UniProt

Trainer: Yvonne Lussi

Overview: During this section, learn how to navigate UniProtKB to access information on human protein variants, their impact on protein function and structure, as well as their disease involvement, including available literature. Ways to search for a specific disease or a protein variant will be shown, as well as how to identify orthologous proteins and find knockout/knockdown and mutagenesis information in model organisms.

Learning outcomes:

After this section you should be able to:

• Access variant information in UniProt

Materials:

• Accessing human protein variant and disease information in UniProtKB slides