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Figure 8.
Figure 8. Stereo view representation of a modelled enzyme
IIA-HPr complex. With knowledge of the phosphorylation site, the
family of NMR structures of P-HPr (PDB code 1PFH coloured in
red) was docked into the crystallographic model of enzyme IIA.
The P-HPr ensemble of structures was rotated around the apical
axis (red line) to minimize clashes and short contacts between
the two proteins. Residues possibly involved in electrostatic
interaction are Glu64[IIA] and Arg17[HPr]. Sidechains of
His78[IIA], His82[IIA] and P-His15[HPr] are displayed and
coloured by atom type.
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