3D-BioInfo Community Annual Meeting

Date:

 Thursday 21 Friday 22 November 2019

Venue: 

European Bioinformatics Institute (EMBL-EBI) - Wellcome Genome Campus, Hinxton, Cambridge,  CB10 1SD, United Kingdom

Application opens: 

Friday 16 August 2019

Application deadline: 

Friday 01 November 2019

Participation: 

First come, first served

Contact: 

Charlotte Pearton

Registration fee: 

£50

Overview

ELIXIR Communities enable the participation of communities of practice in different areas of the life sciences in the activities of ELIXIR, which underpin the evolution of a data, tools, interoperability, compute and training infrastructure for European life science informatics (https://www.elixir-europe.org/use-cases).

Structural bioinformatics has a broad impact across the life sciences and provides tools to archive, visualise, analyse, annotate, and predict the structure of biological macromolecules. Structural bioinformatics is traditionally very strong in Europe offering many software tools, methodologies, and databases, as well as community-wide prediction challenges.

Its applications cover research activities from structural biology to drug discovery and personalised medicine that are all well represented within the national ELIXIR nodes.

The 3D-BioInfo Community was approved by ELIXIR in May 2019. This meeting will be the first official meeting of the community to plan major activities and to identify research groups wishing to contribute to these activities.

Programme

Thursday

The workshop will begin at 12pm.

  • Plenary session and overview of 3D-BioInfo plans
  • Parallel breakout sessions on the four activity areas
  • Discussion on a possible Protein Engineering ‘Activity’

Friday

The workshop will finish by 4pm.

  • Report back from the breakout sessions
  • Keynote lecture from John Briggs
  • Discussion on interaction with the Instruct Community

The Thursday of the workshop will be divided into four sessions focusing on the themes of the four major Activities of 3D-BioInfo. Please indicate which session you wish to attend when registering.

Infrastructure for FAIR structural and functional annotations

Coordinator: Sameer Velankar

  • Discuss benchmarking of prediction of ligand binding sites
  • Practical session on data submision system and on exploiting PDBe-KB data

Open resources for sharing, integrating and benchmarking software tools for modelling the proteome in 3D

Coordinator: Shoshana Wodak

  • Review & evaluate available tools and resources for curating data on structures of macromolecular complexes in the PDB. This ‘review’ will include tools for annotating protein interfaces
  • Discuss strategies for organizing the information on macromolecular complexes in the PDB, to facilitate deriving benchmark datasets for various applications

Protein-ligand interactions

Coordinator: Vincent Zoete

  • Identify, review and evaluate tools, resources and databases available for curation of a large-scale fundamental-research centric benchmark set of ligand-biomacromolecule complexes, along with ligand and protein annotations
  • Discuss strategies for creating the benchmark set, realistic deliverables and a plan to achieve this with limited resources.

Tools to Describe, Analyse, Annotate, and Predict Nucleic Acid (NA) Structures

Coordinator: Bohdan Schneider

  • Review the tools and resources available for critical areas in the NA structure analysis
  • Discuss strategies for future activities.

Audience

This workshop is aimed at members and collaborators of the 3D-BioInfo Community.

Outcomes

This workshop will help the 3D-BioInfo Community plan their major activities and identify research groups willing to contribute towards these activities.

Additional information

Accommodation is not provided for this workshop and participants will need to arrange this for themselves. We reccommend booking at the Wellcome Genome Campus Conference Centre on site. Please book as early as you can as space can be limited. For other recommendations in the local area please see: //www.ebi.ac.uk/about/contact.

If there is sufficient interest from participants we can arrange a shuttle between Station Road, Cambridge and the campus each day. This will be of use to Cambridge residents or visitors choosing to stay in the city for the duration of the workshop.

Programme

Thursday

The workshop will begin at 12pm.

  • Plenary session and overview of 3D-BioInfo plans
  • Parallel breakout sessions on the four activity areas
  • Discussion on a possible Protein Engineering ‘Activity’

Friday

The workshop will finish by 4pm.

  • Report back from the breakout sessions
  • Keynote lecture from John Briggs
  • Discussion on interaction with the Instruct Community