This module introduces the area of sequence similarity searching and focuses on how to use tools like BLAST and PSI-Search to find homologous sequences in EMBL-EBI databases, including tips on which tool and database to use, input formats, how to change parameters and how to interpret the results pages.
The module is designed for researchers who need to undertake sequence searching as part of their work. No previous bioinformatics experience is required, but an undergraduate level knowledge of biology would be an advantage.
Modules and resources
Web-based pairwise sequence alignment tools and Web-based sequence similarity search tools such as BLAST, FASTA, PSI-BLAST, PSI-SEARCH
Participants should be able to:
- describe the basics of sequence similarity searching and sequence homology
- identify related biological sequence data across EMBL-EBI resources
- use different sequence similarity tools and select appropriate tools for different applications.
This course runs from 13:30-17:30 including breaks.