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Figure 8.
Fig. 8. C- and B-helix features in the bound and apo states.
(a) Three different αC-helix arrangements: cAMP-bound wild-type
(red), partially unwound (R348A in gray) and disordered (R307W
in green). The circle indicates the position of Phe341, a
residue referred to in the text (the R307W structure lacks this
residue). (b) Three examples of the αB-helix arrangement
emphasizing how it occupies two orientations: bound (wild-type
in red) and apo (R348A in gray and R307W in green). The circle
indicates the position of Leu330 (see the text).
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