What is the IMPC?

The International Mouse Phenotyping Consortium (IMPC) is building the first truly comprehensive catalogue of a mammalian genome by creating and characterising 20,000 knockout mouse strains - one for every protein-coding gene in the mouse genome (Figure 1). 

The goals of the International Mouse Phenotyping Consortium

Figure 1 The main goals of the International Mouse Phenotyping Consortium. 

The IMPC has developed a free to access portal which provides data on phenotypes, disease models and protocols, as well as links to repositories where you can order these newly created mouse strains.

When to use the IMPC portal

The IMPC portal allows you to:

  • Determine what phenotypes and diseases are associated with your gene of interest;
  • Search for available knockout mouse strains and order them;
  • Evaluate mouse models that exhibit a specific phenotype or disease;
  • Find information on a range of different phenotyping protocols.