Comparing genomes
The Ensembl comparative genomics analyses (Ensembl Compara) are applied to all domains within Ensembl and Ensembl Genomes.
The DNA comparison modules are suitable for use over a narrow taxonomic range. They can be used to support multiple sequence alignments and to make predictions of ancestral DNA sequences (Figure 4).
The protein comparison modules compute the evolutionary history of a gene familiy. They can be applied over much larger evolutionary distances. A ‘gene tree’ provides a summary of this information as well as the anchor point for outward links to pairwise and multiple-sequence alignments and orthologue/paralogue lists.
