- Course overview
- Search within this course
- Introduction
- Functional genomics
- Proteomics
- Metabolomics
- Bioimage data for spatial omics
- Data integration for drug discovery
- Collection quiz
- Share your favourite tools and resources
- Collection completed!
- Your feedback
All materials are free cultural works licensed under a Creative Commons Attribution 4.0 International (CC BY 4.0) license, except where further licensing details are provided.
Gene Ontology
The Gene Ontology (GO) is a dynamic controlled vocabulary that characterises our knowledge of the biological domain in terms of three ontologies: biological processes, molecular functions, and the cellular components of a cell. It assists in making sense of large-scale omics data and formulating mechanistic hypotheses to describe the findings from an experimental study.
This webinar recording with Antonia Lock, Scientific Database Curator, recorded on 2 March 2022, provides an overview of what GO terms are and how they relate within the structure of the ontology. It also describes how annotations are created and highlight some of the limitations of the GO. Lastly it introduces some freely available bioinformatic resources used for accessing the GO, and methods used in GO analysis.
Learning outcomes
By the end of this video you will be able to:
- Explain what the gene ontology is, and its limitations
- Explore where to access GO annotations
- Identify tools and methods used in GO analysis
Why not explore more about GO and relevant resources Gene Ontology Annotation (GOA) and QuickGO by going through this online tutorial – ‘GOA and QuickGO: Quick tour‘.