Where does the data come from?

Chemical entities curated into ChEBI originate from a variety of sources, including:

  • Automatic loading of data from selected resources, such as the Ligand section of the Kyoto Encyclopedia of Genes and Genomes (KEGG Compound), the Human Metabolome Database (HMDB), etc;
  • Data annotated elsewhere (e.g. user submissions), which are subsequently checked and updated by ChEBI curators;
  • Manual annotation by the ChEBI team, covering a variety of requests from users via the ChEBI SourceForge channel, user emails, etc.

The ChEBI star rating system

  •  Preliminary data gets 1 star and is not normally displayed on the ChEBI website.
  •  Data from externally curated sources (e.g. imported from KEGG) but not yet checked by ChEBI gets 2 stars and appears "as is" on the ChEBI website.
  •  After an entry has been updated with additional links, cross-references, etc, and checked by a member of ChEBI curation team, it is upgraded to 3 stars.