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Macromolecules
The macromolecules refer to relevant molecules that form the core of deposited 3D structures. These typically include proteins, nucleic acids (DNA and RNA), and their complexes. Each macromolecule entry is annotated with its sequence, chemical composition, 3D coordinates, and cross-references to external resources such as UniProt, Pfam, and other biological databases that provide functional and biological context.
Where to find it?
Information about macromolecules is available in the Macromolecules tab (see below):
- Left-hand section: lists all macromolecules present in the 3D structure (excluding small molecules such as ligands or ions). It allows you to update the displayed information (source organism, UniProt mapping, theoretical weight, etc.) as well as the sequence, which is shown in 1D and 2D layouts, and in the interactive 3D viewer.
- Filter labels (e.g. “8 distinct proteins”, “1 DNA or RNA”) let you adjust the list according to the selected category.
- Macromolecule labels (e.g. “Chromatin modification-related protein EAF6”) open detailed descriptions, including source organism, UniProt mapping, theoretical weight, and sequence.
Main section: displays the selected macromolecule in multiple representations — sequence in 1D, structural features in 2D, and the 3D coordinates in the interactive viewer.
