Dbfetch
ID GU376469; SV 1; linear; genomic DNA; STD; HUM; 4336 BP. XX AC GU376469; XX DT 23-FEB-2010 (Rel. 103, Created) DT 12-DEC-2012 (Rel. 115, Last updated, Version 2) XX DE Homo sapiens MHC class I antigen (HLA-Cw) gene, HLA-Cw*0130 allele, DE promoter region and complete cds. XX KW . XX OS Homo sapiens (human) OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; OC Homo. XX RN [1] RP 1-4336 RX DOI; 10.1016/j.humimm.2010.03.001. RX PUBMED; 20226825. RA Deng Z., Wang D., Xu Y., Gao S., Zhou H., Yu Q., Yang B.; RT "HLA-C polymorphisms and PCR dropout in exons 2 and 3 of the Cw*0706 allele RT in sequence-based typing for unrelated Chinese marrow donors"; RL Hum. Immunol. 71(6):577-581(2010). XX RN [2] RP 1-4336 RA Xu Y.P., Deng Z.H., Yang B.C.; RT ; RL Submitted (02-JAN-2010) to the INSDC. RL Immunogenetic Laboratory, Shenzhen Blood Center, 2 Meigang West Street, RL Nigang West Road, Shenzhen, Guangdong 518035, China XX DR MD5; 6175b9317288125a1aa7c44efac60a73. DR IMGT/HLA; HLA-C*01:30; HLA04020. XX FH Key Location/Qualifiers FH FT source 1..4336 FT /organism="Homo sapiens" FT /chromosome="6" FT /map="6p21.3" FT /mol_type="genomic DNA" FT /PCR_primers="fwd_seq: tggactcacacarggaaactc, rev_seq: FT gggacaaggacaatggagcag" FT /db_xref="taxon:9606" FT gene <1..4336 FT /gene="HLA-Cw" FT /allele="HLA-Cw*0130" FT regulatory <1..6 FT /gene="HLA-Cw" FT /allele="HLA-Cw*0130" FT /regulatory_class="promoter" FT mRNA join(7..932,1063..1332,1579..1854,2442..2717,2839..2958, FT 3398..3430,3538..3585,3750..4336) FT /gene="HLA-Cw" FT /allele="HLA-Cw*0130" FT /product="MHC class I antigen" FT 5'UTR 7..859 FT /gene="HLA-Cw" FT /allele="HLA-Cw*0130" FT CDS join(860..932,1063..1332,1579..1854,2442..2717,2839..2958, FT 3398..3430,3538..3585,3750..3754) FT /codon_start=1 FT /gene="HLA-Cw" FT /allele="HLA-Cw*0130" FT /product="MHC class I antigen" FT /note="glycoprotein" FT /db_xref="GOA:D3XQC2" FT /db_xref="InterPro:IPR001039" FT /db_xref="InterPro:IPR003006" FT /db_xref="InterPro:IPR003597" FT /db_xref="InterPro:IPR007110" FT /db_xref="InterPro:IPR010579" FT /db_xref="InterPro:IPR011161" FT /db_xref="InterPro:IPR011162" FT /db_xref="InterPro:IPR013783" FT /db_xref="InterPro:IPR036179" FT /db_xref="InterPro:IPR037055" FT /db_xref="UniProtKB/TrEMBL:D3XQC2" FT /protein_id="ADC79685.1" FT /translation="MRVMAPRTLILLLSGALALTETWACSHSMKYFFTSVSRPGRGEPR FT FISVGYVDDTQFVRFDSDAASPRGEPRAPWVEQEGPEYWDRETQKYKRQAQTDRVSLRN FT LRGYYNQSEAGSHTLQWMCGCDLGPDGRLLRGYDQYAYDGKDYIALNEDLRSWTAADTA FT AQITQRKWEAAREAEQRRAYLEGTCVEWLRRHLENGKETLQRAEHPKTHVTHHPVSDHE FT ATLRCWALGFYPAEITLTWQWDGEDQTQDTELVETRPAGDGTFQKWAAVMVPSGEEQRY FT TCHVQHEGLPEPLTLRWEPSSQPTIPIVGIVAGLAVLAVLAVLGAVVAVVMCRRKSSGG FT KGGSCSQAASSNSAQGSDESLIACKA" FT 3'UTR 3755..4336 FT /gene="HLA-Cw" FT /allele="HLA-Cw*0130" XX SQ Sequence 4336 BP; 878 A; 1187 C; 1301 G; 970 T; 0 other; gggctagaga atgaggataa ttttaaatgc aacaacccag agtcacagat ccatagtctg 60 cgaaagtaaa acaggaggtt tgagaattta attgtaatgc agttttgaca caggtctttc 120 acagattgga attctaatca ttcagggatt accaatattg tgctacctac tgtatcaata 180 aacaaaaagg aaactggtct ctatgagaat ctctacctgg tgctttcaga caacacttca 240 ccaggtttaa agagaaaact cctgactcta cacgtccatt cccagggcga gctcactgtc 300 tggcatcaag ttccccatgg tgagtttccc tgtacaagag tccaagggga gaggtaagtg 360 tcctttattt tgctggatgt agtttaatat tacctgaggt aaggtaaggc aaagagtggg 420 aggcagggag tccagttcag ggacggggat tccaggagaa gtgaagggga aggggctggg 480 cgcagcctgg gggtctctcc ctggtttcca cagacagatc cttggccagg actcaggcac 540 acagtgtgac aaagatgctt ggtgtaggag aagagggatc aggacgaagt cccaggtccc 600 gggcggggtt ctcagggtct caggctccaa gggccgtgtc tgcactgggg aggcgccgcg 660 ttgaggattc tccactcccc tgagtttcac ttcttctccc aacctgcgtc gggtccttct 720 tcctgaatac tcatgacgcg tccccaattc ccactcccat tgggtgtcgg gttctagaga 780 agccaatcag cgtctccgca gtcccggttc taaagtcccc agtcacccac ccggactcag 840 attctcccca gacgccgaga tgcgggtcat ggcgccccga accctcatcc tgctgctctc 900 gggagccctg gccctgaccg agacctgggc ctgtgagtgc ggggttggga gggaaacggc 960 ctctgcggag aggaacgagg tgcccgcccg gcgagggcgc aggacccggg gagccgcgca 1020 gggaggaggg tcgggcgggt ctcagcccct cctcgccccc aggctcccac tccatgaagt 1080 atttcttcac atccgtgtcc cggcctggcc gcggagagcc ccgcttcatc tcagtgggct 1140 acgtggacga cacgcagttc gtgcggttcg acagcgacgc cgcgagtccg agaggggagc 1200 cgcgggcgcc gtgggtggag caggaggggc cggagtattg ggaccgggag acacagaagt 1260 acaagcgcca ggcacagact gaccgagtga gcctgcggaa cctgcgcggc tactacaacc 1320 agagcgaggc cggtgagtga ccccggcccg gggcgcaggt cacgacccct cctcatcccc 1380 cacggacggc ccgggtcgcc ccaagtctcc cggtctgaga tccaccccga ggctgcggaa 1440 cccgcccaga ccctcgaccg gagagagccc cagtcacctt tacccggttt cattttcagt 1500 ttaggccaaa atccccgcgg gttggtcggg actggggcgg ggctcggggg acggggctga 1560 ccacgggggc ggggccaggg tctcacaccc tccagtggat gtgtggctgc gacctggggc 1620 ccgacgggcg cctcctccgc gggtatgacc agtacgccta cgacggcaag gattacatcg 1680 ccctgaacga ggacctgcgc tcctggaccg ccgcggacac cgcggctcag atcacccagc 1740 gcaagtggga ggcggcccgt gaggcggagc agcggagagc ctacctggag ggcacgtgcg 1800 tggagtggct ccgcagacac ctggagaacg ggaaggagac gctgcagcgc gcgggtacca 1860 ggggcagtgg ggagccttcc ccatctcccg tagatctccc ggcatggcct cccacgagga 1920 ggggaggaaa atgggatcag cgctagaata tcgccctccc ttgaatggag aatgggatga 1980 gttttcctga gtttcctctg agggccccct ctgctctcta ggacaattaa gggatgaagt 2040 ccttgaggaa atggagggga agacagtccc tggaatactg atcaggggtc ccctttgacc 2100 actttgacca ctgcagcagc tgtggtcagg ctgctgacct ttctctcagg ccttgttctc 2160 tgcctcacgc tcaatgtgtt tgaaggtttg attccagctt ttctgagtcc ttcggcctcc 2220 actcaggtca ggaccagaag tcgctgttcc tccctcagag actagaactt tccaatgaat 2280 aggagattat cccaggtgcc tgtgtccagg ctggcgtctg ggttctgtgc ccccttcccc 2340 accccaggtg tcctgtccat tctcaggatg gtcacatggg cgctgttgga gtgtcgcaag 2400 agagatacaa agtgtctgaa ttttctgact cttcccgtca gaacacccaa agacacacgt 2460 gacccaccat cccgtctctg accatgaggc caccctgagg tgctgggccc tgggcttcta 2520 ccctgcggag atcacactga cctggcagtg ggatggggag gaccaaactc aggacaccga 2580 gcttgtggag accaggccag caggagatgg aaccttccag aagtgggcag ctgtgatggt 2640 gccttctgga gaagagcaga gatacacgtg ccatgtgcag cacgaggggc tgccggagcc 2700 cctcaccctg agatggggta aggaggggga tgaggggtga tgtgtcttct cagggaaagc 2760 agaagtcctg gagcccttca gccgggtcag ggctgaggct tggaggtcag ggcccctcac 2820 cttcccctcc tttcccagag ccgtcttccc agcccaccat ccccatcgtg ggcatcgttg 2880 ctggcctggc tgtcctggct gtcctagctg tcctaggagc tgtggtggct gttgtgatgt 2940 gtaggaggaa gagctcaggt agggaagggg tgaggagtgg ggtctgggtt ttcttgttcc 3000 actgggagtt tcaagcccca ggtagaagtg tgccccacct cgttactgga agcaccatcc 3060 acacatgggc catcccagcc tgggaccctg tgtgccagca cttactctgt tgtgaagcac 3120 atgacaatga aggacagatg tatcaccttg atgattatgg tgttggggtc cttgattcca 3180 gcattcatga gtcaggggaa ggtccctgct aaggacagac cttaggaggg cagttgcttc 3240 agaacccaca gctgctttcc ccgtgtttcc tgatcctgcc ctgggtctgc agtcatagtt 3300 ctggaaactt ctcttgggtc caagactagg aggttcccct aagatcgcat ggccctgcct 3360 cctccctgtc ccctcacagg gcattttctt cccacaggtg gaaaaggagg gagctgctct 3420 caggctgcgt gtaagtgatg gcggtgggcg tgtggaggag ctcacccacc ccataattcc 3480 tcttgtccca catctcctgc gggctctgac caggtctttt tttttgttct accccagcca 3540 gcaacagtgc ccagggctct gatgagtctc tcatcgcttg taaaggtgag attctgggga 3600 gctgaagtgg tcgggggtgg ggcagaggga aaaggcctag gtaatgggga tcctttgatt 3660 gggacgtttc gaatgtgtgg tgagctgttc agagtgtcat cacttaccat gactgacctg 3720 aatttgttca tgactattgt gttctgtagc ctgagacagc tgcctgtgtg ggactgagat 3780 gcaggatttc ttcacacctc tcctttgtga cttcaagagc ctctggcatc tctttctgca 3840 aaggcatctg aatgtgtctg cgttcctgtt agcataatgt gaggaggtgg agagacagcc 3900 cacccccgtg tccaccgtga cccctgtccc cacactgacc tgtgttccct ccccgatcat 3960 ctttcctgtt ccagagaagt gggctggatg tctccatctc tgtctcaact tcatggtgcg 4020 ctgagctgca acttcttact tccctaatga agttaagaac ctgaatataa atttgttttc 4080 tcaaatattt gctatgaagg gttgatggat taattaaata agtcaattcc tggaagttga 4140 gagagcaaat aaagacctga gaaccttcca gaatccgcat gttcgctgtg ctgagtctgt 4200 tgcaggtggg ggtggggaag gctgtgagga gacgagtgtg gacggggcct gtgcctagtt 4260 gctgttcagt tcttcatggg ctttatgtgg tcagtcctca gctgggtcac cttcactgct 4320 ccattgtcct tgtccc 4336 //