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Figure 8.
Figure 8. Conformational states along the reaction pathway (see
text). (a) G[iα1]–GTPγS–Mg^2+. (b) Structure of the
pentacoordinate intermediate modeled on the structure of the
G[iα1]–GDP–AlF[4]^−–Mg^2+ complex. (c)
G[iα1]–GDP–Pi complex modeled on the structure of
G203A–GDP–Pi. (d) G[iα1]–GDP. Color scheme is the same as
that used in Figure 3. Figure 8. Conformational states along
the reaction pathway (see text). (a) G[iα1]–GTPγS–Mg^2+.
(b) Structure of the pentacoordinate intermediate modeled on the
structure of the G[iα1]–GDP–AlF[4]^−–Mg^2+ complex. (c)
G[iα1]–GDP–Pi complex modeled on the structure of
G203A–GDP–Pi. (d) G[iα1]–GDP. Color scheme is the same as
that used in [3]Figure 3. (Figure was generated using the
program SETOR [[4]55].)
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