M-CSA Mechanism and Catalytic Site Atlas

Exodeoxyribonuclease (lambda-induced) (M-CSA:549)

Proteins that are close homologues to the M-CSA reference protein and have the same catalytic residues (highlighted in green, below) probably share the same mechanism. Please also check if the homologue shares the same FunTree Structural Cluster and the same Pfam family, as another measure of similarity.

Legend:
Reference Residue Conserved Residue Non Conserved Residue Outside Alignment Reference Residue not in this sequence

Homologous SwissProt sequences of P06229

Reference Sequence	Homologue	Asp131 Asp153 Asp155 Asp201 Asp204 Asp26 Asp68 Glu128 Arg86 Lys83
P06229	P06229	Asp131 Asp153 Asp155 Asp201 Asp204 Asp26 Asp68 Glu128 Arg86 Lys83
P06229	P57506	Asp117 Asp139 Asp141 Asp186 Asp189 Asp13 Asp64 Glu114 Arg82 Lys79
P06229	P54161	Asp117 Asp138 Asp140 Asp189 Asp192 Asp10 Asp64 Glu114 Arg82 Lys79
P06229	O34996	Asp114 Asp136 Asp138 Asp187 Asp190 Asp11 Asp61 Glu111 Arg79 Lys76
P06229	P52026	Asp112 Asp134 Asp136 Asp185 Asp188 Asp9 Asp59 Glu109 Arg77 Lys74
P06229	Q1RH76	Asp114 Asp136 Asp138 Asp183 Asp186 Asp11 Asp61 Glu111 Arg79 Lys76
P06229	Q04957	Asp112 Asp134 Asp136 Asp185 Asp188 Asp9 Asp59 Glu109 Arg77 Lys74
P06229	Q8K9D0	Asp117 Asp139 Asp141 Asp186 Asp189 Asp13 Asp64 Glu114 Arg82 Lys79