Open Targets Platform: Integrating human data for drug discovery

Trainers: Annalisa Buniello, Helena Cornu

Overview: This session was part of the 2023 iteration of the ‘Introduction to RNA-Seq and functional interpretation’ course. It provides an overview of the Open Targets Platform, a freely available resource that supports systematic identification and prioritisation of potential therapeutic drug targets.‌ By integrating publicly available datasets along with data generated by the Open Targets consortium, the Platform builds and scores target-disease associations. Users can also explore relevant annotation information about targets, diseases, phenotypes, and drugs, as well as their most relevant relationships.

Materials:

Learning outcomes

After this section you should be able to:

  • Describe the knowledge contained in the Open Targets Platform
  • Perform some use-cases analysis