- Course overview
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- Introduction
- Methods for exploring newly-annotated species in Ensembl Rapid Release
- Genomic variants
- Discovering biological information from mass spectrometry-based proteomics
- Methods in bioimage analysis
- Collection challenge
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Exploring Gene Ontology, GO annotations, tools and resources
The Gene Ontology (GO) resource is the world’s most comprehensive source of information about the function of gene products (proteins and non-coding RNAs). The GO consists of two main components: an ontology of terms that describe biological phenomena and annotations that connect gene products to ontology terms. In addition, GO develops tools to help researchers make use of the GO in their analyses.
This webinar with Antonia Lock (Scientific database curator, EMBL-EBI), recorded on 02 March 2022, provides an overview of what GO terms are and how they relate within the structure of the ontology. It also describes how annotations are created and highlights some of the limitations of the GO. In addition, it introduces some freely available bioinformatic resources used for accessing the GO, and methods used in GO analysis
By the end of this webinar recording you will be able to:
- Explain what the gene ontology is, and its limitations
- Explore where to access GO annotations
- Identify tools and methods used in GO analysis
After having learned about characterising your favourite genes/gene products via functional annotations, you will find approaches for discovering biological information by using protein-protein interaction networks on the next chapter.