- Course overview
- Search within this course
- What is Open Targets?
- What is the Open Targets Platform?
- Deep dive into common disease genetics data (GWAS and QTL studies)
- Getting data from the Open Targets Platform
- Other informatics tools
- Summary
- Your feedback
- Get help and support on Open Targets’ informatics tools
- References
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Summary
Open Targets
Open Targets is an industry-academia partnership with a portfolio of projects spanning experimental and informatics research for the systematic identification and prioritisation of drug targets.
Open Targets maintains a suite of informatics tools, most prominent of which is the Open Targets Platform.
- Review the ‘What is Open Targets‘ section.
The Open Targets Platform
The Open Targets Platform — platform.opentargets.org — is an open source, freely available tool that aggregates and integrates data from over 20 sources. It allows users to explore target-disease associations, and view the underlying data that supports the associations, as well as a range of annotation data for targets, diseases or phenotypes, and drugs.
- Review ‘The Open Targets Platform‘ section.
You can also use the Platform to dive deeper into the genetic evidence supporting target-disease associations.
- Review ‘Deep dive into common disease genetics data (GWAS and QTL studies)‘ section.
Other informatics tools
Open Targets maintains a number of other resources, including Project SCORE, which allows users to explore the results of our CRISPR-Cas9 whole-genome dropout screens in cancer cell lines, and the eQTL Catalogue, which provides uniformly processed gene expression and splicing eQTLs from all publicly available human studies.
- Review the ‘Other informatics tools‘ section.