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How to get data from UniProt

There are a number of different ways to access UniProt data including:

  • downloading data from the UniProt FTP site
  • downloading small data sets from the UniProt web site
  • accessing the resource programmatically

Downloading complete data sets

You can download the entire UniProtKB, UniRef and UniParc databases. For downloading these complete data sets, we recommend that you use the UniProt FTP site.  Please use a tool that makes use of the HTTP protocol’s If-Modified-Since header to avoid more than one download per release. If you are located in Europe, the Middle East or Africa, you may find it faster to download data from our mirror sites in the United Kingdom or Switzerland instead.

Downloading subsets of data

You can download small data sets and subsets directly from the UniProt web site by following the download link on any search result page. This will allow you to download data in a range of formats including FASTA, tab-delimited, text, Excel, GFF, XML and RDF/XML (Figure 50).

Figure 50 Use the ‘Download’ button to download data sets directly from the web site.