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Types of biological networks

Biological networks

Different types of information can be represented in the shape of networks in order to model the cell (Figure 10). The meaning of the nodes and edges used in a network representation depends on the type of data used to build the network and this should be taken into account when analysing it.

Figure 10 Types of biological interactions that can be represented by networks (Adapted with permission from slides by Dr. Nataša Pržulj, Imperial College, London).

Different types of data will also produce different general network characteristics in terms of connectivity, complexity and structure, where edges and nodes potentially convey multiple layers of information.

Some of the most common types of biological networks are:

  1. Protein-protein interaction networks
  2. Metabolic networks
  3. Genetic interaction networks
  4. Gene / transcriptional regulatory networks
  5. Cell signalling networks

Slide the bar below to find further details (Figure 11-15):