Course at EMBL-EBI
Bioinformatics resources for protein biology
Are you aware of the wide range of protein data resources that can easily be accessed and explored to enhance your research? Do you want to know more about the sequence of your protein and its functions? Wondered whether a structure of your protein exists and how to explore it? Want to know more about the potential complexes and reaction pathways your protein of interest is involved in, giving you a better overview of its biological context?
This three day course will introduce you to data resources and tools developed by EMBL-EBI that can help you in your protein studies. Each day will focus on a particular protein topic, with the aim of helping you get more from your data and also to explore publically-available data that can further support your research. On the last day you will have the opportunity to either explore the data resources presented in the course further, tackling a biologically relevant problem, or to learn how to access some of the EMBL-EBI resources and tools programmatically.
Course topics:
- Day 1: Where can I find protein sequence, classification and comparison information?
- Day 2: How do I choose a “good” protein structure and what can I learn from it?
- Day 3: What interactions, complexes and pathways is my protein involved in?
Who is this course for?
This course is aimed at anyone interested in finding out more about protein biology. No prior experience of bioinformatics is required, but participants should have an undergraduate level understanding of biology.
For those who wish to attend the session on programmatic access a prior knowledge of coding/programming would be of benefit. For an introduction to the concept of web services and how you can use them to access the tools and data available at EMBL-EBI please watch our webinar.
What will I learn?
Learning outcomes
After this course you should be able to:
- Access and explore a range of appropriate protein resources
- Use these resources to retrieve relevant protein information
- Apply the information you have discovered in your research
Course content
During this course you will learn about:
- UniProtKB, InterPro, HMMER on day 1
- PDBe, EMDB on day 2
- IntAct, Complex Portal, Reactome on day 3
Trainers
Alexandra Holinski
EMBL-EBI, UK Sara El-Gebali
EMBL-EBI, UK Lorna Richardson
EMBL-EBI, UK David Armstrong
EMBL-EBI, UK Osman Salih
EMBL-EBI, UK Birgit Meldal
EMBL-EBI, UK Thawfeek Mohamed Varusai
EMBL-EBI, UK Rossana Zaru
EMBL-EBI, UK Hema Bye-A-Jee
EMBL-EBI, UK
EMBL-EBI, UK
EMBL-EBI, UK
EMBL-EBI, UK
EMBL-EBI, UK
EMBL-EBI, UK
EMBL-EBI, UK
EMBL-EBI, UK
EMBL-EBI, UK
EMBL-EBI, UK
Programme
Day 1 – Tuesday 26 February 2019 |
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Where can I find protein sequence, classification and comparison information? | ||
08:15 | Shuttle from Cambridge Station | |
09:00-9:15 | Arrival and registration | |
09:15-9:30 | Welcome and introduction | Alexandra Holinski |
09:30-11:00 | UniProt | Rossana Zaru, Hema Bye-A-Jee |
11:00-11:15 | Break | |
11:15-12:45 | UniProt | Rossana Zaru, Hema Bye-A-Jee |
12:45-13:30 | Lunch | |
13:30-15:15 | HMMER | Sara El-Gebali |
15:15-15:30 | Break | |
15:30-17:00 | InterPro | Lorna Richardson |
17:15 | Shuttle to Cambridge Station | |
Day 2 – Wednesday 27 February 2019 |
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How do I choose a "good" protein structure and what can I learn from it? | ||
08:15 | Coach from Cambridge Train Station | |
09:00-10:30 | PDBe: Introduction and search | David Armstrong |
10:30-11:00 | Break | |
11:00-12:15 | PDBe: Entry pages and validation | David Armstrong |
12:15-13:15 | Lunch | |
13:15-14:30 | PDBe tools | David Armstrong |
14:30-15:00 | Break | |
15:00-17:00 | Electron Microscopy DataBank (EMDB) | Osman Salih |
17:15 | Shuttle to Cambridge Station | |
Day 3 – Thursday 28 February 2019 |
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What interactions, complexes and pathways is my protein involved in? | ||
08:15 | Coach from Cambridge Train Station | |
09:00-10:30 | Molecular Interactions | Birgit Meldal |
10:30-10:45 | Tea/coffee Break | |
10:45-12:15 | Molecular Interactions | Birgit Meldal |
12:15-12:45 | Lunch | |
12:45-14:15 | Reactome | Thawfeek Mohamed Varusai |
14:15-14:30 | Break | |
14:30-16:00 | Reactome | Thawfeek Mohamed Varusai |
16:00-17:00 | Exploring EMBL-EBI data resources (additional hands-on session) | All |
17:00-17:15 | Wrap up and feedback | Alexandra Holinski |
17:30 | Shuttle to Cambridge Station |
Attendance at this workshop is allocated on a first come, first served basis.
The registration fee covers your lunch, refreshments and a shuttle between Cambridge Station and the Wellcome Genome Campus. Accommodation is not included and you will need to make your own arrangements.
Please note that registration closes two weeks prior to the course, so please register as soon as you can. Once you have registered and we have received payment we can provide a letter of support should you require a visa to travel to the UK. Applying for a visa can take several weeks, and it might not be possible to be granted a visa if you register just before the closing date. If you are unable to attend, then please notify us as quickly as possible so that we can offer your place to someone else.
Once you have registered please send Marina Pujol (mpujol@ebi.ac.uk) a picture of yourself and a Microsoft Word (.docx) document containing three short paragraphs with a biography, work history and description of your current research interests; each paragraph should be no more than 100 words.