What does Genome Properties contain?

There are six different types of Genome Properties entries:

• PATHWAY – Enzymatic pathways, each step within the property is an enzyme
• SYSTEM – Similar to pathways, but can include non-enzymatic steps
• METAPATH – Pathways or systems where one or more steps can be represented by another Genome Property
• GUILD – Groups of related proteins without a defined sequence of function
• COMPLEX – Stable macromolecular complexes
• CATEGORY – Organisational properties, used to classify the other properties into a hierarchy

Genome Properties was originally developed within the TIGRFAMs resource, using their protein family models to describe predominantly prokaryotic properties. Since being established within InterPro, we have sought to expand the coverage using two main approaches. The creation of eukaryotic properties (based on published descriptions of pathways in the literature), and the automated import of properties from relevant resources such as MetaCyc and the Complex Portal.