Recorded webinar

Exploring somatic mutations in cancer with the COSMIC database and analysis tools

COSMIC (the Catalogue of Somatic Mutations in Cancer) helps the global cancer research community conduct their science faster and better by presenting easy to understand, streamlined, and quality filtered data on cancer mutations. We do this by providing high quality datasets curated by experts over the course of 18 years, standardising our data into easily-integrable formats, and innovating with collaborators to provide analysis tools and actionable insights.

With 23 million genomic variants, expertly curated from nearly 30,000 publications, covering 6,800 precise forms of human cancer, COSMIC is the world’s largest manually curated database of somatic mutation information relating to human cancers. This vast breadth and depth of high quality data is the gold standard, relied upon by academic research and industry alike, including pharmaceutical, drug discovery and biotech companies.

This webinar will provide an introduction to COSMIC, our process, and demonstrate the vast range of data and analyses available via our multiple tools and projects. We will focus particularly on two of our newer projects: Cancer Mutation Census and Actionability, which will be freely available for non-commercial download as of 29 November 2022. We will also provide an opportunity for questions and hope that by the end of the webinar, you will feel confident in exploring COSMIC’s tools and understand how they can add value to your work.

Who is this course for?

This webinar is aimed at early-career researchers and students who are interested in cancer genetics and bioinformatics. It would suit anyone who is new to COSMIC or people who want to explore the full depth of COSMIC.


By the end of the webinar you will be able to:

  • Describe the depth and breadth of data within COSMIC
  • Identify how COSMIC data can be used to add value to your work
  • Explore COSMIC’s datasets and webpages

DOI_disc_logo DOI: 10.6019/TOL.cosmic22-w.2022.00001.1

This webinar took place on 14th December 2022. Please click the 'Watch video' button to view the recording.

Duration: 00:51:44
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14 December 2022
Ajay Mishra


  • Rebecca White
    Wellcome Sanger Institute
  • Steven Jupe
    Wellcome Sanger Institute
  • Jennifer Wilding
    Wellcome Sanger Institute
  • Michael Starkey
    Wellcome Sanger Institute
  • Helder Pedro
    Wellcome Sanger Institute

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All materials are free cultural works licensed under a Creative Commons Attribution 4.0 International (CC BY 4.0) license, except where further licensing details are provided.

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