{"id":338,"date":"2020-10-27T15:43:27","date_gmt":"2020-10-27T15:43:27","guid":{"rendered":"http:\/\/www.ebi.ac.uk\/training\/online\/courses\/reactome-exploring-biological-pathways\/?page_id=338"},"modified":"2020-10-27T15:43:27","modified_gmt":"2020-10-27T15:43:27","slug":"summary","status":"publish","type":"page","link":"https:\/\/www.ebi.ac.uk\/training\/online\/courses\/reactome-exploring-biological-pathways\/summary\/","title":{"rendered":"Summary"},"content":{"rendered":"\n<ul class=\"wp-block-list\"><li>Reactome is a curated database that represents human pathways as interconnected molecular events or &#8216;reactions&#8217;<\/li><li>Reactome broadly defines a reaction as any molecular event in biology, including binding, phosphorylation, catalysed biochemical events, spontaneous molecular events and transport<\/li><li>Reactions can be considered as &#8216;steps&#8217; in a pathway. Pathways are represented as diagrams containing a series of interconnected events, often organised into sub-pathways<\/li><li>Reactome has a hierarchical organization, from &#8216;top-level&#8217; broad topics in biology to lower-level specific pathways and the events they contain.<\/li><li>The core dataset of human pathways is authored by expert biologists and independently peer-reviewed before release<\/li><li>Reactome&#8217;s curated human events are used as templates to computationally infer equivalent pathways in other species, including the most widely used model organisms<\/li><li>Reactions have literature citations that experimentally verify the described event<\/li><li>Reactome uses primary external sources, and extensively cross-references many other relevant sources of biological, chemical and literature information<\/li><li>Reactome hosts a range of pathway analysis tools that can be used to analyse experimental data and compare species\/tissues<\/li><li>External protein interaction data (default IntAct) can be overlaid on Reactome pathways for extended analysis<\/li><li>Reactome data and software are open source, freely available to download and reuse from the website with appropriate citation<\/li><\/ul>\n","protected":false},"excerpt":{"rendered":"<p>Reactome is a curated database that represents human pathways as interconnected molecular events or &#8216;reactions&#8217; Reactome broadly defines a reaction as any molecular event in biology, including binding, phosphorylation, catalysed biochemical events, spontaneous molecular events and transport Reactions can be considered as &#8216;steps&#8217; in a pathway. Pathways are represented as diagrams containing a series of&#8230;<\/p>\n","protected":false},"author":30,"featured_media":0,"parent":0,"menu_order":9,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-338","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/www.ebi.ac.uk\/training\/online\/courses\/reactome-exploring-biological-pathways\/wp-json\/wp\/v2\/pages\/338","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.ebi.ac.uk\/training\/online\/courses\/reactome-exploring-biological-pathways\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.ebi.ac.uk\/training\/online\/courses\/reactome-exploring-biological-pathways\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.ebi.ac.uk\/training\/online\/courses\/reactome-exploring-biological-pathways\/wp-json\/wp\/v2\/users\/30"}],"replies":[{"embeddable":true,"href":"https:\/\/www.ebi.ac.uk\/training\/online\/courses\/reactome-exploring-biological-pathways\/wp-json\/wp\/v2\/comments?post=338"}],"version-history":[{"count":1,"href":"https:\/\/www.ebi.ac.uk\/training\/online\/courses\/reactome-exploring-biological-pathways\/wp-json\/wp\/v2\/pages\/338\/revisions"}],"predecessor-version":[{"id":340,"href":"https:\/\/www.ebi.ac.uk\/training\/online\/courses\/reactome-exploring-biological-pathways\/wp-json\/wp\/v2\/pages\/338\/revisions\/340"}],"wp:attachment":[{"href":"https:\/\/www.ebi.ac.uk\/training\/online\/courses\/reactome-exploring-biological-pathways\/wp-json\/wp\/v2\/media?parent=338"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}