|
Figure 9.
Figure 9. Comparison of the NMR structure and crystal
structure. (a) The ensemble of the 20 lowest energy NMR
structures is shown in color, superimposed with the crystal
structure (shown in gray). (b) and (c) Base-pairing interactions
between the tetraloop and receptor. Hydrogen bonds are indicated
with broken lines. Residues from the tetraloop are shown in
orange and residues from the receptor are shown in cyan. The
crystal structure is in white. G8 is in a Watson-Crick pair with
C35 and forms a base quadruplet with A23 and G20 from the
tetraloop. A6 is in a reverse-Hoogsteen pair with U36, and forms
a triplet with A21 from the tetraloop.
|
