Figure 8 - full size

 

Figure 8.
Figure 8. (a) Superimposition of pullulanase/G4 on pancreatic a-amylase/acarbose complex. (stereo view). The protein model and bound sugar moieties are coloured light grey and blue in pullulanase/G4 and dark grey and orange in a-amylase/acarbose, respectively. (b) A cartoon showing the glucose units of oligosaccharides and pullulan and their position at numbered subsites. G, glucose unit of G4 (blue), estimated position of pullulan (black) and estimated position of substrate in a-amylase (red). The arrow in pullan indicates the a-1,6 linkage. The triangle indicates the catalytic site.

The above figure is reprinted by permission from Elsevier: J Mol Biol (2006, 359, 690-707) copyright 2006.