Tyrosine phenol-lyase (M-CSA:933)

Proteins that are close homologues to the M-CSA reference protein and have the same catalytic residues (highlighted in green, below) probably share the same mechanism. Please also check if the homologue shares the same FunTree Structural Cluster and the same Pfam family, as another measure of similarity.

Legend:
Reference Residue Conserved Residue Non Conserved Residue Outside Alignment Reference Residue not in this sequence

Homologous SwissProt sequences of P31013

Reference Sequence Homologue Phe448 Tyr71 Lys257 Thr124 Phe123 Asp214 Arg381
P31013
FunTreePfam
P28796
FunTreePfam
His458 Tyr72 Lys266 Asp133 Phe132 Asp223 Ile391
P31013
FunTreePfam
P31013
FunTreePfam
Phe448 Tyr71 Lys257 Thr124 Phe123 Asp214 Arg381
P31013
FunTreePfam
A2EYC4
FunTreePfam
His449 Tyr72 Lys257 Asp125 Phe124 Asp214 Ile381
P31013
FunTreePfam
P31015
FunTreePfam
His446 Tyr70 Lys255 Asp124 Phe123 Asp212 Val379
P31013
FunTreePfam
P31014
FunTreePfam
His446 Tyr70 Lys255 Asp124 Phe123 Asp212 Val379
P31013
FunTreePfam
A0KJP3
FunTreePfam
His453 Tyr71 Lys261 Asp128 Phe127 Asp218 Ile386
P31013
FunTreePfam
B0UTZ3
FunTreePfam
His463 Tyr74 Lys270 Asp137 Phe136 Asp227 Ile396
P31013
FunTreePfam
Q9HMV2
FunTreePfam
His439 Tyr67 Lys253 Asp120 Phe119 Asp210 Leu378
P31013
FunTreePfam
Q9CMK9
FunTreePfam
Phe449 Tyr72 Lys258 Thr125 Phe124 Asp215 Arg382
P31013
FunTreePfam
B2J908
FunTreePfam
Phe459 Tyr82 Lys268 Thr135 Phe134 Asp225 Arg392
P31013
FunTreePfam
Q897C2
FunTreePfam
Phe451 Tyr74 Lys260 Thr127 Phe126 Asp217 Arg384
P31013
FunTreePfam
Q729Z3
FunTreePfam
His453 Tyr71 Lys261 Asp128 Phe127 Asp218 Ile386
P31013
FunTreePfam
Q8RHM6
FunTreePfam
Phe451 Tyr74 Lys260 Thr127 Phe126 Asp217 Arg384
P31013
FunTreePfam
Q87JQ6
FunTreePfam
His457 Tyr71 Lys265 Asp132 Phe131 Asp222 Ile390
P31013
FunTreePfam
Q54UE3
FunTreePfam
not aligned not aligned Lys32 not aligned not aligned not aligned Ile156
P31013
FunTreePfam
Q9CL27
FunTreePfam
His463 Tyr74 Lys270 Asp137 Phe136 Asp227 Ile396
P31013
FunTreePfam
Q7MCR1
FunTreePfam
His463 Tyr74 Lys270 Asp137 Phe136 Asp227 Ile396
P31013
FunTreePfam
Q08897
FunTreePfam
Phe449 Tyr72 Lys258 Thr125 Phe124 Asp215 Arg382
P31013
FunTreePfam
P0A853
FunTreePfam
His463 Tyr74 Lys270 Asp137 Phe136 Asp227 Ile396
P31013
FunTreePfam
Q7NYV9
FunTreePfam
His453 Tyr72 Lys261 Asp129 Phe128 Asp218 Ile386
P31013
FunTreePfam
D9R201
FunTreePfam
Phe452 Tyr74 Lys260 Thr127 Phe126 Asp217 Arg385
P31013
FunTreePfam
Q8R9K5
FunTreePfam
His453 Tyr75 Lys261 Asp128 Phe127 Asp218 Val386
P31013
FunTreePfam
Q894M8
FunTreePfam
His463 Tyr85 Lys271 Asp138 Phe137 Asp228 Ile396
P31013
FunTreePfam
Q9KN05
FunTreePfam
His463 Tyr74 Lys270 Asp137 Phe136 Asp227 Ile396
P31013
FunTreePfam
A8AKE2
FunTreePfam
His453 Tyr71 Lys261 Asp128 Phe127 Asp218 Ile386
P31013
FunTreePfam
Q2S1V4
FunTreePfam
His446 Tyr71 Lys256 Asp124 Phe123 Asp213 Ile380
P31013
FunTreePfam
Q7N8C9
FunTreePfam
His457 Tyr71 Lys265 Asp132 Phe131 Asp222 Ile390
P31013
FunTreePfam
Q9YCI2
FunTreePfam
His456 Tyr77 Lys263 Asp132 Phe131 Asp220 Leu387
P31013
FunTreePfam
E6SFG5
FunTreePfam
Phe447 Tyr71 Lys257 Thr124 Phe123 Asp214 Arg381
P31013
FunTreePfam
Q0C406
FunTreePfam
His446 Tyr71 Lys256 Asp124 Phe123 Asp213 Ile380
P31013
FunTreePfam
P31011
FunTreePfam
Phe448 Tyr71 Lys257 Thr124 Phe123 Asp214 Arg381
P31013
FunTreePfam
Q8FBV2
FunTreePfam
His463 Tyr74 Lys270 Asp137 Phe136 Asp227 Ile396
P31013
FunTreePfam
A7ZTR3
FunTreePfam
His463 Tyr74 Lys270 Asp137 Phe136 Asp227 Ile396
P31013
FunTreePfam
Q8D5Q4
FunTreePfam
His463 Tyr74 Lys270 Asp137 Phe136 Asp227 Ile396
P31013
FunTreePfam
Q59342
FunTreePfam
His453 Tyr71 Lys261 Asp128 Phe127 Asp218 Ile386
P31013
FunTreePfam
O07674
FunTreePfam
His463 Tyr74 Lys270 Asp137 Phe136 Asp227 Ile396
P31013
FunTreePfam
O08501
FunTreePfam
Phe449 Tyr72 Lys258 Thr125 Phe124 Asp215 Arg382
P31013
FunTreePfam
A5EYI0
FunTreePfam
His463 Tyr74 Lys270 Asp137 Phe136 Asp227 Ile396
P31013
FunTreePfam
Q4QML4
FunTreePfam
His463 Tyr74 Lys270 Asp137 Phe136 Asp227 Ile396
P31013
FunTreePfam
P31012
FunTreePfam
Phe448 Tyr71 Lys257 Thr124 Phe123 Asp214 Arg381
P31013
FunTreePfam
B7LK50
FunTreePfam
His463 Tyr74 Lys270 Asp137 Phe136 Asp227 Ile396
P31013
FunTreePfam
B0R7Q6
FunTreePfam
His439 Tyr67 Lys253 Asp120 Phe119 Asp210 Leu378
P31013
FunTreePfam
Q9ZNA8
FunTreePfam
His456 Tyr70 Lys264 Asp131 Phe130 Asp221 Ile389
P31013
FunTreePfam
O30971
FunTreePfam
His446 Tyr71 Lys256 Asp124 Phe123 Asp213 Ile380
P31013
FunTreePfam
A8A6H0
FunTreePfam
His463 Tyr74 Lys270 Asp137 Phe136 Asp227 Ile396
P31013
FunTreePfam
Q0I3R5
FunTreePfam
His463 Tyr74 Lys270 Asp137 Phe136 Asp227 Ile396
P31013
FunTreePfam
Q0SYP7
FunTreePfam
His463 Tyr74 Lys270 Asp137 Phe136 Asp227 Ile396
P31013
FunTreePfam
B2TUR7
FunTreePfam
His463 Tyr74 Lys270 Asp137 Phe136 Asp227 Ile396
P31013
FunTreePfam
Q8XB34
FunTreePfam
His463 Tyr74 Lys270 Asp137 Phe136 Asp227 Ile396
P31013
FunTreePfam
A8G097
FunTreePfam
His457 Tyr71 Lys265 Asp132 Phe131 Asp222 Ile390
P31013
FunTreePfam
A4SNA7
FunTreePfam
His453 Tyr71 Lys261 Asp128 Phe127 Asp218 Ile386
P31013
FunTreePfam
B1LL35
FunTreePfam
His463 Tyr74 Lys270 Asp137 Phe136 Asp227 Ile396
P31013
FunTreePfam
A1JJH3
FunTreePfam
His457 Tyr71 Lys265 Asp132 Phe131 Asp222 Ile390
P31013
FunTreePfam
B5YXB2
FunTreePfam
His463 Tyr74 Lys270 Asp137 Phe136 Asp227 Ile396
P31013
FunTreePfam
B7M560
FunTreePfam
His463 Tyr74 Lys270 Asp137 Phe136 Asp227 Ile396
P31013
FunTreePfam
P0A854
FunTreePfam
His463 Tyr74 Lys270 Asp137 Phe136 Asp227 Ile396
P31013
FunTreePfam
B6I3U1
FunTreePfam
His463 Tyr74 Lys270 Asp137 Phe136 Asp227 Ile396
P31013
FunTreePfam
A1VC86
FunTreePfam
His453 Tyr71 Lys261 Asp128 Phe127 Asp218 Ile386
P31013
FunTreePfam
B7NR10
FunTreePfam
His463 Tyr74 Lys270 Asp137 Phe136 Asp227 Ile396
P31013
FunTreePfam
B7UMH5
FunTreePfam
His463 Tyr74 Lys270 Asp137 Phe136 Asp227 Ile396
P31013
FunTreePfam
B7N212
FunTreePfam
His463 Tyr74 Lys270 Asp137 Phe136 Asp227 Ile396
P31013
FunTreePfam
B1IX30
FunTreePfam
His463 Tyr74 Lys270 Asp137 Phe136 Asp227 Ile396
P31013
FunTreePfam
B1X9T7
FunTreePfam
His463 Tyr74 Lys270 Asp137 Phe136 Asp227 Ile396
P31013
FunTreePfam
B7MGC9
FunTreePfam
His463 Tyr74 Lys270 Asp137 Phe136 Asp227 Ile396
P31013
FunTreePfam
B7L853
FunTreePfam
His463 Tyr74 Lys270 Asp137 Phe136 Asp227 Ile396
P31013
FunTreePfam
B7NF25
FunTreePfam
His463 Tyr74 Lys270 Asp137 Phe136 Asp227 Ile396
P31013
FunTreePfam
Q0TB00
FunTreePfam
His463 Tyr74 Lys270 Asp137 Phe136 Asp227 Ile396
P31013
FunTreePfam
C4ZYY6
FunTreePfam
His463 Tyr74 Lys270 Asp137 Phe136 Asp227 Ile396
P31013
FunTreePfam
C3LUI5
FunTreePfam
His463 Tyr74 Lys270 Asp137 Phe136 Asp227 Ile396