Pablo Porras got his PhD in 2006 in the University of Córdoba, Spain, having done research about trans-membrane protein translocation and redox homeostasis. After that, he moved to Berlin to work in the Neuroproteomics group of the Max Delbrueck Center, getting involved in projects dealing with interactomics, neurodegenerative diseases and the ubiquitin-proteasome system. During this postdoc, he faced the problem of how to represent and analyze molecular interactions data. This experience proved to be of great value once he joined the EBI to work as a scientific curator in the molecular interactions database IntAct in 2011.
Matt Rogon completed his MSc in Molecular Biology at the University of Gdansk, Poland. After working for 3 years as an editor for an online education publishing house he switched his focus to Bioinformatics (MRes at Glasgow University, UK) and followed up with a PhD in Systems Biology at the German Cancer Research Center (DKFZ) and the University of Heidelberg, Germany. After a short postdoc he joined EMBL in 2013. He is coordinating the EMBL Centre for Biomolecular Network Analysis with a focus on consulting, project support, and teaching in the field of Network Biology and data integration.
I am interested on disentangling the complexity of biological systems at different levels, generating data-driven hypotheses to explore the fundamental basis of disease, development, variability and evolution. My PhD research in Florencio Pazos’s group at CNB-CSIC focused on improving computational methods for predicting protein-protein interactions based on coevolution. These methods are founded on the idea that interacting or functionally related proteins tend to adapt to each other during the evolutionary process. As part of my post-doctoral research in the Beltrao group, I study the dynamics, specificity and functional relevance of post-translational modifications. Thanks to the rapidly growing volumes of proteomic data in recent years, the comparative analysis of genome-wide modification sites can provide deeper insights into the specificity and evolution of the regulatory mechanisms of protein activity.