Overview
Search
Course content
Structural biology data and sequences
- Introduction to structural biology data
- Sequences: Alignments and Annotation
Sequences, families and folds
Macromolecular structure databases, tools and visualisation
Protein structure prediction and molecular docking
Bioactive molecules and disorder
- Ligand structural biology with ChEMBL
- AI to predict disordered proteins
Technical help sheets
Course organisers
Trainer biographies
Further learning
Your feedback

Completing predicted structures using AlphaFill

Trainer: Robbie Joosten

Overview:

This lecture provides an introduction to AlphaFill software for completing AlphaFold-predicted protein structures by predicting and adding cofactors, ions and other small molecules.

Learning outcomes:

By the end of this session you will be able to:

Complete AI-predicted protein structures using AlphaFill

Materials

Link to presentation slides and PDF

Link to practical document and PDF

Recorded lecture:

Structural bioinformatics

Completing predicted structures using AlphaFill