Human genetic variation
Exploring publicly available data
Genetic variation is fundamental to the evolution of all species and is what makes us individuals. Our genes have a large influence on our lives. They affect what we look like, our personalities and preferences and our susceptibility to disease. By studying genetic variation we hope to understand the molecular processes that contribute to life on earth.
Who is this course for?
The courses focus on heritable (germline) variation and will give you a taste of the resources you can use to explore genetic variation data. An undergraduate knowledge of biology would be an advantage.
This is part II of our course on human genetic variation. Part I of the course introduces some key concepts in the field of human genetic variation including the types and possible effects of genetic variation, data formats and look common genetic variation study types. If you are new to the field we recommend that you work through part I of this course first.
What will I achieve?
By the end of the course you will be able to:
- List examples of genetic variation databases
- Describe the type of data found in different genetic variation databases
- Explore genetic variation data within publicly available resources
What resources do I need?
There are no specific resources required to complete this course.
- Introduction to public genetic variation data
- Case study 1: variants in a gene (PKD1)
- Cast study 2: Search for a variant (rs334)
- Case study 3: Search for a phenotype (non-melanoma skin cancer)
- Case study 4: Starting with the literature
- Your feedback
How and when to access the course
All our courses are designed with flexibility in mind. You can access them for free at any time, just click on the “Enter Course” button.
It is up to you how you use the course; you can either study the full course or you can focus on sections that are relevant to you. To jump between sections, use the navigation bar on the left or the arrows at the bottom of the page. You can also choose whether to complete the course in one go, or over several visits.
The average time to read through the main body of the course is 2 hours (not including exercises and external links). The time may vary depending on your prior knowledge and how you choose to work through the course.
Making the most of the course
Learning something new takes time and practice. We encourage you to:
- Use the activities and quizzes to help you check your learning, recall and apply key concepts. Look out for these icons:-
Activities Quizzes Videos
- Revisit sections as and when you need them. Bookmark relevant pages in your browser or use the navigation panel to jump the relevant section.
Getting help and providing feedback
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