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Structural bioinformatics

  • Overview
  • Search
  • Course content
  • Structural biology data and sequences
    • Introduction to structural biology data
    • Sequences: Alignments and Annotation
  • Sequences, families and folds
    • Sequence classification: Pfam and InterPro
    • CATH DB – Protein folds and structural family resources
    • Structural informatics: Past and present
  • Macromolecular structure databases, tools and visualisation
    • Structure validation and PDB-Redo
    • PDBe and Molstar
    • PDBe-KnowledgeBase
    • EMDB
    • Molecular visualisation for Structural biology
  • Protein structure prediction and molecular docking
    • Modelling protein structure and missense variants: Phyre2 and Missense3D in the context of AlphaFold models
    • AlphaFold Database and ColabFold
    • Completing predicted structures using AlphaFill
    • Exploring protein docking with HADDOCK
  • Bioactive molecules and disorder
    • Ligand structural biology with ChEMBL
    • AI to predict disordered proteins
  • Technical help sheets
  • Course organisers
  • Trainer biographies
  • Further learning
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EMDB

Trainers: Jack Turner

Overview: In this lecture and practical a comprehensive rundown of the electron microscopy database EMDB is covered.

Materials:

  • Link to EM presentation slides
  • Link to EMDB and visualisation slides
  • Link to validation slides
  • Link to EMDB tutorial sheet
  • Link to EMDB tutorial answers
  • Link to EM data

  • Recorded lecture:
  • page navigation-left-circle-1_1 PDBe-KnowledgeBase
  • pageMolecular visualisation for Structural biology navigation-right-circle-1_1