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Network analysis of protein interaction data

An introduction

    • Course overview
    • Search within this course
    • Network analysis in biology
    • Introduction to graph theory
      • Graph theory: graph types and edge properties
      • Graph theory: adjacency matrices
      • Try it yourself: adjacency matrices
      • Graph theory: network topology
    • Types of biological networks
    • The sources of data underlying biological networks
    • Protein-protein interaction networks
      • Properties of PPINs: small world effect
      • Properties of PPINs: scale-free networks
      • Properties of PPINs: transitivity
    • Building and analysing PPINs
      • Network representation and analysis tools
      • Sources of PPI data
      • Assessing reliability and measuring confidence
      • Topological PPIN analysis
        • Centrality analysis
        • Closeness centrality
        • Betweenness centrality
        • Clustering analysis
        • Clustering analysis methods I
        • Clustering analysis methods II
      • Annotation enrichment analysis
      • Limitations of annotation enrichment
    • Summary
    • Quiz: Check your learning
    • Your feedback
    • Learn more
    • References

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