Searching for potent bioactivities by substructure

 

Scenario

Imagine that you want to find all the potent bioactivities for compounds in ChEMBL which have the same substructure:

substructure

Exercise

Use ChEMBL and the compound structure drawing window to search for your substructure of interest and then filter on an IC50 of less than 10000nM.

Note: The units of nM are implied and you don't need to type them in.