M-CSA Mechanism and Catalytic Site Atlas

Bacterial leucyl aminopeptidase (M-CSA:167)

Proteins that are close homologues to the M-CSA reference protein and have the same catalytic residues (highlighted in green, below) probably share the same mechanism. Please also check if the homologue shares the same FunTree Structural Cluster and the same Pfam family, as another measure of similarity.

Legend:
Reference Residue Conserved Residue Non Conserved Residue Outside Alignment Reference Residue not in this sequence

Homologous SwissProt sequences of Q01693

Reference Sequence	Homologue	His362 Glu257 Asp223 Asp285 His203 Glu258
Q01693	Q01693	His362 Glu257 Asp223 Asp285 His203 Glu258
Q01693	E3S5D4	not aligned Glu215 Asp183 Asp243 His163 Glu216
Q01693	C0NVM2	not aligned Glu242 Asp204 Asp270 His185 Glu243
Q01693	B2W572	not aligned Glu163 Asp131 Asp191 His111 Glu164
Q01693	E4V655	not aligned Glu233 Asp195 Asp261 His176 Glu234
Q01693	Q2H1T8	not aligned Glu251 Asp213 Asp279 His194 Glu252
Q01693	D4AM42	not aligned Glu226 Asp191 Asp254 His171 Glu227
Q01693	C5FNB5	not aligned Glu223 Asp185 Asp251 His167 Glu224
Q01693	A4R640	not aligned Glu245 Asp207 Asp273 His188 Glu246
Q01693	Q5AXE5	not aligned Glu247 Asp209 Asp275 His190 Glu248
Q01693	B2B3P6	not aligned Glu245 Asp207 Asp273 His188 Glu246
Q01693	P23314	not aligned not aligned Ala341 Asp378 not aligned not aligned
Q01693	A1D9K5	not aligned Glu245 Asp207 Asp273 His188 Glu246
Q01693	P24153	Trp462 not aligned not aligned Asp371 not aligned not aligned
Q01693	C4JHZ6	not aligned Glu231 Asp196 Asp259 His176 Glu232
Q01693	D4B4V2	not aligned Glu229 Asp191 Asp257 His172 Glu230
Q01693	E5R501	not aligned Glu231 Asp199 Asp259 His179 Glu232
Q01693	Q0UNS4	not aligned Glu225 Asp181 Asp253 His161 Glu226
Q01693	E5A6Z0	not aligned Glu169 Asp137 Asp197 His117 Glu170
Q01693	Q4W9P4	not aligned Glu245 Asp207 Asp273 His188 Glu246
Q01693	C4JLL1	not aligned Glu252 Asp214 Asp280 His195 Glu253
Q01693	C5GRP9	not aligned Glu242 Asp204 Asp270 His185 Glu243
Q01693	A1C948	not aligned Glu245 Asp207 Asp273 His188 Glu246
Q01693	F0X8C8	not aligned Glu247 Asp209 Asp275 His190 Glu248
Q01693	C5FFM0	not aligned Glu233 Asp195 Asp261 His176 Glu234
Q01693	A2R2G1	not aligned Glu248 Asp210 Asp276 His191 Glu249
Q01693	B6H3H1	not aligned Glu242 Asp204 Asp270 His185 Glu243
Q01693	Q2PIT3	not aligned Glu244 Asp206 Asp272 His187 Glu245
Q01693	E3RJ99	not aligned Glu219 Asp187 Asp247 His167 Glu220
Q01693	E9DUF4	not aligned Glu240 Asp202 Asp268 His184 Glu241
Q01693	C7Z6W1	not aligned Glu239 Asp201 Asp267 His182 Glu240
Q01693	C5JX80	not aligned Glu242 Asp204 Asp270 His185 Glu243
Q01693	C5G0A8	not aligned Glu232 Asp194 Asp260 His175 Glu233
Q01693	Q7RYC8	not aligned Glu249 Asp211 Asp277 His192 Glu250
Q01693	C5FLR8	not aligned Glu232 Asp194 Asp260 His175 Glu233
Q01693	A4R017	not aligned Glu234 Asp202 Asp262 His182 Glu235
Q01693	Q2U1F3	not aligned Glu233 Asp195 Asp261 His176 Glu234
Q01693	B2W3C7	not aligned Glu219 Asp187 Asp247 His167 Glu220
Q01693	E3S6P9	not aligned Glu245 Asp207 Asp273 His188 Glu246
Q01693	D4AZ23	not aligned Glu239 Asp201 Asp267 His182 Glu240
Q01693	Q04033	not aligned Glu234 Asp196 Asp262 His177 Glu235
Q01693	E3QQU9	not aligned Glu244 Asp206 Asp272 His187 Glu245
Q01693	A6REE0	not aligned Glu242 Asp204 Asp270 His185 Glu243
Q01693	F0URV0	not aligned Glu242 Asp204 Asp270 His185 Glu243
Q01693	C1HC91	not aligned Glu246 Asp208 Asp274 His189 Glu247
Q01693	C6HH71	not aligned Glu242 Asp204 Asp270 His185 Glu243
Q01693	B2WMR5	not aligned Glu245 Asp207 Asp273 His188 Glu246
Q01693	C1GMY8	not aligned Glu246 Asp208 Asp274 His189 Glu247
Q01693	E4URG0	not aligned Glu229 Asp194 Asp257 His174 Glu230
Q01693	Q0U6L1	not aligned Glu245 Asp207 Asp273 His188 Glu246
Q01693	E9DBV9	not aligned Glu245 Asp207 Asp273 His188 Glu246
Q01693	D4AWL0	not aligned Glu223 Asp185 Asp251 His167 Glu224
Q01693	D4B528	not aligned Glu233 Asp195 Asp261 His176 Glu234
Q01693	A7ETG2	not aligned Glu244 Asp206 Asp272 His187 Glu245
Q01693	E4ZHQ5	not aligned Glu244 Asp206 Asp272 His187 Glu245
Q01693	E9F277	not aligned Glu240 Asp202 Asp268 His184 Glu241
Q01693	C5FP82	not aligned Glu237 Asp202 Asp265 His182 Glu238
Q01693	B6V870	not aligned Glu233 Asp195 Asp261 His176 Glu234
Q01693	D4DF09	not aligned Glu229 Asp191 Asp257 His172 Glu230
Q01693	P43147	Trp465 not aligned not aligned Asp374 not aligned not aligned
Q01693	B8NYX1	not aligned Glu244 Asp206 Asp272 His187 Glu245
Q01693	Q60106	Val695 not aligned Gly408 Asp518 not aligned not aligned
Q01693	P16588	not aligned not aligned Asn302 Asp339 not aligned not aligned
Q01693	Q8J2N2	not aligned Glu233 Asp195 Asp261 His176 Glu234
Q01693	B0YED6	not aligned Glu245 Asp207 Asp273 His188 Glu246
Q01693	C5P552	not aligned Glu245 Asp207 Asp273 His188 Glu246
Q01693	A4V8W0	not aligned Glu244 Asp206 Asp272 His187 Glu245
Q01693	D4D8N9	not aligned Glu226 Asp191 Asp254 His171 Glu227
Q01693	Q5QHG5	not aligned Glu233 Asp195 Asp261 His176 Glu234
Q01693	A7UI11	not aligned Glu233 Asp195 Asp261 His176 Glu234
Q01693	D4DHE3	not aligned Glu233 Asp195 Asp261 His176 Glu234
Q01693	D4DDS4	not aligned Glu239 Asp201 Asp267 His182 Glu240
Q01693	P0CH60	not aligned Glu223 Asp185 Asp251 His167 Glu224
Q01693	C0SJ49	not aligned Glu245 Asp207 Asp273 His189 Glu246
Q01693	Q00971	Trp462 not aligned not aligned Asp371 not aligned not aligned
Q01693	Q48259	Trp109 not aligned not aligned Asp19 not aligned not aligned
Q01693	Q5VJG6	not aligned Glu245 Asp207 Asp273 His188 Glu246