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Figure 8.
Figure 8. Interactions between the catalytic domain, the
linker region and the lectin domain. Ball-and-stick
representations indicate residues responsible for the
interactions, which are shown in red, blue and magenta for the
catalytic domain, the linker region and the lectin domain,
respectively. (a) pp-GalNAc-T10. Residues Asp289, Trp290,
Lys295, Ile297, Pro298, Tyr404 and Arg408 are shown in red,
Phe449TyrProProValGluProProAlaAlaAlaTrp460 in blue, and Thr504,
Phe505, Trp507, Arg508, Ser540, Phe589, His591, Thr592, Asn593
and Val596 in magenta. (b) pp-GalNAc-T1. Residues Tyr256,
Phe259, Trp261, Tyr268, Arg273, Met374, Phe377, Phe380, Ile383
and Glu416 are shown in red,
Asp421SerGlnIleProArgHisTyrPheSerLeu431 in blue, and Gly464,
Val467, Ser469, Tyr470, Thr471, Ala472, Arg477, Asp479, His499,
Asn552 and Val553 in magenta.
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