Dbfetch
ID KX687263; SV 1; linear; genomic DNA; STD; HUM; 10826 BP. XX AC KX687263; XX DT 18-AUG-2017 (Rel. 133, Created) DT 18-AUG-2017 (Rel. 133, Last updated, Version 1) XX DE Homo sapiens isolate IH18 MHC class II antigen (HLA-DRB1) gene, DE HLA-DRB1*15_02_02e1 allele, partial cds. XX KW . XX OS Homo sapiens (human) OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; OC Homo. XX RN [1] RP 1-10826 RA Barsakis K., Babrzadeh F., Chi A., Mindrinos M.N., Fernandez-Vina M.A.; RT "HLA variation in coding and non-coding gene segments"; RL Unpublished. XX RN [2] RP 1-10826 RA Barsakis K., Babrzadeh F., Chi A., Mindrinos M.N., Fernandez-Vina M.A.; RT ; RL Submitted (07-AUG-2016) to the INSDC. RL Stanford Blood Center, Stanford School of Medicine, 3165 Porter Drive, Palo RL Alto, CA 94304, USA XX DR MD5; b1ba1dde6bff59cc6fe187ae1e15abf2. DR IMGT/HLA; HLA-DRB1*15:02:02; HLA00868. XX FH Key Location/Qualifiers FH FT source 1..10826 FT /organism="Homo sapiens" FT /isolate="IH18" FT /mol_type="genomic DNA" FT /db_xref="taxon:9606" FT gene <173..>9679 FT /gene="HLA-DRB1" FT /allele="HLA-DRB1*15_02_02e1" FT mRNA join(<173..272,5540..5809,8088..8369,9070..9180, FT 9656..>9679) FT /gene="HLA-DRB1" FT /allele="HLA-DRB1*15_02_02e1" FT /product="MHC class II antigen" FT CDS join(173..272,5540..5809,8088..8369,9070..9180,9656..>9679) FT /codon_start=1 FT /gene="HLA-DRB1" FT /allele="HLA-DRB1*15_02_02e1" FT /product="MHC class II antigen" FT /db_xref="GOA:A0A223G1B6" FT /db_xref="InterPro:IPR000353" FT /db_xref="InterPro:IPR003006" FT /db_xref="InterPro:IPR003597" FT /db_xref="InterPro:IPR007110" FT /db_xref="InterPro:IPR011162" FT /db_xref="InterPro:IPR013783" FT /db_xref="InterPro:IPR014745" FT /db_xref="InterPro:IPR036179" FT /db_xref="UniProtKB/TrEMBL:A0A223G1B6" FT /protein_id="AST15777.1" FT /translation="MVCLKLPGGSCMTALTVTLMVLSSPLALSGDTRPRFLWQPKRECH FT FFNGTERVRFLDRYFYNQEESVRFDSDVGEFRAVTELGRPDAEYWNSQKDILEQARAAV FT DTYCRHNYGVGESFTVQRRVQPKVTVYPSKTQPLQHHNLLVCSVSGFYPGSIEVRWFLN FT GQEEKAGMVSTGLIQNGDWTFQTLVMLETVPRSGEVYTCQVEHPSVTSPLTVEWRARSE FT SAQSKMLSGVGGFVLGLLFLGAGLFIYFRNQKGHSGLQPT" XX SQ Sequence 10826 BP; 2829 A; 2167 C; 2626 G; 3204 T; 0 other; gctattgaac tcagatgctg attggttctc caacacgaga ttacccaacc caggagcaag 60 gaaatcagta acttcctccc tataacttgg aatgtgggtg gaggggttca tagttctccc 120 tgagtgagac ttgcctgctt ctctggcccc tggtcctgtc ctgttctcca gcatggtgtg 180 tctgaagctc cctggaggct cctgcatgac agcgctgaca gtgacactga tggtgctgag 240 ctccccactg gctttgtctg gggacacccg acgtaagtgc acattgcggg tgctgagcta 300 ctatggggtg gggaaaatag ggagttttgt taacattgtg cccaggccat gtcccttaag 360 aaattgtgac gttttcttca gagattgccc atctttatca ttggatccca aattatttcc 420 tccataaaag gagcttgggt acttgccctc ttcatgagac ttgtgtaagg ggcctttgca 480 caagtcattt cttttcaaat ctccaccaat aaaacctttg catcacatgt cctcagggtc 540 tttagaggat ttagaaataa ggattctaaa ataaattccc catacagcac ttccctttat 600 tatgttgact tatgtcagac aaaaggaggt tcttactgaa aattttgtgg gagtcaaggg 660 aattcaaagg gtctctccta gacgatccag tgttaggttc cccacaggac ctttggtgtt 720 ggccatagtc ctcatatgtg aggatggacc cagtggcctc cccattatct cctttctttt 780 cttgctgaac tccaatgttt ataaggcctg tatccctgta gtgtatgtag gttctctgac 840 agaagttata cttagtgctc ttcctttctt gtggggaaaa gtccctggaa ctgaagctga 900 gattgttaat acttggagtc accttacaga tacagagcat ttatgaggta ttctttggtg 960 cctaaagaac ttaaggcatc ctctgaaaaa ctagcccagg ttcgtgttca ttatgaatct 1020 tttttaacct ttctgtactt gtttctcttg catctcctat gtgctctaac tagacatgac 1080 agaagagatt taactaatgt ataaattata tgaaattcta ttttttaagt caaaaataat 1140 caactatcag aaatttaata atgttcaaac tatatactct gtgtggggtt accgagatga 1200 tgtgaacatt gttcacgtct catagggctg aaagtcaatg ggcaagtctt gggaactcat 1260 tgtcttactg gggtcttgtc ctaaatttcc taggttcacc catcatgccc tcagctttcc 1320 ttaactagcc atgtctgctt acctcttcct ccagtttcta tttttcccca gctatgttgt 1380 catcatttcc agaaatctct aaagcttgca cagaacctta gcactatgag attcattgaa 1440 agagactttt tttctctttt tgaggtaggg cctggctctg tcacccagtc tatagctcag 1500 tggtgtgatc gaggctcact gcaacctctg ccacccatgc tcaagtgatc ctccctcctc 1560 aggctccaga gtagctggga atacaggcag gcaaccacgc ccagctaatt tttgtaattt 1620 tggtagacat gagattttgc catgttgccc aggctggtct tgaactgctg gactcaagca 1680 atcctcctgc cttggcctcc caacatgcta ggattataga tgtgagccac tgtgcccagg 1740 caaaagagat gactcttaat aaaaaaattt cctttttctt aaatcactgt ttctttatct 1800 gtgaattctt cttccaacta gaaggaggag aaaaaagaag tttgcctgta tttatcactg 1860 ggaggagaag gggtctagtg tgacattaaa atgaaagagt gctggagctt gagccccttc 1920 ttgctttcca ggatccctac agtgatcagt tcccataccc tggtttattc atgtaaacca 1980 cacttatttt tctcagcagc tactctttac tgggctccat tctaggttca aatcattcta 2040 tttgattaag ttagagagcg tccctactct catggaagtt acacaagagt agaggagaca 2100 gacactaacc caataagcat ttaacaaaga agataatgtt agagagtcat agtgcactga 2160 agaaaagaca tcaggtttgt gaaaaagaga gacatggatt cacctacttt agttcatatg 2220 ttagggagct ccacctgaga aagtgacatt cagctgagac aacaaaataa gtagacagtc 2280 gtgaagatct aagggatgaa agttccaggg agaccgaatc gggggaaagc cctgatgtgt 2340 taaattatgt ggagggagag aaagaaagct agaggggctg atgtatagaa agcaaggaaa 2400 tggagaggca gaagatgagg gtaggacaca gagaggaatt caggagcctc atcattatag 2460 gctctgatgt ccacagtaaa aaaaaattaa attttattat ttatttattt gtttgtttat 2520 tttattttat tttgtgatgg agtctctctc tgttgcccag gctagattgc tgtggcacaa 2580 tctcggctca ctgcaacctc cgcctcctgg gttcaagcga ttctcctgcc tcagcctccc 2640 gattagctgg ggccacaggc gcatgccacc acacctggct aattttttgt atttttagta 2700 gggatagggt ttcaccgtgt tagccaggat ggtctcgatc tcctgacctc gtgatccgcc 2760 cgccttggcc tcccaaagtg ctgggattac aggcgtgagc cactgcgccc ggcctatatt 2820 caatgtttaa aactaattct agctactctg tggggattgg attgttgggg ttcactagtg 2880 gttaggaaga ctatttagga gcacagcagg gaattcttca gggaaaacag gtttgtggct 2940 tcatggagtg cattagtgat aaagatggtg aaaaagataa agtggacaga cttggcatgt 3000 atttttgctt agcttgttaa tgaattactg taaagggggt agaacaatca agcttattcc 3060 taaggatttt cttttgacaa ataaatgggt ggtagtgttg tttattgaga taggaaaaac 3120 tatgggagga aatgatttga agtgggtggt ttgaaataaa agttttgttt aaatatgaga 3180 tgattgattg acatttatgt ggagaaatcc gaaggtcaat ggcatttaag agactcatgg 3240 tgaggccagg gcttcaggta tttatgttgg cagcagcaat acgtgtagtg tgttaaattc 3300 cagggcgtgg aagaggatac atagggagat ggattgtgtg aagaaaaaag aacagggcac 3360 aggccagcaa agggggctga gaaagagccc aaggatgctg gagaaaaacc aagagaacat 3420 catgtgtgta agtccaggaa aatagattat tttcaaggag aagggagagg ccaattgtgg 3480 tgagtaccac taagaggagg ggcaagtgag aatatgatag agaagcaagt gctgggtttg 3540 gtggagtcga tatttgcagt caatggagca tccaggtagg aaactggatt ggaccatttg 3600 aagagtgagt aaaagtgagg acgaggttaa ggttgactgt tttgagtaga gagcttcagg 3660 gaaggattgt tctctgggtt cagggagcca gctgaaccta aaggaaaagg ctaaagaagc 3720 tgaagagaag gaggaggacc tgtgaaccag agatgctcag tcattattag cgaggaaata 3780 cggagagccc ctgtgtgcag tggtgactac tcatgcaaaa tgtcacacag ccaatattta 3840 acacagccag tatttcacac agccaatatt tattagtgac atagcatata ccagttatta 3900 ctctaggtca tgagaatgga gtgataaata aaatgaatcc agtcgccatc actatatgcc 3960 atgtaacatt ttgcaatgac tgtgtatcag gcctatgaat ttcagtattc aatttcaata 4020 atgatcctgt tgtatctgtg gtatttaaaa acatatacat ctctggaatc taaaattgag 4080 aggttataag taacacccag tattacaaat ttagtgctgg aaatcagatt gcagtttaaa 4140 tctgagcata tagaaagtcc gtttcttcta tgtcagcaga tgctttttgt gtgaggttta 4200 ggtatactgc attatttgac ataaaccagt gtttctgccc tatgtcttca gaatgacaat 4260 tctttatgaa actaatagaa gaacagaaga caattgcaaa atcatgatga agatactaat 4320 tgctttagaa ttaaggaata caaaaaataa tatgagctgc agttatagga tcagaaaagt 4380 taaaatggga atgtattcga gtgtttatta tgtgatcagt gctaagaagt gtcatcattt 4440 aattttacac ttaacggtaa tcctgtgagg attacgctat tattaaatgc atttgataga 4500 ttacaaaaag gcttatggtt ggtaaaaatt gacccaagta gaagagatcg tgtttttatt 4560 caggttttct gattatagag tttgagagtt tgaccatcat tagtgagtag tgactatatt 4620 gtgtctgaat tattgacaca atttctgata ttcatatgta ccaggctgtt tcttagagtg 4680 gggacagaaa tgcaagggct gctagttctg atgtatagga gaaactttca ttcattttgc 4740 atttatcatt ttaaacgttg tatatgtcta tctgggcatg tgttcaagaa cacaaggaag 4800 tattaaatca ctccttcttc tgaggtttga ctagcaagtt gggctagagt tacaaataaa 4860 atacaggttc ctagtgaaat ctgaatttca gatacacaac cataatttat tggaaatcca 4920 aatttaactg ggaatcttct attattctct gctctagaac gccacacttc tgatatttct 4980 cattgctgtc taagctcttg tgtgtttggt ttttggccat cgctttcact gctctttaag 5040 ctcccccaga ggagtggaga ggtctgtttt ccctcgtttg gattcctaga ggcagcgcag 5100 gcctggcaca aggtcatcac taaggaagtg ttcacagggt gaacgcggtg ggtgctgttg 5160 aaggtaccgg taaagcgtgt gggatgagag aaggagcaga gagtgtcttt ggggctccca 5220 ggaggaggcg gcgcgggctg cggtgctggg cggatcctcc tccagctcct gcttggaggt 5280 ctccagaaca ggctggaggc agggaggggg tcccaaaagc ctggggatga gaaggggttt 5340 tcccgcatgg tcccccaggc ccccgttcgc ctcaggaaga cggaggatga gctcctgggc 5400 tgcaggtggt gggcgttgcg ggtggggccg gttaaggttc cagcgcccgc accccgctca 5460 gggagccccg gatggtggcg tcgctgtccg tgtcttctca ggaggccgcc ctgtgaccgg 5520 atggttcgtg tccccacagc acgtttcctg tggcagccta agagggagtg tcatttcttc 5580 aatgggacgg agcgggtgcg gttcctggac agatacttct ataaccagga ggagtccgtg 5640 cgcttcgaca gcgacgtggg ggagttccgg gcggtgacgg agctggggcg gcctgatgcc 5700 gagtactgga acagccagaa ggacatcctg gagcaggcgc gggccgcggt ggacacctac 5760 tgcagacaca actacggggt tggtgagagc ttcacagtgc agcggcgagg tgagcatggc 5820 cgcgggcggg gcctgagtcc ccgtgagctg ggaatctgag tgtgtgtgtg tgtgtgtgtg 5880 tgtgtgtgtg tgtgtgtgtg tgtgtgtgtg tgtgagagag agagagagag agagagagag 5940 agagagagag agcgccatct gtgagcattt agaatcctct cagtccggag caagcagttc 6000 tgagagcaca ggtgtgtgtg taaagtgtgg atttgtctgt gtctgtgtgt ctgttgtggg 6060 aggggaggca ggagggggct gtttcttatc cttggagacc tctgtgggga ggtgacaagg 6120 gaggtgggtg ctgggggctg gagagagagg agaccttgat tatctcggtc cttagagatg 6180 cagggaaggg aaatgtaagg tgtgtgtggt tggggtgaag gtttagggga ggactgctga 6240 ggggtaaggc aggtttggga taatgtgagg aggccagttc cagactctcc ctggcataca 6300 cccttcgtgt aatctctgaa ttaaaagtgt gtgctgtttg tttgtaaaag caatagatta 6360 atttctagag gaactgagta gacctctgag gcacctctga agcttcttta gatctaaatt 6420 tcttcctagt tttttgtttt tttcagtgtg tatattttta catagtagaa atgactgtga 6480 aactaacttt ttgaattaaa gttttgacac ggttactatt ttattataat gctggtagtt 6540 ttctagtagt tacatattat tcttttatat ataatatttg tgacacaact cacctcactt 6600 tcccgtttgt tgacctttat tatgacattc accagaagtt gaaattgtgt gtttctggtt 6660 aatttttaat ttatattttt tatttgtaat tcctttgaat tattttgccc tatttattgg 6720 ccgattataa ttattgctct aagaattccc tattgtattt ggtaggtaat ggacaatgat 6780 ctacggtcta atatcttgag ggcttagtat ttttctcagt gactttctgc gttctttgta 6840 ctataagatt attaacactt tattgatatt tgatccagca tttgctccag tttgtggttt 6900 gtatgtggat tttgaaaatt cttttccatg ttaagaattt gaacattttt atttaataaa 6960 atatattgca acatttttat taatgatcta caatccatct gaaatctgcc attttgtggc 7020 attgttgtct ccaggtttct ccttacttct aaaaaaatag ttgtatttat tgagagtatg 7080 ctagtgtcgg ggattttcct gggcataagc accccaagta acgagtccca gacactgcct 7140 taatccaaat gtgattctgg aaagaaaaat cattttacaa tgataggcct aataataatt 7200 atgcttgtgt tgcacgggag atgcattgat cagctaaatg taaatataag aactttcaaa 7260 acttaaatga cgttccctaa tccttctctc tgcttcagga ctcatgcttt tctaggaaag 7320 taaaaatttg gagaatcatt tctgtctgtc ccaccttccc aggggcagaa caatttctgt 7380 tgtgttctaa ggtgtgagtg catgggagta gtattcctaa aattcatact tggtttcctc 7440 atgtacccaa ctctgtccct ttatctatgc atattgcttt aaatcatatt tttctgtcaa 7500 ggtgtacaag gatgataaat aggtgccaag tggagcactc aagtgtgatg agtgccctca 7560 cagtggaatg gagtgagaag ctttctgacc tcataaactg aaggctatct tcagtcattg 7620 ttttatatat tttacgtgca ttaatcctca tataacccca agaggtaaat tagtataatt 7680 atccttcatt gtaggtgaca aagttgagac acagaagaat caaaaaactc ttccaggatc 7740 aaccagtaaa aggcagacct tggattcgaa ccaggcaacc tggctcaaat atcagtttta 7800 attactacac tctgtacttt ccaagatttg taaacagttt gacaatgcat gccgatttaa 7860 aactatgaag aaacaaacac aatttttcac aacacctctc aaatctaatg ggtcctcact 7920 gtcaagatta aattccaggc tgatgacact gtaaggtcac atggccagct gtgctatagg 7980 cctggtcaag gccagagcct gggtttgcag agaagcagac acacagccaa accaggagac 8040 ttactctgtc ttcctgactc attccctcta cgttgttttt ctcctagtcc aacctaaggt 8100 gactgtatat ccttcaaaga cccagcccct gcagcaccac aacctcctgg tctgctctgt 8160 gagtggtttc tatccaggca gcattgaagt caggtggttc ctgaacggcc aggaagagaa 8220 ggctgggatg gtgtccacag gcctgatcca gaatggagac tggaccttcc agaccctggt 8280 gatgctggaa acagttcctc gaagtggaga ggtttacacc tgccaagtgg agcacccaag 8340 cgtgacaagc cctctcacag tggaatggag tgagcagctt tctgacttcc taaatttctc 8400 acccactaag aaagggaccg tgctaatccc tgagtgtcag gttcctcctc tcccacatcc 8460 tattttaatt tgctccatgt tctcatctcc atcagcacag gtcactgggg gtagccctgt 8520 aggtgtttct agaaacacct gtacctcctg gagaagcagt ctcgcctgcc aggcgggaga 8580 gactgtccct cttttgaacc tccccatgat tttgcaggtc agggtcaccc actctcccag 8640 gctccaggcc ctgcctctgg gtctgagact gagtttctgg tgctgttgct ctgagttatt 8700 ttttgtgatc tgggaagagg agaagtgtag gggcctacct gacatgaggg gagtccaatc 8760 tcagccctgc ttttcattag ctttgtcact ctagacaaac tacttatcct cattgagtct 8820 caggctttct gtggatcaga tgttgaactt gtgccttaca tcaaggctgt aatatttgaa 8880 tgagtttgat gtctgaacgt cgtaactgtt cagtgtaatt tgaaatcctt tttttctcct 8940 gaaatggcta gttattttag ttcttgtgag gcagctttct gccccatttt caaagctcta 9000 aatcttagag tctcaagtaa aaaggttcaa tttggaataa acatcactaa acctggcttc 9060 ctctctcagg agcacggtct gaatctgcac agagcaagat gctgagtgga gtcgggggct 9120 ttgtgctggg cctgctcttc cttggggccg ggctgttcat ctacttcagg aatcagaaag 9180 gtgaggagcc tttgggagct ggctctctcc ataggctttt ctggaggagg aactatggct 9240 ttgctgaggt tagttctcag tatatgagtg gccctgaata aagcctttct ttccccaaac 9300 ggctctaatg tcctgctaat ccagaaatca tcagtgcatg gttactatgt gaaagcataa 9360 tagcttgtgg cctgcagaga cgagaggaag gttaacaagt aggggtcctt tggtttgaga 9420 tcctggagca aattaaggaa gagccactaa ggctaatgga attacactgg atcctgtgac 9480 agacacttca ggcttcatgg gtcacatggt ctgtttctgc tcctttctgc cctggttggt 9540 gtgggttgtg gtgttagaga aatctcaggt gggagatctg gggctgggac attgtgttgg 9600 aggacagatt tgcttcaata acttttaagt gtatatcttt tcctcttttt cccaggacac 9660 tctggacttc agccaacagg taataccttt taatcctctt ttagaaacag acacagtttc 9720 cctagtgaga ggtgaagcca gctggacttc tgggtggggt ggggacttgg agaacttttc 9780 ttacaagagg tttttttttt tttttttttt tttttttttt ttttttcttt gagacggagt 9840 ctcgctctgt cgcccaggct ggagtgcagt ggcgggatct cggctcactg caagctccgc 9900 ctcccgggtt cacgccattc tcctgcctca gcctcccaag tagctgggac tacaggcgcc 9960 cgccactacg cccggctaat tttttgtatt tttagtagag acggggtttc accgttttag 10020 ccaggatggt ctcgatctcc tgacctcgtg atccgcccgc ctcggcctcc caaagtgctg 10080 ggattacagg cgtgagccac cgcgcccggc ctacaagagg tttctaaatg caccaatcag 10140 tgctttgtaa aaacacacca ataggttctc tgtggctagc tggatgtttg taaaatggac 10200 caattcgcac tctgtaaaat agaccaatca gcactcttta aaatggacca atcagcactt 10260 ttaaaatggg ccaatcacca ctctttaaaa tggaccaatc agcactcttt aaaatggacc 10320 aatctgcagg acatgggcag ggacaaatac aggaataaaa gctggccacc ccaaccagca 10380 gtggcaaccc actcaggtcc tcttccctgc tgtggaagtt ttgttctttt gatcttcaca 10440 ataaatcttg ctgctgccca ctctttggat ccctgccgcc tttaagagct gtaacactca 10500 ctgtgaaggt ctgcaggaag tcagcgagac cacaaaccca ccggaaggaa caaactcagg 10560 acacaccaga atgatggtag aggtgataag gcatgagaca gaaataatag gaaagacttt 10620 ggatccaaat ttctgatcag gcaatttaca ccaaaattcc tcctctccac ttagaaaagg 10680 tgtgctctgc gggactattg gctcagggga gactcaggaa cttctttttc ttcttcctgc 10740 agtgctctca tctgagccct tgaaagaggg gaaaagaaac tgttagtaga gccaggttga 10800 aaacaacact ctcctctgtc ttttgc 10826 //