- Course overview
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- What is phylogenetics?
- Why is phylogenetics important?
- What is a phylogeny?
- Major stages in phylogenetic analyses
- Phylogenetics resources at EMBL-EBI
- Discovering the phylogeny of all flowering plants
- Summary
- Quiz: test your knowledge
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- References
Phylogenetics resources at EMBL-EBI
EMBL-EBI offers a range of tools and resources that are relevant to the field of phylogenetics:
- Ensembl: is a vast resource for vertebrate genome data, where (among other things) you can download nucleotide sequence data and run BLAST searches to inform the identification of homologous sequences. For many genes, you can also download the orthologous sequences that we have identified, as well as interspecific alignments that we have pre-computed. To do so, simply search for your favourite gene (e.g. ADH1B), and explore the ‘genomic alignments’ options within the comparative genomics menu.
- Ensembl genomes: extends Ensembl across the tree of life, making genome data publically available for Bacteria, Plants, Fungi, Protists and Metazoa. This includes pre-computed alignments and orthologues.
- Ensembl compara: offers pre-computed phylogenies for visualisation and download. For further information see the documentation page.
- EMBL-EBI Job Dispatcher: this includes multiple tools such as ClustalW2 for Phylogenetic tree generation and EMBOSS tools for sequence analysis.