RNA-Seq Ensembl gene build


This lecture is by Simon White of Ensembl.

In it, he explains how we can use RNA-Seq data to annotate genomes, including building complete gene sets from scratch, adding novel genes to existing annotations, improving and validating existing annotations and analysing the UTRs of genes. He explains the methods involved in RNA-Seq genome annotation.

He discusses the impact that this has had on the annotation of already annotated genomes, using the example of zebrafish, and on creating annotation for new genomes, in this case the Tasmanian devil.