Protein sequences and functional annotations at UniProt

UniProt provides the scientific community with a comprehensive, high-quality and freely accessible resource of protein sequence and functional information.

This webinar with Paul Denny (Scientific Database Curator, EMBL-EBI) and Emily Bowler-Barnett (Scientific Database Curator, EMBL-EBI), recorded on 1 November 2023, provides ways in which students and researchers at all career stages may take a structured approach to access the data in the UniProt KnowledgeBase (UniProtKB) section of the UniProt protein function database.

The webinar discusses the types of protein data that can be accessed, and using sequence analysis tools, how this data can be analysed to answer biological questions. It demonstrates how to find the function of a protein, how the protein components of a pathway may be identified, features of proteins of interest can be compared, similar sections of sequence can be sought in other species and how whole data sets containing all the proteins expressed in an organism can be obtained.

Learning outcomes:

By the end of this video you will be able to:

  • Describe what UniProt can be used for
  • Search the UniProt website and analyse protein data

info symbol high res If you want to have more in-depth learning about protein sequence and function, take a look at an online tutorial from UniProt – UniProt: Exploring protein sequence and functional information

After learning about sequence and function of proteins, continue on to learn about protein families and domains in the next section.