Trome is an attempt to map transcribed RNA from different sources to the genome. It includes a filtering step that allows the removal of non-trustful data. Moreover regarding the integration process, Trome was designed such that all transcriptional data is mapped to the genome. As an example for Homo sapiens, the transcribed RNA sources are: the human EST section of EMBL, the human HTC section of EMBL, human mRNA documented in the EMBL DB, ORESTES sequences from the LICR/FAPESP Human Cancer Genome project, human mRNA documented in the NCBI curated RefSeq DB, published CHR21 gene list and SEREX sequences. For other species, similar sources are used. Currently only four species are treated: Homo sapiens, Mus musculus, Arabidopsis thaliana and Caenorhabditis elegans.