Dbfetch
ID AM087469; SV 1; linear; genomic DNA; STD; HUM; 3095 BP. XX AC AM087469; XX DT 26-OCT-2005 (Rel. 85, Created) DT 17-JUN-2008 (Rel. 96, Last updated, Version 4) XX DE Homo sapiens HLA-A gene for MHC class I antigen, allele HLA-A*0321 XX KW HLA-A gene; HLA-A*0321 allele; human leucocyte antigen A; KW major histocompatibility complex; MHC class I antigen. XX OS Homo sapiens (human) OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; OC Homo. XX RN [1] RP 1-3095 RA Cox S.T.; RT ; RL Submitted (26-SEP-2005) to the INSDC. RL Cox S.T., HLA Research Group, Anthony Nolan Research, The Royal Free RL Hospital, Pond Street, Hampstead, London, NW3 2QG, UNITED KINGDOM. XX RN [2] RA Cox S.T.; RT "A*03XXN has an insertion in exon causing non-expression"; RL Unpublished. XX DR MD5; 665152840dba04b1bdbfefaf3d4913ac. DR IMGT/HLA; HLA-A*03:21N; HLA02369. XX FH Key Location/Qualifiers FH FT source 1..3095 FT /organism="Homo sapiens" FT /chromosome="6" FT /map="6p21.3" FT /mol_type="genomic DNA" FT /db_xref="taxon:9606" FT mRNA join(1..73,204..473,715..990,1569..1845,1948..2064, FT 2507..2539,2722..2729,2857..2861) FT /gene="HLA-A" FT /allele="HLA-A*0321" FT CDS join(1..73,204..473,715..990,1569..1609) FT /gene="HLA-A" FT /allele="HLA-A*0321" FT /product="MHC class I antigen" FT /note="premature stop TGA; this allele is not detected FT serologically" FT /db_xref="InterPro:IPR001039" FT /db_xref="InterPro:IPR011161" FT /db_xref="InterPro:IPR011162" FT /db_xref="InterPro:IPR037055" FT /db_xref="UniProtKB/TrEMBL:Q3BK35" FT /protein_id="CAJ32464.1" FT /translation="MAVMAPRTLLLLLSGALALTQTWAGSHSMRYFFTSVSRPGRGEPR FT FIAVGYVDDTQFVRFDSDAASQRMEPRAPWIEQEGPEYWDQETRNVKAQSQTDRVDLGT FT LRGYYNQSEAGSHTIQIMYGCDVGSDGRFLRGYRQDAYDGKDYIALNEDLRSWTAADMA FT AQITKRKWEAAHEAEQLRAYLDGTCVEWLRRYLENGKETLQRTDPPQDTYDPPPHL" FT exon 1..73 FT /gene="HLA-A" FT /allele="HLA-A*0321" FT /number=1 FT intron 74..203 FT /gene="HLA-A" FT /allele="HLA-A*0321" FT /number=1 FT exon 204..473 FT /gene="HLA-A" FT /allele="HLA-A*0321" FT /number=2 FT intron 474..714 FT /gene="HLA-A" FT /allele="HLA-A*0321" FT /number=2 FT exon 715..990 FT /gene="HLA-A" FT /allele="HLA-A*0321" FT /number=3 FT intron 991..1568 FT /gene="HLA-A" FT /allele="HLA-A*0321" FT /number=3 FT exon 1569..1845 FT /gene="HLA-A" FT /allele="HLA-A*0321" FT /number=4 FT intron 1846..1947 FT /gene="HLA-A" FT /allele="HLA-A*0321" FT /number=4 FT exon 1948..2064 FT /gene="HLA-A" FT /allele="HLA-A*0321" FT /number=5 FT intron 2065..2506 FT /gene="HLA-A" FT /allele="HLA-A*0321" FT /number=5 FT exon 2507..2539 FT /gene="HLA-A" FT /allele="HLA-A*0321" FT /number=6 FT intron 2540..2721 FT /gene="HLA-A" FT /allele="HLA-A*0321" FT /number=6 FT exon 2722..2729 FT /gene="HLA-A" FT /allele="HLA-A*0321" FT /number=7 FT intron 2730..2856 FT /gene="HLA-A" FT /allele="HLA-A*0321" FT /number=7 FT exon 2857..2861 FT /gene="HLA-A" FT /allele="HLA-A*0321" FT /number=8 XX SQ Sequence 3095 BP; 592 A; 883 C; 962 G; 658 T; 0 other; atggccgtca tggcgccccg aaccctcctc ctgctactct cgggggccct ggccctgacc 60 cagacctggg cgggtgagtg cggggtcggg agggaaaccg cctctgcggg gagaagcaag 120 gggccctcct ggcgggggcg caggaccggg ggagccgcgc cgggacgagg gtcgggcagg 180 tctcagccac tgctcgcccc caggctccca ctccatgagg tatttcttca catccgtgtc 240 ccggcccggc cgcggggagc cccgcttcat cgccgtgggc tacgtggacg acacgcagtt 300 cgtgcggttc gacagcgacg ccgcgagcca gaggatggag ccgcgggcgc cgtggataga 360 gcaggagggg ccggagtatt gggaccagga gacacggaat gtgaaggccc agtcacagac 420 tgaccgagtg gacctgggga ccctgcgcgg ctactacaac cagagcgagg ccggtgagtg 480 accccggccg ggggcgcagg tcaggacccc tcatccccca cggacgggcc aggtcgccca 540 cagtctccgg gtccgagatc caccccgaag ccgcgggacc ccgagaccct tgccccggga 600 gaggcccagg cgcctttacc cggtttcatt ttcagtttag gccaaaaatc cccccgggtt 660 ggtcggggct gggcggggct cgggggactg ggctgaccgc ggggtcgggg ccaggttctc 720 acaccatcca gataatgtat ggctgcgacg tggggtcgga cgggcgcttc ctccgcgggt 780 accggcagga cgcctacgac ggcaaggatt acatcgccct gaacgaggac ctgcgctctt 840 ggaccgcggc ggacatggcg gctcagatca ccaagcgcaa gtgggaggcg gcccatgagg 900 cggagcagtt gagagcctac ctggatggca cgtgcgtgga gtggctccgc agatacctgg 960 agaacgggaa ggagacgctg cagcgcacgg gtaccagggg ccacggggcg cctccctgat 1020 cgcctgtaga tctcccgggc tggcctccca caaggagggg agacaattgg gaccaacact 1080 agaatatcac cctccctctg gtcctgaggg agaggaatcc tcctgggttc cagatcctgt 1140 accagagagt gactctgagg ttccgccctg ctctctgaca caattaaggg ataaaatctc 1200 tgaaggagtg acgggaagac gatccctcga atactgatga gtggttccct ttgacaccgg 1260 cagcagcctt gggcccgtga cttttcctct caggccttgt tctctgcttc acactcaatg 1320 tgtgtggggg tctgagtcca gcacttctga gtccctcagc ctccactcag gtcaggacca 1380 gaagtcgctg ttcccttctc agggaataga agattatccc aggtgcctgt gtccaggctg 1440 gtgtctgggt tctgtgctct cttccccatc ccgggtgtcc tgtccattct caagatggcc 1500 acatgcgtgc tggtggagtg tcccatgaca gatgcaaaat gcctgaattt tctgactctt 1560 cccgtcagac cccccccaag acacatatga cccaccaccc catctctgac catgaggcca 1620 ccctgaggtg ctgggccctg ggcttctacc ctgcggagat cacactgacc tggcagcggg 1680 atggggagga ccagacccag gacacggagc tcgtggagac caggcctgca ggggatggaa 1740 ccttccagaa gtgggcggct gtggtggtgc cttctggaga ggagcagaga tacacctgcc 1800 atgtgcagca tgagggtctg cccaagcccc tcaccctgag atggggtaag gagggagatg 1860 ggggtgtcat gtctcttagg gaaagcagga gcctctctgg agacctttag cagggtcagg 1920 gcccctcacc ttcccctctt ttcccagagc tgtcttccca gcccaccatc cccatcgtgg 1980 gcatcattgc tggcctggtt ctccttggag ctgtgatcac tggagctgtg gtcgctgccg 2040 tgatgtggag gaggaagagc tcaggtggag aaggggtgaa gggtggggtc tgagatttct 2100 tgtctcactg agggttccaa gccccagcta gaaatgtgcc ctgtctcatt actgggaagc 2160 accgtccaca atcatgggcc tacccagtct gggccctgtg tgccagcact tactcttttg 2220 taaagcacct gttaaaatga aggacagatt tatcaccttg attacggcgg tgatgggacc 2280 tgatcccagc agtcacaagt cacaggggaa ggtccctgag gacagacctc aggagggcta 2340 ttggtccagg acccacacct gctttcttca tgtttcctga tcccgccctg ggtctgcagt 2400 cacacatttc tggaaacttc tctggggtcc aagactagga ggttcctcta ggaccttaag 2460 gccctggctc ctttctggta tctcacagga cattttcttc tcacagatag aaaaggaggg 2520 agttacactc aggctgcaag taagtatgaa ggaggctgat gcctgaggtc cttgggatat 2580 tgtgtttggg agcccatggg ggagcccacc cacctcacaa ttcctcctct agccacatct 2640 tctgtgggat ctgaccaggt tctgtttttg ttctacccca ggcagtgaca gtgcccaggg 2700 ctctgatgtg tccctcacag cttgtaaagg tgagagcttg gaggacctaa tgtgtgttgg 2760 gtgttgggcg gaacagtgga cacagctgtg ctatggggtt tctttgcatt ggatgtattg 2820 agcatgcgat gggctgttta aggtgtgacc cctcactgtg atggatatga atttgttcat 2880 gaatattttt ttctatagtg tgagacagct gccttgtgtg ggactgagag gcaagagttg 2940 ttcctgccct tccctttgtg acttgaagaa ccctgacttt gtttctgcaa aggcacctgc 3000 atgtgtctgt gttcgtgtag gcataatgtg aggaggtggg gagaccaccc cacccccatg 3060 tccaccatga ccctcttccc acgctgacct gtgct 3095 //