Course content

These materials were part of the live ‘Gene-environmental interactions in human health and disease’ course. Please refer to the course page and programme of the last edition of this course, in March 2025, to check details about this live event and the original programme.

The content table below outlines the different sessions that were included in the course, as well as the format of the materials (slides/videos/practicals) and each session’s trainer. Either proceed through the materials using the arrows at the end of each page or pick your topic of interest from the table below to skip straight to it.

 Presentation slides –  View or download the slides

 Practicals – View or download the slides, exercises, datasets, analysis scripts and results

FormatSubjectTrainer
Introduction to EMBL-EBIHarry Roussos
Understanding and accessing human cohort datasets

An introduction to the exposomeAmy Foreman
From principles to practice: promoting the ethical use of sensitive human dataGiorgia Renne
Accessing health data: real world implementation of health data management Emily Jefferson
EGA as a resource for human cohort datasets Gabriele Rinck
Accessing and utilising large-scale cohort datasetsAlison Motsinger-Reif
Identifying Genomic Associations in Human Cohorts
GWAS catalogElliot Sollis and Santhi Ramachandran
GWAS data analysisTomas Fitzgerald
Open Targets – Exploring the impact of genetic variation on drug responseIrene Lopez and Helena Cornu
Polygenic risk scoresSamuel Lambert
The Impact of Environmental Factors on Aging and NeurodegenerationNatàlia Vilor-Tejedor
Integrated omics, epi-genomics, and biological age, practical part oneOliver Stegle and Marc Bonder
Multiomics methods to understand gene-environment  interactionsLea Maitre
Understanding Causation – identifying Molecular Mechanisms
Bioinformatic Analysis of Functional Genomic Screening in Human CellsPu Xia
The Exposome and Health: Where Chemistry meets BiologyRoel Vermeulen
Novel methods for exposure modelling to assess the external urban exposomeKees de Hoogh
Exposures and cancer Epigenetics  Talya Dayton