- Course overview
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- Introduction
- Methods for exploring newly-annotated species in Ensembl Rapid Release
- Genomic variants
- Discovering biological information from mass spectrometry-based proteomics
- Methods in bioimage analysis
- Collection challenge
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- Further learning
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Methods in building and analysing biological networks
Cells are complex and dynamic systems able to modify their behaviour and their morphology in response to internal or environment-induced cues. Such response is achieved thanks to enzymatic reactions and physical interactions that occur between cellular components such as proteins, genes and molecules. Complex diseases (e.g. cancer), have proven to result from alterations in the capacity of cell components to interact and communicate.
This webinar with Livia Perfetto (Senior project coordinator, Human Technopole), recorded on 20 April 2022, provides:
- An introduction to biological networks: conceptual and intuitive framework to investigate, visualise and understand this complex web of interactions.
- An overview of applications of basic graph theory concepts to physical or signalling interaction networks.
- A description of open-access repositories that capture, organise and display physical and signalling interactions.
- An introduction to Cytoscape, an open source software platform for querying public databases and for visualising and analysing networks.
By the end of the webinar recording you will be able to:
- Identify the difference between different types of biological networks
- Describe basic graph theory concepts
- Find more about how to build a biological network by querying public repositories
- Explore Cytoscape, a tool for Network Visualisation and analysis