Multiple ways to integrate multi-omics data – case studies from studying human diseases
Trainers: Tamás Korcsmáros and Matthew Madgwick
Overview: The presentation covers why it is useful to use protein-protein interaction networks, and the advantages of combining them with regulatory and metabolic interactions. We discuss intra- and inter-cellular signaling, and what are the most useful resources available to analyse your own data. Then four network medicine examples will demonstrate multi-omics integration in the field of infectious, cancerous and inflammatory diseases.
Learning outcome
By the end of this session you will be able to:
- Describe key application areas and methods in Network Medicine and biology driven multi-omics data integration.
- Define the main data sources for Network Medicine
- Summarise the main challenges and limitations with using networks
- Apply the knowledge to other projects
- Discuss some advantages of Network and Precision Medicine in therapy selection and drug repurposing
Materials: