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Structural biology data and sequences
Sequences, families and folds
Macromolecular structure databases, tools and visualisation
Protein structure prediction and molecular docking
Bioactive molecules and disorder
- Ligand structural biology with ChEMBL
- AI to predict disordered proteins
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Completing predicted structures using AlphaFill and AlphaBridge

Trainer: Robbie Joosten

Overview:

This lecture provides an introduction to AlphaFill and AlphaBridge software for completing AlphaFold-predicted protein structures by predicting and adding cofactors, ions and other small molecules.

Learning outcomes:

By the end of this session you will be able to:

Complete AI-predicted protein structures using AlphaFill and AlphaBridge

Materials: Link to PDF slides

Link to practical PDF

Recorded lecture:

Structural bioinformatics

Completing predicted structures using AlphaFill and AlphaBridge