccggctttgc aggatgaaaa gctttcctgc ttggcagtta ttcttccaca agagagggct 10800 ttctcaggac ctggttgcta ctggttcggc aactgcagaa aatgtcctcc cttgtggctt 10860 cctcagctcc tgcccttggc ctgaagtccc agcattgatg gcag 10904 //